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PangenomeTIGR4
serotype 4
D39serotype 2
D39Vserotype 2
Hungary19A-6serotype 19A
EF3030serotype 19F
670-6Bserotype 6B
6A-10serotype 6A
70585serotype 5
A026serotype 19F
A66serotype 3
AP200serotype 11A
ASP0581serotype 12F
ATCC 49619serotype 19F
ATCC 700669serotype 23F
BVJ1JLserotype 1
CGSP14serotype 14
G54serotype 19F
HU-OHserotype 3
Hu15serotype 19A
Hu17serotype 19A
INV104serotype 1
INV200serotype 14
JJAserotype 14
MDRSPN001serotype 19F
NCTC7466serotype 2
NU83127serotype 4
OXC141serotype 3
P1031serotype 1
R6serotype 2
SP49serotype 19A
SPN032672serotype 1
SPN034156serotype 3
SPN034183serotype 3
SPN994038serotype 3
SPN994039serotype 3
SPNA45serotype 3
ST556serotype 19F
TCH8431/19Aserotype 19A
Taiwan19F-14serotype 19F
Xen35serotype 4
gamPNI0373serotype 1
NCBI: 31-JAN-2014
⊟Summary[edit | edit source]
- organism: Streptococcus pneumoniae TIGR4
- locus tag: SP_1909 [new locus tag: SP_RS09600 ]
- pan locus tag?: PNEUPAN003502000
- symbol: SP_1909
- pan gene symbol?: ydfG
- synonym:
- product: oxidoreductase, short chain dehydrogenase/reductase family
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: SP_1909 [new locus tag: SP_RS09600 ]
- symbol: SP_1909
- product: oxidoreductase, short chain dehydrogenase/reductase family
- replicon: chromosome
- strand: -
- coordinates: 1822913..1823674
- length: 762
- essential: unknown
⊟Accession numbers[edit | edit source]
- Location: AE005672 (1822913..1823674) NCBI
- BioCyc: see SP_RS09600
- MicrobesOnline: 117337 MicrobesOnline
- PneumoBrowse for strain D39V: SPV_1712 PneumoBrowse
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
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721ATGGCAAAAAATGTTGTGATTACAGGAGCGACATCAGGAATCGGTGAAGCGATTGCGCGT
GCTTATCTGGAGCAGGGTGAGGATGTCGTTCTAACAGGACGACGGATAGACAGACTAGAA
GCTCTTAAGGCGGAGTTTGCAGAAACTTTTCCAAATCAAACAGTTTGGACTTTTCTCCTA
GATGTCACGGATATGACAATGGTAAAGACTGTCTGCTCTGATATTTTAGAAACGATAGGT
CAGATTGACATCCTGGTCAATAACGCAGGACTGGCTCTTGGCTTAGCTCCCTATCAAGAC
TATGAAGAGTTGGATATGCTGACCATGTTGGATACCAATGTCAAAGGTTTGATGGCAGTC
ACTCGCTGTTTCTTGCCAGCAATGGTAAAAGCCAATCAAGGTCATATTATCAATATGGGG
TCAACCGCAGGAATTTATGCCTATGCTGGTGCAGCTGTTTACTCAGCCACCAAGGCGGCA
GTTAAGACCTTTTCAGATGGACTGCGAATTGATACCATCGCAACGGATATCAAGGTGACG
ACCATTCAGCCTGGAATTGTCGAAACAGATTTTTCTACAGTGCGTTTTCATGGTGATAAA
GAACGAGCTGCGTCCGTTTACCAAGGAATAGAAGCTTTGCAAGCTCAGGATATTGCAGAT
ACAGTAGTCTATGTGACTAGTCAACCTCGTCGTGTTCAGATTACAGATATGACCATTATG
GCCAATCAACAGGCGACAGGTTTCATGGTTCATAAAAAATAA60
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⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: SP_1909 [new locus tag: SP_RS09600 ]
- symbol: SP_1909
- description: oxidoreductase, short chain dehydrogenase/reductase family
- length: 253
- theoretical pI: 4.6748
- theoretical MW: 27455.4
- GRAVY: 0.130435
⊟Function[edit | edit source]
