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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 31-JAN-2014

Summary[edit | edit source]

  • organism: Streptococcus pneumoniae TIGR4
  • locus tag: SP_1492 [new locus tag: SP_RS07345 ]
  • pan locus tag?: PNEUPAN002771000
  • symbol: SP_1492
  • pan gene symbol?: mucB
  • synonym:
  • product: cell wall surface anchor family protein

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: SP_1492 [new locus tag: SP_RS07345 ]
  • symbol: SP_1492
  • product: cell wall surface anchor family protein
  • replicon: chromosome
  • strand: -
  • coordinates: 1402547..1403155
  • length: 609
  • essential: unknown

Accession numbers[edit | edit source]

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    GTGGTTCCCAAAACAGCAACCTCTACTGAGACGAAGACTATAACGCGTATCATTCATTAC
    GTTGATAAAGTTACGAACCAAAATGTAAAAGAAGATGTTGTTCAACCTGTAACCTTAAGC
    CGTACAAAAACTGAGAACAAGGTCACGGGAGTTGTAACCTACGGTGAATGGACAACAGGA
    AACTGGGACGAGGTTATATCTGGTAAGATTGACAAGTACAAAGATCCAGATATTCCAACA
    GTTGAATCACAAGAAGTTACGTCAGACTCTAGTGATAAAGAAATAACGGTAAGGTATGAC
    CGTTTATCAACACCAGAAAAACCAATCCCACAACCAAATCCAGAGCATCCAAGTGTTCCG
    ACACCAAACCCAGAACTACCAAATCAAGAGACTCCAACACCAGATAAACCAACTCCAGAA
    CCAGGTACTCCAAAAACTGAAACTCCAGTGAATCCAGACCCAGAAGTTCCGACTTATGAG
    ACAGGTAAGAGAGAGGAATTGCCAAACACAGGTACAGAAGCTAATGCTACCTTGGCTAGT
    GCTGGTATCATGACCTTGTTAGCTGGTCTAGGATTAGGATTTTTCAAGAAAAAAGAAGAT
    GAAAAATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    609

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: SP_1492 [new locus tag: SP_RS07345 ]
  • symbol: SP_1492
  • description: cell wall surface anchor family protein
  • length: 202
  • theoretical pI: 4.53361
  • theoretical MW: 22208.5
  • GRAVY: -0.906931

Function[edit | edit source]

  • TIGRFAM:
    Cell structure Cell envelope Other LPXTG cell wall anchor domain (TIGR01167; HMM-score: 32.9)
    and 1 more
    pullulanase, extracellular (TIGR02102; HMM-score: 13.7)
  • TheSEED  :
    • Cell wall surface anchor family protein
    Cell Wall and Capsule Gram-Positive cell wall components Sortase  Cell wall surface anchor family protein
  • PFAM:
    Ubiquitin (CL0072) Muc_B2; Muc B2-like domain (PF17966; HMM-score: 44)
    no clan defined Gram_pos_anchor; LPXTG cell wall anchor motif (PF00746; HMM-score: 42.3)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: Cellwall
    • Cytoplasmic Score: 0.01
    • Cytoplasmic Membrane Score: 0.01
    • Cellwall Score: 9.97
    • Extracellular Score: 0.01
    • Internal Helix: 1
  • DeepLocPro: Cell wall & surface
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 0.0013
    • Cell wall & surface Score: 0.9983
    • Extracellular Score: 0.0004
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.025627
    • TAT(Tat/SPI): 0.001025
    • LIPO(Sec/SPII): 0.001611
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit | edit source]

Protein sequence[edit | edit source]

  • MVPKTATSTETKTITRIIHYVDKVTNQNVKEDVVQPVTLSRTKTENKVTGVVTYGEWTTGNWDEVISGKIDKYKDPDIPTVESQEVTSDSSDKEITVRYDRLSTPEKPIPQPNPEHPSVPTPNPELPNQETPTPDKPTPEPGTPKTETPVNPDPEVPTYETGKREELPNTGTEANATLASAGIMTLLAGLGLGFFKKKEDEK

Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

Expression & Regulation[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Transcription[edit | edit source]

  • transcription start site:

Expression data[edit | edit source]

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

Literature[edit | edit source]

References[edit | edit source]

  1. Indu Warrier, Nikhil Ram-Mohan, Zeyu Zhu, Ariana Hazery, Haley Echlin, Jason Rosch, Michelle M Meyer, Tim van Opijnen
    The Transcriptional landscape of Streptococcus pneumoniae TIGR4 reveals a complex operon architecture and abundant riboregulation critical for growth and virulence.
    PLoS Pathog: 2018, 14(12);e1007461
    [PubMed:30517198] [WorldCat.org] [DOI] (I e)

Relevant publications[edit | edit source]