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PangenomeTIGR4
serotype 4
D39serotype 2
D39Vserotype 2
Hungary19A-6serotype 19A
EF3030serotype 19F
670-6Bserotype 6B
6A-10serotype 6A
70585serotype 5
A026serotype 19F
A66serotype 3
AP200serotype 11A
ASP0581serotype 12F
ATCC 49619serotype 19F
ATCC 700669serotype 23F
BM6001serotype 19F
BVJ1JLserotype 1
CGSP14serotype 14
G54serotype 19F
HU-OHserotype 3
Hu15serotype 19A
Hu17serotype 19A
INV104serotype 1
INV200serotype 14
JJAserotype 14
MDRSPN001serotype 19F
NCTC7465serotype 1
NCTC7466serotype 2
NU83127serotype 4
OXC141serotype 3
P1031serotype 1
R6serotype 2
SP49serotype 19A
SPN032672serotype 1
SPN034156serotype 3
SPN034183serotype 3
SPN994038serotype 3
SPN994039serotype 3
SPNA45serotype 3
ST556serotype 19F
TCH8431/19Aserotype 19A
Taiwan19F-14serotype 19F
Xen35serotype 4
gamPNI0373serotype 1
NCBI: 31-JAN-2014
⊟Summary[edit | edit source]
- organism: Streptococcus pneumoniae TIGR4
- locus tag: SP_1624 [new locus tag: SP_RS08010 ]
- pan locus tag?: PNEUPAN003032000
- symbol: SP_1624
- pan gene symbol?: plsC
- synonym:
- product: acyltransferase family protein
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: SP_1624 [new locus tag: SP_RS08010 ]
- symbol: SP_1624
- product: acyltransferase family protein
- replicon: chromosome
- strand: +
- coordinates: 1525797..1526546
- length: 750
- essential: yes [1] DEG
⊟Accession numbers[edit | edit source]
- Location: AE005672 (1525797..1526546) NCBI
- BioCyc:
- MicrobesOnline: 117063 MicrobesOnline
- PneumoBrowse for strain D39V: SPV_1437 PneumoBrowse
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
- 1
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721ATGTTTTATACTTATTTGCGTGGATTAGTTGTATTGCTCTTATGGTCCATCAATGGCAAT
GCTCACTATCATAATACTGATAAAATTCCTAATCAAGATGAAAATTATATTTTAGTTGCG
CCTCACCGTACCTGGTGGGATCCTGTTTATATGGCCTTTGCGACCAAGCCAAAACAGTTC
ATCTTTATGGCAAAAAAAGAACTCTTTACCAACCGTATCTTTGGTTGGTGGATTCGTATG
TGTGGCGCCTTTCCCATCGACCGTGAAAATCCCAGCGCCTCAGCCATCAAATATCCTATC
AACGTTCTCAAAAAAAGTGACCGCTCTCTCATCATGTTTCCAAGTGGTAGCCGCCACTCA
AACGATGTCAAGGGGGGCGCAGCACTGATTGCCAAAATGGCCAAGGTCCGTATCATGCCG
GTTACCTACACCGGTCCCATGACTTTGAAGGGCTTGATTAGCCGTGAACGTGTCGATATG
AACTTTGGAAATCCAATCGATATCTCAGATATCAAGAAAATGAATGATGAAGGCATTGAA
ACAGTCGCCAATCGTATTCAAACAGAATTCCAACGTCTGGACGAAGAAACGAAACAATGG
CACAATGATAAAAAACCAAATCCACTCTGGTGGTTTATCCGCATCCCTGCCCTCATCCTT
GCTATTATCCTCGCTATCCTAACCATCATCTTTAGCTTTATCGCAAGCTTCATCTGGAAC
CCAGATAAGAAAAGAGAAGAACTTGCATAG60
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⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: SP_1624 [new locus tag: SP_RS08010 ]
- symbol: SP_1624
- description: acyltransferase family protein
- length: 249
- theoretical pI: 10.1324
- theoretical MW: 28933.6
- GRAVY: -0.164257
⊟Function[edit | edit source]
- TIGRFAM: Fatty acid and phospholipid metabolism Biosynthesis 1-acylglycerol-3-phosphate O-acyltransferases (TIGR00530; EC 2.3.1.51; HMM-score: 84.9)
- TheSEED :
- Acyl-ACP:1-acyl-sn-glycerol-3-phosphate acyltransferase (EC 2.3.1.n4)
Fatty Acids, Lipids, and Isoprenoids Phospholipids Glycerolipid and Glycerophospholipid Metabolism in Bacteria 1-acyl-sn-glycerol-3-phosphate acyltransferase (EC 2.3.1.51)and 1 more - PFAM: Acyltransferase (CL0228) Acyltransferase; Acyltransferase (PF01553; HMM-score: 67.9)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
- PSORTb: Cytoplasmic Membrane
- Cytoplasmic Score: 0.32
- Cytoplasmic Membrane Score: 9.55
- Cellwall Score: 0.12
- Extracellular Score: 0.01
- Internal Helix: 1
- DeepLocPro: Cytoplasmic Membrane
- Cytoplasmic Score: 0.0001
- Cytoplasmic Membrane Score: 0.9998
- Cell wall & surface Score: 0
- Extracellular Score: 0.0002
- SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.249549
- TAT(Tat/SPI): 0.00169
- LIPO(Sec/SPII): 0.095797
- predicted transmembrane helices (TMHMM): 1
⊟Accession numbers[edit | edit source]
⊟Protein sequence[edit | edit source]
- MFYTYLRGLVVLLLWSINGNAHYHNTDKIPNQDENYILVAPHRTWWDPVYMAFATKPKQFIFMAKKELFTNRIFGWWIRMCGAFPIDRENPSASAIKYPINVLKKSDRSLIMFPSGSRHSNDVKGGAALIAKMAKVRIMPVTYTGPMTLKGLISRERVDMNFGNPIDISDIKKMNDEGIETVANRIQTEFQRLDEETKQWHNDKKPNPLWWFIRIPALILAIILAILTIIFSFIASFIWNPDKKREELA
⊟Experimental data[edit | edit source]
- protein localization:
- interaction partners:
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
- MicrobesOnline: no polycistronic organisation predicted
⊟Regulation[edit | edit source]
- regulator:
⊟Transcription[edit | edit source]
- transcription start site: 1525773 [2]
⊟Expression data[edit | edit source]
- PneumoExpress for strain D39V: SPV_1437 PneumoExpress
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
You can add further information about the gene and protein here. [edit]
⊟Literature[edit | edit source]
⊟References[edit | edit source]
- ↑ Jane A Thanassi, Sandra L Hartman-Neumann, Thomas J Dougherty, Brian A Dougherty, Michael J Pucci
Identification of 113 conserved essential genes using a high-throughput gene disruption system in Streptococcus pneumoniae.
Nucleic Acids Res: 2002, 30(14);3152-62
[PubMed:12136097] [WorldCat.org] [DOI] (I p) - ↑ Indu Warrier, Nikhil Ram-Mohan, Zeyu Zhu, Ariana Hazery, Haley Echlin, Jason Rosch, Michelle M Meyer, Tim van Opijnen
The Transcriptional landscape of Streptococcus pneumoniae TIGR4 reveals a complex operon architecture and abundant riboregulation critical for growth and virulence.
PLoS Pathog: 2018, 14(12);e1007461
[PubMed:30517198] [WorldCat.org] [DOI] (I e)