- TIGRFAM: Fatty acid and phospholipid metabolism Biosynthesis 3-oxoacyl-[acyl-carrier-protein] reductase (TIGR01830; EC 1.1.1.100; HMM-score: 124.7)3-hydroxybutyrate dehydrogenase (TIGR01963; HMM-score: 123.9)2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase (TIGR04316; EC 1.3.1.28; HMM-score: 113.1)acetoacetyl-CoA reductase (TIGR01829; EC 1.1.1.36; HMM-score: 103.5)and 15 moreUnknown function Enzymes of unknown specificity SDR family mycofactocin-dependent oxidoreductase (TIGR03971; EC 1.1.99.-; HMM-score: 96.4)Energy metabolism Biosynthesis and degradation of polysaccharides 2-deoxy-D-gluconate 3-dehydrogenase (TIGR01832; EC 1.1.1.125; HMM-score: 92.2)Energy metabolism Fermentation acetoin reductases (TIGR02415; EC 1.1.1.-; HMM-score: 87.6)rhamnulose-1-phosphate aldolase/alcohol dehydrogenase (TIGR02632; EC 1.1.1.1,4.1.2.19; HMM-score: 85.7)Unknown function Enzymes of unknown specificity SDR family mycofactocin-dependent oxidoreductase (TIGR04504; EC 1.1.99.-; HMM-score: 84.4)2-hydroxycyclohexanecarboxyl-CoA dehydrogenase (TIGR03206; EC 1.1.1.-; HMM-score: 84)cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase (TIGR03325; EC 1.3.1.56; HMM-score: 66.6)Fatty acid and phospholipid metabolism Biosynthesis putative 3-oxoacyl-(acyl-carrier-protein) reductase (TIGR01831; HMM-score: 65.4)sepiapterin reductase (TIGR01500; EC 1.1.1.153; HMM-score: 58.1)pteridine reductase (TIGR02685; EC 1.5.1.33; HMM-score: 40.2)Biosynthesis of cofactors, prosthetic groups, and carriers Chlorophyll and bacteriochlorphyll light-dependent protochlorophyllide reductase (TIGR01289; EC 1.3.1.33; HMM-score: 34.3)Central intermediary metabolism Other long-chain fatty acyl-ACP reductase (aldehyde-forming) (TIGR04058; EC 1.1.1.-; HMM-score: 20.6)UDP-N-acetylglucosamine 4,6-dehydratase (inverting) (TIGR03589; EC 4.2.1.115; HMM-score: 19.1)Hypothetical proteins Conserved TIGR01777 family protein (TIGR01777; HMM-score: 14.7)hopanoid-associated sugar epimerase (TIGR03466; HMM-score: 14)
- TheSEED :
- Oxidoreductase, short-chain dehydrogenase/reductase family (EC 1.1.1.-)
- PFAM: NADP_Rossmann (CL0063) adh_short; short chain dehydrogenase (PF00106; HMM-score: 179.8)and 5 moreadh_short_C2; Enoyl-(Acyl carrier protein) reductase (PF13561; HMM-score: 130.2)KR; KR domain (PF08659; HMM-score: 45.7)Polysacc_synt_2; Polysaccharide biosynthesis protein (PF02719; HMM-score: 19.3)Epimerase; NAD dependent epimerase/dehydratase family (PF01370; HMM-score: 17.5)NAD_binding_10; NAD(P)H-binding (PF13460; HMM-score: 17.4)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
- PSORTb: Cytoplasmic
- Cytoplasmic Score: 9.97
- Cytoplasmic Membrane Score: 0
- Cellwall Score: 0.01
- Extracellular Score: 0.02
- Internal Helices: 0
- SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.008936
- TAT(Tat/SPI): 0.000434
- LIPO(Sec/SPII): 0.000956
- predicted transmembrane helices (TMHMM): 0
⊟Accession numbers[edit | edit source]
⊟Protein sequence[edit | edit source]
- MAKNVVITGATSGIGEAIARAYLEQGEDVVLTGRRIDRLEALKAEFAETFPNQTVWTFLLDVTDMTMVKTVCSDILETIGQIDILVNNAGLALGLAPYQDYEELDMLTMLDTNVKGLMAVTRCFLPAMVKANQGHIINMGSTAGIYAYAGAAVYSATKAAVKTFSDGLRIDTIATDIKVTTIQPGIVETDFSTVRFHGDKERAASVYQGIEALQAQDIADTVVYVTSQPRRVQITDMTIMANQQATGFMVHKK
⊟Experimental data[edit | edit source]
- protein localization:
- interaction partners:
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
- MicrobesOnline: SP_1909 < SP_1910 < SP_1911 < SP_1912
⊟Regulation[edit | edit source]
- regulator:
⊟Expression data[edit | edit source]
- PneumoExpress for strain D39V: SPV_1712 PneumoExpress
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
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