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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 31-JAN-2014

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae TIGR4
  • locus tag: SP_1771 [new locus tag: SP_RS08775 ]
  • pan locus tag?: PNEUPAN003222000
  • symbol: SP_1771
  • pan gene symbol?: gspA_2
  • synonym:
  • product: glycosyl transferase, family 2/glycosyl transferase family 8

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SP_1771 [new locus tag: SP_RS08775 ]
  • symbol: SP_1771
  • product: glycosyl transferase, family 2/glycosyl transferase family 8
  • replicon: chromosome
  • strand: -
  • coordinates: 1676082..1678172
  • length: 2091
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: AE005672 (1676082..1678172) NCBI
  • BioCyc:
  • MicrobesOnline: 117204 MicrobesOnline
  • PneumoBrowse for strain D39V:

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    1861
    1921
    1981
    2041
    TTGCTAGTGGATGATAAAATAACAGTCATTGTACCAGTATACAATGTGGAAAACTATCTG
    AGGAAGTGCCTAGATAGTATTATTACTCAAACATATAAAAATATTGAGATTGTTGTCGTT
    AATGATGGTTCTACGGATGCTTCAGGTGAAATTTGTAAAGAATTTTCAGAAATGGATCAC
    CGAATTCTCTATATAGAACAAGAAAATGCTGGTCTTTCTGCCGCACGAAACACCGGTCTG
    AATAATATGTCCGGAAATTATGTGACCTTTGTGGACTCGGATGATTGGATTGAGCAAGAT
    TATGTAGAAACTCTATATAAAAAAATAGTAGAGTATCAGGCTGATATTGCAGTTGGTAAT
    TATTATTCTTTCAACGAAAGTGAAGGAATGTTCTACTTTCATATATTGGGAGACTCCTAT
    TATGAGAAAGTATATGATAATGTTTCTATCTTTGAGAACTTGTATGAAACTCAAGAAATG
    AAGAGTTTTGCTTTGATATCTGCTTGGGGTAAACTCTATAAGGCAAGATTGTTTGAGCAG
    TTGCGCTTTGACATAGGTAAATTAGGAGAAGATGGTTACCTCAATCAAAAGGTATATTTA
    TTATCAGAAAAGGTAATTTATTTAAATAAAAGTCTTTATGCTTATCGGATTAGAAAAGGT
    AGTTTATCAAGAGTTTGGACAGAAAAGTGGATGCACGCTTTAGTTGATGCTATGTCTGAA
    CGTATTACGCTACTAGCTAATATGGGTTATCCTCTAGAGAAACACTTGGCAGTTTATCGT
    CAGATGTTGGAAGTCAGTCTCGCCAACGGTCAAGCTAGTGGTTTATCTGACACAGCAACG
    TATAAAGAGTTTGAAATGAAACAAAGGCTTTTAAATCAGCTATCGAGACAAGAGGAAAGT
    GAAAAGAAAGCCATTGTCCTCGCAGCAAACTATGGCTATGTAGACCAAGTTTTAACGACA
    ATCAAGTCTATTTGTTATCATAATCGTTCGATTCGTTTTTATCTGATTCATAGCGATTTT
    CCAAATGAATGGATTAAGCAATTAAATAAGCGCTTAGAGAAGTTTGACTCAGAAATTATT
    AATTGTCGGGTAACTTCTGAGCAAATTTCATGTTATAAATCGGATATTAGTTACACAGTC
    TTTTTACGCTATTTCATAGCTGATTTCGTGCAAGAAGACAAGGCCCTCTACTTGGACTGT
    GATCTAGTTGTAACGAAAAATCTGGATGACTTGTTTGCTACAGACTTACAAGATTATCCT
    TTGGCTGCTGTTAGAGATTTTGGGGGCAGAGCTTATTTTGGTCAAGAAATCTTTAATGCC
    GGTGTTCTCTTGGTAAACAATGCTTTTTGGAAAAAAGAGAATATGACCCAAAAATTAATT
    GATGTAACCAATGAATGGCATGATAAGGTGGATCAGGCAGATCAGAGCATCTTGAATATG
    CTTTTTGAACATAAATGGTTGGAATTGGACTTTGATTATAATCATATTGTCATTCATAAA
    CAGTTTGCTGATTATCAATTGCCTGAGGGTCAGGATTATCCTGCTATTATTCACTATCTT
    TCTCATCGGAAACCGTGGAAAGATTTGGCGGCCCAAACCTATCGTGAAGTTTGGTGGTAC
    TATCATGGGCTTGAATGGACAGAATTGGGACAAAACCATCATTTACATCCATTACAAAGA
    TCTCACATCTATCCAATAAAGGAACCTTTCACTTGTCTAATCTATACTGCCTCAGACCAT
    ATTGAACAAATTGAGACATTGGTTCAATCCTTGCCTGATATTCAGTTTAAGATAGCAGCT
    AGAGTAATAGTTAGTGATCGATTGGCTCAGATGACAATTTATCCAAACGTGACTATATTT
    AACGGAATTCACTATTTGGTAGATGTCGATAATGAATTGGTAGAAACCAGTCAAGTACTT
    TTAGATATTAATCATGGCGAAAAGACAGAAGAAATTCTCGATCAATTTGCTAATCTTGGC
    AAGCCTATCTTATCCTTTGAAAATACTAAAACCTATGAAGTAGGTCAGGAGGCATATGCT
    GTTGACCAAGTTCAAGCAATGATTGAAAAATTGAGAGAAATAAGCAAATGA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1380
    1440
    1500
    1560
    1620
    1680
    1740
    1800
    1860
    1920
    1980
    2040
    2091

