Jump to navigation
Jump to search
PangenomeTIGR4
serotype 4
D39serotype 2
D39Vserotype 2
Hungary19A-6serotype 19A
EF3030serotype 19F
670-6Bserotype 6B
6A-10serotype 6A
70585serotype 5
A026serotype 19F
A66serotype 3
AP200serotype 11A
ASP0581serotype 12F
ATCC 49619serotype 19F
ATCC 700669serotype 23F
BM6001serotype 19F
BVJ1JLserotype 1
CGSP14serotype 14
G54serotype 19F
HU-OHserotype 3
Hu15serotype 19A
Hu17serotype 19A
INV104serotype 1
INV200serotype 14
JJAserotype 14
MDRSPN001serotype 19F
NCTC7465serotype 1
NCTC7466serotype 2
NU83127serotype 4
OXC141serotype 3
P1031serotype 1
R6serotype 2
SP49serotype 19A
SPN032672serotype 1
SPN034156serotype 3
SPN034183serotype 3
SPN994038serotype 3
SPN994039serotype 3
SPNA45serotype 3
ST556serotype 19F
TCH8431/19Aserotype 19A
Taiwan19F-14serotype 19F
Xen35serotype 4
gamPNI0373serotype 1
NCBI: 31-JAN-2014
⊟Summary[edit | edit source]
- organism: Streptococcus pneumoniae TIGR4
- locus tag: SP_2060 [new locus tag: SP_RS10415 ]
- pan locus tag?: PNEUPAN003695000
- symbol: pcp-2
- pan gene symbol?: pcp2
- synonym: pcp
- product: pyrrolidone-carboxylate peptidase
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: SP_2060 [new locus tag: SP_RS10415 ]
- symbol: pcp-2
- product: pyrrolidone-carboxylate peptidase
- replicon: chromosome
- strand: -
- coordinates: 1961765..1962409
- length: 645
- essential: unknown
⊟Accession numbers[edit | edit source]
- Location: AE005672 (1961765..1962409) NCBI
- BioCyc:
- MicrobesOnline: 117483 MicrobesOnline
- PneumoBrowse for strain D39V: SPV_1870 PneumoBrowse
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
- 1
61
121
181
241
301
361
421
481
541
601ATGAAAGTATTAGTGACAGGTTTTGAGCCCTTTGGAGGGGAAAAGGGCAATCCAGCTTTG
GAGGCCATTAAAGGTTTACCAGCTGAAATCCATGGTGCTGAGGTCCGTTGGCTAGAGGTG
CCGACAGTTTTTCACAAATCTGCTCAAGTATTGGAAGAAGAGATGAATCGTTATCAACCT
GACTTTGTCCTTTGTATTGGGCAAGCTGGTGGAAGAACTAGTTTGACACCTGAACGAGTG
ACCATTAATCAAGACGATGCATGCATTTCTGATAACGAAGATAATCAACCGATTGACCGT
CCCATTCGCCCAGATGGTGCTTCGGCCTACTTTAGTAGTTTGCCGATTAAAGCGATGGTT
CAAGCTATAAAAAAAGAGGGCTTACCGGCCTCTGTTTCCAATACGGCAGGGACTTTTGTC
TGCAGCCATTTGATGTATCAGGCTCTCTATTTGGTAGAAAAGAAATCTCCATATGTTAAG
GCAGGTTTTATGCATATTCCTTATATGATGGAACAGGTGGTGAACAGACCGACTACTCCA
GCTATGAGTTTAGTGGATATTCGGCGAGGGATAGAAGCAGCAATCGGCGCTATAATAGAA
CATGGAGATCAGGAACTCAAGTTGGTAGGCGGAGAAACTCATTGA60
120
180
240
300
360
420
480
540
600
645
⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: SP_2060 [new locus tag: SP_RS10415 ]
- symbol: Pcp-2
- description: pyrrolidone-carboxylate peptidase
- length: 214
- theoretical pI: 5.31913
- theoretical MW: 23405.7
- GRAVY: -0.170093
⊟Function[edit | edit source]
- reaction: EC 3.4.19.3? ExPASyPyroglutamyl-peptidase I Release of an N-terminal pyroglutamyl group from a polypeptide, the second amino acid generally not being Pro
- TIGRFAM: Protein fate Degradation of proteins, peptides, and glycopeptides pyroglutamyl-peptidase I (TIGR00504; EC 3.4.19.3; HMM-score: 223.2)
- TheSEED :
- Pyrrolidone-carboxylate peptidase (EC 3.4.19.3)
- PFAM: PgaPase (CL0379) Peptidase_C15; Pyroglutamyl peptidase (PF01470; HMM-score: 245.1)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
- PSORTb: Cytoplasmic
- Cytoplasmic Score: 9.97
- Cytoplasmic Membrane Score: 0
- Cellwall Score: 0.01
- Extracellular Score: 0.02
- Internal Helices: 0
- DeepLocPro: Cytoplasmic
- Cytoplasmic Score: 0.999
- Cytoplasmic Membrane Score: 0.0001
- Cell wall & surface Score: 0.0001
- Extracellular Score: 0.0009
- SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.006202
- TAT(Tat/SPI): 0.000173
- LIPO(Sec/SPII): 0.000694
- predicted transmembrane helices (TMHMM): 0
⊟Accession numbers[edit | edit source]
⊟Protein sequence[edit | edit source]
- MKVLVTGFEPFGGEKGNPALEAIKGLPAEIHGAEVRWLEVPTVFHKSAQVLEEEMNRYQPDFVLCIGQAGGRTSLTPERVTINQDDACISDNEDNQPIDRPIRPDGASAYFSSLPIKAMVQAIKKEGLPASVSNTAGTFVCSHLMYQALYLVEKKSPYVKAGFMHIPYMMEQVVNRPTTPAMSLVDIRRGIEAAIGAIIEHGDQELKLVGGETH
⊟Experimental data[edit | edit source]
- protein localization:
- interaction partners:
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
⊟Regulation[edit | edit source]
- regulator:
⊟Transcription[edit | edit source]
- transcription start site: 1962449 [1]
⊟Expression data[edit | edit source]
- PneumoExpress for strain D39V: SPV_1870 PneumoExpress
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
You can add further information about the gene and protein here. [edit]
⊟Literature[edit | edit source]
⊟References[edit | edit source]
- ↑ 1.0 1.1 Indu Warrier, Nikhil Ram-Mohan, Zeyu Zhu, Ariana Hazery, Haley Echlin, Jason Rosch, Michelle M Meyer, Tim van Opijnen
The Transcriptional landscape of Streptococcus pneumoniae TIGR4 reveals a complex operon architecture and abundant riboregulation critical for growth and virulence.
PLoS Pathog: 2018, 14(12);e1007461
[PubMed:30517198] [WorldCat.org] [DOI] (I e)