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PangenomeTIGR4
serotype 4
D39serotype 2
D39Vserotype 2
Hungary19A-6serotype 19A
EF3030serotype 19F
670-6Bserotype 6B
6A-10serotype 6A
70585serotype 5
A026serotype 19F
A66serotype 3
AP200serotype 11A
ASP0581serotype 12F
ATCC 49619serotype 19F
ATCC 700669serotype 23F
BM6001serotype 19F
BVJ1JLserotype 1
CGSP14serotype 14
G54serotype 19F
HU-OHserotype 3
Hu15serotype 19A
Hu17serotype 19A
INV104serotype 1
INV200serotype 14
JJAserotype 14
MDRSPN001serotype 19F
NCTC7465serotype 1
NCTC7466serotype 2
NU83127serotype 4
OXC141serotype 3
P1031serotype 1
R6serotype 2
SP49serotype 19A
SPN032672serotype 1
SPN034156serotype 3
SPN034183serotype 3
SPN994038serotype 3
SPN994039serotype 3
SPNA45serotype 3
ST556serotype 19F
TCH8431/19Aserotype 19A
Taiwan19F-14serotype 19F
Xen35serotype 4
gamPNI0373serotype 1
NCBI: 23-APR-2025
⊟Summary[edit | edit source]
- organism: Streptococcus pneumoniae TIGR4
- locus tag: SP_RS03705 [old locus tag: SP_0757 ]
- pan locus tag?: PNEUPAN001698000
- symbol: ftsX
- pan gene symbol?: ftsX
- synonym:
- product: permease-like cell division protein FtsX
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
⊟Accession numbers[edit | edit source]
- Location: NC_003028 (715501..716427) NCBI
- BioCyc:
- MicrobesOnline: see SP_0757
- PneumoBrowse for strain D39V: SPV_0660 PneumoBrowse
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
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901ATGATTAGTAGATTTTTTCGCCATTTATTTGAAGCCTTAAAAAGTTTGAAACGAAATGGT
TGGATGACAGTAGCTGCTGTCAGTTCAGTCATGATTACTTTGACCTTGGTGGCAATATTT
GCATCTGTTATTTTCAATACAGCGAAACTAGCTACAGATATTGAAAATAATGTCCGTGTA
GTAGTTTATATCCGAAAGGATGTGGAAGATAATAGTCAGACAATTGAAAAAGAAGGTCAA
ACTGTTACAAATAATGACTACCACAAGGTATATGATTCTTTGAAGAACATGTCTACGGTT
AAAAGTGTTACCTTTTCAAGTAAAGAAGAACAATATGAAAAATTAACCGAGATAATGGGA
GATAACTGGAAAATCTTTGAAGGAGATGCCAATCCTCTCTATGATGCCTATATTGTAGAG
GCAAACACTCCAAATGATGTAAAAACTATAGCCGAAGATGCTAAAAAAATTGAAGGTGTC
TCTGAGGTTCAAGATGGCGGTGCCAATACAGAAAGACTCTTCAAGTTAGCTTCATTTATC
CGTGTTTGGGGACTAGGGATTGCTGCTTTGTTAATTTTTATCGCAGTTTTCTTGATTTCA
AATACCATTCGTATTACCATTATTTCCCGCAGTCGCGAAATTCAAATCATGCGCTTGGTC
GGAGCTAAAAACAGTTATATCCGTGGACCGTTCTTGTTAGAAGGAGCCTTTATCGGTTTA
TTGGGAGCTATCGCACCATCTGTTTTGGTCTTTATTGTTTATCAAATTGTTTACCAATCT
GTCAACAAATCGTTGGTAGGGCAAAATCTATCCATGATTAGTCCAGATTTATTTAGTCCG
TTGATGATTGCCCTACTATTTGTGATTGGGGTTTTCATTGGTTCATTGGGATCAGGAATA
TCCATGCGCCGATTCTTGAAGATTTAG60
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⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: SP_RS03705 [old locus tag: SP_0757 ]
- symbol: FtsX
- description: permease-like cell division protein FtsX
- length: 308
- theoretical pI: 9.38754
- theoretical MW: 34299.8
- GRAVY: 0.324351
⊟Function[edit | edit source]
