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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 31-JAN-2014

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae TIGR4
  • locus tag: SP_2028 [new locus tag: SP_RS10255 ]
  • pan locus tag?: PNEUPAN003659000
  • symbol: SP_2028
  • pan gene symbol?: yfkJ
  • synonym:
  • product: phosphotyrosine protein phosphatase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SP_2028 [new locus tag: SP_RS10255 ]
  • symbol: SP_2028
  • product: phosphotyrosine protein phosphatase
  • replicon: chromosome
  • strand: -
  • coordinates: 1934138..1934566
  • length: 429
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    ATGAAAAAATTAGTCTTTGTCTGTCTGGGAAATATTTGCCGTAGCCCTATGGCCGAGTTT
    GTTATGAAATCAATGACAGATAACTACGAAATCCAAAGTCGAGCAACTTCCTCTTGGGAA
    CATGGCAATCCGATTCATAAGGGGACTCAGGGAATTTTTCAAGAGTATGAGATTCCTTAT
    GACAAGAACAAGACATCGCTTCAGATTAGTAAGGAAGATTTTGAAGCCTTTGATTATATT
    ATCGGAATGGACGCTTCAAATATTTCTGACTTACGTCAGATGTGTCCAGTAGACTGTCAA
    GATAAGATTTACTCATTTTCATCTGAAAGTGTTCCAGACCCTTGGTATACAGGAGATTTT
    GAAGAAACCTATCGACGTGTTCAAGAGGGCTGTCAAGCTTGGTTAGAACGTTTAGAAAAG
    GAGAGTTAA
    60
    120
    180
    240
    300
    360
    420
    429

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SP_2028 [new locus tag: SP_RS10255 ]
  • symbol: SP_2028
  • description: phosphotyrosine protein phosphatase
  • length: 142
  • theoretical pI: 4.41697
  • theoretical MW: 16539.5
  • GRAVY: -0.648592

⊟Function[edit | edit source]

  • TIGRFAM:
    Cellular processes Cellular processes Detoxification arsenate reductase (thioredoxin) (TIGR02691; EC 1.20.4.-,3.1.3.48; HMM-score: 27.1)
    and 1 more
    Cellular processes Cellular processes Detoxification arsenate reductase, glutathione/glutaredoxin type (TIGR02689; EC 1.20.4.1; HMM-score: 18)
  • TheSEED  :
    • Low molecular weight protein tyrosine phosphatase (EC 3.1.3.48)
    LMPTP YfkJ cluster  Low molecular weight protein tyrosine phosphatase (EC 3.1.3.48)
    and 1 more
    LMPTP YwlE cluster  Low molecular weight protein tyrosine phosphatase (EC 3.1.3.48)
  • PFAM:
    Phosphatase (CL0031) LMWPc; Low molecular weight phosphotyrosine protein phosphatase (PF01451; HMM-score: 100.7)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.9953
    • Cytoplasmic Membrane Score: 0.0026
    • Cell wall & surface Score: 0
    • Extracellular Score: 0.0021
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.183899
    • TAT(Tat/SPI): 0.001352
    • LIPO(Sec/SPII): 0.033482
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MKKLVFVCLGNICRSPMAEFVMKSMTDNYEIQSRATSSWEHGNPIHKGTQGIFQEYEIPYDKNKTSLQISKEDFEAFDYIIGMDASNISDLRQMCPVDCQDKIYSFSSESVPDPWYTGDFEETYRRVQEGCQAWLERLEKES

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription[edit | edit source]

  • transcription start site:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

  1. ↑ 1.0 1.1 Indu Warrier, Nikhil Ram-Mohan, Zeyu Zhu, Ariana Hazery, Haley Echlin, Jason Rosch, Michelle M Meyer, Tim van Opijnen
    The Transcriptional landscape of Streptococcus pneumoniae TIGR4 reveals a complex operon architecture and abundant riboregulation critical for growth and virulence.
    PLoS Pathog: 2018, 14(12);e1007461
    [PubMed:30517198] [WorldCat.org] [DOI] (I e)

⊟Relevant publications[edit | edit source]

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