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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 31-JAN-2014

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae TIGR4
  • locus tag: SP_1122 [new locus tag: SP_RS05555 ]
  • pan locus tag?: PNEUPAN002269000
  • symbol: glgC
  • pan gene symbol?: glgC
  • synonym:
  • product: glucose-1-phosphate adenylyltransferase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SP_1122 [new locus tag: SP_RS05555 ]
  • symbol: glgC
  • product: glucose-1-phosphate adenylyltransferase
  • replicon: chromosome
  • strand: +
  • coordinates: 1055637..1056779
  • length: 1143
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    ATGAAAAATGAAATGTTAGCTTTGATTCTTGCTGGTGGGCAAGGAACTCGTCTCGGTAAA
    CTCACTCAAAGCATCGCAAAACCAGCTGTGCAATTTGGTGGGCGCTACCGTATCATTGAC
    TTTGCCCTATCAAACTGTGCCAACTCAGGGATTCACAATGTTGGGGTCGTTACACAGTAT
    CAACCACTTGCTCTCAACAACCATATTGGGAATGGTTCAAGCTGGGGACTAGACGGTATT
    AATTCAGGTGTCTCTATTCTTCAACCTTATTCTGCAAGTGAAGGAAATCGTTGGTTTGAG
    GGGACTAGTCACGCTATTTACCAAAATATCGACTATATCGACAGTGTCAATCCTGAGTAT
    GTCTTGATTTTGTCTGGGGATCACATCTACAAAATGGACTATGATGATATGCTCCAGTCT
    CATAAGGATAATAATGCCAGCTTGACAGTAGCAGTTTTAGACGTCCCTCTTAAAGAAGCA
    AGCCGTTTTGGTATCATGAACACAGATGCTAACAATCGTATTGTTGAATTTGAAGAAAAA
    CCAGCTCAACCTAAATCTACAAAAGCTTCTATGGGAATCTACATTTTTGATTGGCAACGC
    CTTCGTAATATGTTAGTCGCTGCTGAAAAGAGCAAGGTTGGCATGTCAGACTTTGGTAAA
    AATGTCATTCCAAATTACCTTGAGTCAGGTGAAAGTGTTTATGCTTACGAATTTAGTGGT
    TATTGGAAAGATGTTGGTACTATTGAGTCACTTTGGGAAGCGAACATGGAGTATATTTCT
    CCAGAAAATGCCTTGGATAGTCGTAACCGTCAATGGAAGATTTACTCAAGAAACTTGATT
    TCACCACCAAACTTCCTCGGGGCAAATGCTCATGTGGAAGACTCATTAGTTGTAGACGGA
    TGTTTCGTTGATGGAACTGTTAAACATTCTATCCTTTCAACAGGCGCGCAAGTTCGCGAA
    GGAGCGGAAGTCCTTGATTCAGTTATCATGAGTGGAGCTATCATTGGTCAAGGAGCTAAG
    ATTAAACGTGCCATTATTGGTGAAGGTGCGATTATTTCTGACGGTGTCGAAATTGATGGA
    ACAGATGAAGTACAAGTTGTAGGATATAATGAAGTAGTGGGGGTAGCAACAGATGAAGAT
    TGA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1143

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SP_1122 [new locus tag: SP_RS05555 ]
  • symbol: GlgC
  • description: glucose-1-phosphate adenylyltransferase
  • length: 380
  • theoretical pI: 4.5345
  • theoretical MW: 41490.3
  • GRAVY: -0.187895

⊟Function[edit | edit source]

  • reaction:
    EC 2.7.7.27?  ExPASy
    Glucose-1-phosphate adenylyltransferase ATP + alpha-D-glucose 1-phosphate = diphosphate + ADP-glucose
  • TIGRFAM:
    Metabolism Energy metabolism Biosynthesis and degradation of polysaccharides glucose-1-phosphate adenylyltransferase (TIGR02091; EC 2.7.7.27; HMM-score: 487)
    and 10 more
    Metabolism Energy metabolism Biosynthesis and degradation of polysaccharides glucose-1-phosphate adenylyltransferase, GlgD subunit (TIGR02092; EC 2.7.7.27; HMM-score: 229.6)
    glucose-1-phosphate thymidylyltransferase (TIGR01208; EC 2.7.7.24; HMM-score: 114.1)
    UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase (TIGR03992; EC 2.3.1.157,2.7.7.23; HMM-score: 103.9)
    Cell structure Cell envelope Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides glucose-1-phosphate thymidylyltransferase (TIGR01207; EC 2.7.7.24; HMM-score: 79.5)
    Cell structure Cell envelope Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase (TIGR01173; EC 2.3.1.157,2.7.7.23; HMM-score: 48.9)
    Cell structure Cell envelope Biosynthesis and degradation of murein sacculus and peptidoglycan UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase (TIGR01173; EC 2.3.1.157,2.7.7.23; HMM-score: 48.9)
    Metabolism Central intermediary metabolism Amino sugars UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase (TIGR01173; EC 2.3.1.157,2.7.7.23; HMM-score: 48.9)
    Cell structure Cell envelope Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides glucose-1-phosphate cytidylyltransferase (TIGR02623; EC 2.7.7.33; HMM-score: 42.6)
    Cell structure Cell envelope Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides UTP--glucose-1-phosphate uridylyltransferase (TIGR01099; EC 2.7.7.9; HMM-score: 39.8)
    Hypothetical proteins Conserved TIGR00454 family protein (TIGR00454; HMM-score: 28.8)
  • TheSEED  :
    • Glucose-1-phosphate adenylyltransferase (EC 2.7.7.27)
    Carbohydrates Polysaccharides Glycogen metabolism  Glucose-1-phosphate adenylyltransferase (EC 2.7.7.27)
  • PFAM:
    GT-A (CL0110) NTP_transferase; Nucleotidyl transferase (PF00483; HMM-score: 227.6)
    and 3 more
    NTP_transf_3; MobA-like NTP transferase domain (PF12804; HMM-score: 37.5)
    HEXAPEP (CL0536) Hexapep; Bacterial transferase hexapeptide (six repeats) (PF00132; HMM-score: 17.4)
    DUF4954; Domain of unknown function (DUF4954) (PF16314; HMM-score: 12.6)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.118997
    • TAT(Tat/SPI): 0.016832
    • LIPO(Sec/SPII): 0.035659
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MKNEMLALILAGGQGTRLGKLTQSIAKPAVQFGGRYRIIDFALSNCANSGIHNVGVVTQYQPLALNNHIGNGSSWGLDGINSGVSILQPYSASEGNRWFEGTSHAIYQNIDYIDSVNPEYVLILSGDHIYKMDYDDMLQSHKDNNASLTVAVLDVPLKEASRFGIMNTDANNRIVEFEEKPAQPKSTKASMGIYIFDWQRLRNMLVAAEKSKVGMSDFGKNVIPNYLESGESVYAYEFSGYWKDVGTIESLWEANMEYISPENALDSRNRQWKIYSRNLISPPNFLGANAHVEDSLVVDGCFVDGTVKHSILSTGAQVREGAEVLDSVIMSGAIIGQGAKIKRAIIGEGAIISDGVEIDGTDEVQVVGYNEVVGVATDED

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator: CcpA regulon
    CcpA(TF)important in Global catabolite repression; RegPrecise 

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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