- TIGRFAM: Cellular processes Cell division putative protein insertion permease FtsX (TIGR00439; HMM-score: 93.6)Protein fate Protein and peptide secretion and trafficking putative protein insertion permease FtsX (TIGR00439; HMM-score: 93.6)and 4 moreProtein fate Protein and peptide secretion and trafficking lipoprotein releasing system, transmembrane protein, LolC/E family (TIGR02212; HMM-score: 33.2)Protein fate Protein and peptide secretion and trafficking lipoprotein releasing system, transmembrane protein LolE (TIGR02213; HMM-score: 28.4)acidobacterial duplicated orphan permease (TIGR03434; HMM-score: 16.6)Plasmodium falciparum uncharacterized protein TIGR01609 (TIGR01609; HMM-score: 15.3)
- TheSEED: see SP_0757
- PFAM: Dim_A_B_barrel (CL0032) FtsX_ECD; FtsX extracellular domain (PF18075; HMM-score: 69.8)and 4 moreBPD_transp_1 (CL0404) FtsX; FtsX-like permease family (PF02687; HMM-score: 49.5)no clan defined NitrOD2; Nitrososphaera output domain 2 (PF18550; HMM-score: 16.6)P-loop_NTPase (CL0023) DUF5906; Family of unknown function (DUF5906) (PF19263; HMM-score: 13.6)no clan defined ABC_trans_CmpB; Putative ABC-transporter type IV (PF06541; HMM-score: 10.8)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
- PSORTb: Cytoplasmic Membrane
- Cytoplasmic Score: 0
- Cytoplasmic Membrane Score: 10
- Cellwall Score: 0
- Extracellular Score: 0
- Internal Helices: 4
- DeepLocPro: Cytoplasmic Membrane
- Cytoplasmic Score: 0
- Cytoplasmic Membrane Score: 0.999
- Cell wall & surface Score: 0
- Extracellular Score: 0.001
- SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.042428
- TAT(Tat/SPI): 0.00355
- LIPO(Sec/SPII): 0.005687
- predicted transmembrane helices (TMHMM): 4
⊟Accession numbers[edit | edit source]
⊟Protein sequence[edit | edit source]
- MISRFFRHLFEALKSLKRNGWMTVAAVSSVMITLTLVAIFASVIFNTAKLATDIENNVRVVVYIRKDVEDNSQTIEKEGQTVTNNDYHKVYDSLKNMSTVKSVTFSSKEEQYEKLTEIMGDNWKIFEGDANPLYDAYIVEANTPNDVKTIAEDAKKIEGVSEVQDGGANTERLFKLASFIRVWGLGIAALLIFIAVFLISNTIRITIISRSREIQIMRLVGAKNSYIRGPFLLEGAFIGLLGAIAPSVLVFIVYQIVYQSVNKSLVGQNLSMISPDLFSPLMIALLFVIGVFIGSLGSGISMRRFLKI
⊟Experimental data[edit | edit source]
- protein localization:
- interaction partners:
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
- MicrobesOnline: prfB > ftsE > ftsX
⊟Regulation[edit | edit source]
- regulator:
⊟Transcription[edit | edit source]
- transcription start site:
⊟Expression data[edit | edit source]
- PneumoExpress for strain D39V: SPV_0660 PneumoExpress
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
You can add further information about the gene and protein here. [edit]
⊟Literature[edit | edit source]
⊟References[edit | edit source]
- ↑ Tim van Opijnen, Andrew Camilli
A fine scale phenotype-genotype virulence map of a bacterial pathogen.
Genome Res: 2012, 22(12);2541-51
[PubMed:22826510] [WorldCat.org] [DOI] (I p)