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SP_1771 [new locus tag: SP_RS08775 ]
  • symbol: SP_1771
  • description: glycosyl transferase, family 2/glycosyl transferase family 8
  • length: 696
  • theoretical pI: 4.80239
  • theoretical MW: 81335.6
  • GRAVY: -0.311494

⊟Function[edit | edit source]

  • TIGRFAM:
    poly-beta-1,6 N-acetyl-D-glucosamine synthase (TIGR03937; EC 2.4.1.-; HMM-score: 65.2)
    Genetic information processing Protein fate Protein modification and repair accessory Sec system glycosyltransferase GtfB (TIGR02919; EC 2.4.1.-; HMM-score: 63.3)
    putative glycosyltransferase, exosortase G-associated (TIGR03111; HMM-score: 61.6)
    mycofactocin system glycosyltransferase (TIGR03965; HMM-score: 59.1)
    and 9 more
    chitooligosaccharide synthase NodC (TIGR04242; EC 2.4.1.-; HMM-score: 50.1)
    Unknown function Enzymes of unknown specificity transferase 2, rSAM/selenodomain-associated (TIGR04283; EC 2.-.-.-; HMM-score: 41.3)
    colanic acid biosynthesis glycosyltransferase WcaA (TIGR04017; EC 2.4.-.-; HMM-score: 36.1)
    glycosyltransferase, TIGR04182 family (TIGR04182; HMM-score: 33.7)
    glycosyltransferase domain (TIGR04440; EC 2.-.-.-; HMM-score: 30.8)
    hopene-associated glycosyltransferase HpnB (TIGR03469; HMM-score: 27.4)
    colanic acid biosynthesis glycosyltransferase WcaE (TIGR04009; EC 2.4.-.-; HMM-score: 21.1)
    Cell structure Cell envelope Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides rhamnosyltransferase (TIGR01556; EC 2.4.1.-; HMM-score: 19)
    hopanoid biosynthesis associated glycosyl transferase protein HpnI (TIGR03472; HMM-score: 10.9)
  • TheSEED  :
    • Beta-1,3-glucosyltransferase
  • PFAM:
    GT-A (CL0110) Glyco_transf_8; Glycosyl transferase family 8 (PF01501; HMM-score: 138)
    Glycos_transf_2; Glycosyl transferase family 2 (PF00535; HMM-score: 129.6)
    and 4 more
    Glyco_tranf_2_2; Glycosyltransferase like family 2 (PF10111; HMM-score: 52.7)
    Glyco_tranf_2_3; Glycosyltransferase like family 2 (PF13641; HMM-score: 48.2)
    Glyco_tranf_2_4; Glycosyl transferase family 2 (PF13704; HMM-score: 16.9)
    no clan defined DUF6176; Family of unknown function (DUF6176) (PF19673; HMM-score: 12.1)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 1.05
    • Cytoplasmic Membrane Score: 8.78
    • Cellwall Score: 0.08
    • Extracellular Score: 0.09
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.93
    • Cytoplasmic Membrane Score: 0.0446
    • Cell wall & surface Score: 0.0016
    • Extracellular Score: 0.0238
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.00777
    • TAT(Tat/SPI): 0.000098
    • LIPO(Sec/SPII): 0.000763
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MLVDDKITVIVPVYNVENYLRKCLDSIITQTYKNIEIVVVNDGSTDASGEICKEFSEMDHRILYIEQENAGLSAARNTGLNNMSGNYVTFVDSDDWIEQDYVETLYKKIVEYQADIAVGNYYSFNESEGMFYFHILGDSYYEKVYDNVSIFENLYETQEMKSFALISAWGKLYKARLFEQLRFDIGKLGEDGYLNQKVYLLSEKVIYLNKSLYAYRIRKGSLSRVWTEKWMHALVDAMSERITLLANMGYPLEKHLAVYRQMLEVSLANGQASGLSDTATYKEFEMKQRLLNQLSRQEESEKKAIVLAANYGYVDQVLTTIKSICYHNRSIRFYLIHSDFPNEWIKQLNKRLEKFDSEIINCRVTSEQISCYKSDISYTVFLRYFIADFVQEDKALYLDCDLVVTKNLDDLFATDLQDYPLAAVRDFGGRAYFGQEIFNAGVLLVNNAFWKKENMTQKLIDVTNEWHDKVDQADQSILNMLFEHKWLELDFDYNHIVIHKQFADYQLPEGQDYPAIIHYLSHRKPWKDLAAQTYREVWWYYHGLEWTELGQNHHLHPLQRSHIYPIKEPFTCLIYTASDHIEQIETLVQSLPDIQFKIAARVIVSDRLAQMTIYPNVTIFNGIHYLVDVDNELVETSQVLLDINHGEKTEEILDQFANLGKPILSFENTKTYEVGQEAYAVDQVQAMIEKLREISK

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Expression data[edit | edit source]

  • PneumoExpress for strain D39V:

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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