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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 23-APR-2025

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae TIGR4
  • locus tag: SP_RS04285 [old locus tag: SP_0870 ]
  • pan locus tag?: PNEUPAN001821000
  • symbol: sufU
  • pan gene symbol?: sufE2
  • synonym:
  • product: Fe-S cluster assembly sulfur transfer protein SufU

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SP_RS04285 [old locus tag: SP_0870 ]
  • symbol: sufU
  • product: Fe-S cluster assembly sulfur transfer protein SufU
  • replicon: chromosome
  • strand: +
  • coordinates: 816805..817245
  • length: 441
  • essential: yes [1]

⊟Accession numbers[edit | edit source]

  • Location: NC_003028 (816805..817245) NCBI
  • BioCyc:
  • MicrobesOnline: see SP_0870
  • PneumoBrowse for strain D39V: SPV_0765 PneumoBrowse

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    ATGGCACTTTCTAAACTAGATAGCCTTTATATGGCAGTGGTAGCAGACCATTCGAAAAAT
    CCACATCACCAAGGGAAGTTAGAAGATGCTGAGCAAATCAGTCTCAACAATCCGACTTGT
    GGGGATGTCATCAACCTCTCTGTCAAGTTTGATGCAGAGGACCGTTTGGAAGATATTGCT
    TTTCTAAATTCAGGATGCACGATTTCAACTGCTTCTGCTAGTATGATGACAGATGCCGTT
    TTAGGAAAAACCAAACAAGAAATTTTAGAACTGGCGACTATTTTTTCTGAAATGGTTCAA
    GGGCAAAAAGATGAGCGTCAAGACCAACTTGGAGACGCGGCATTCTTGTCAGGTGTTGCC
    AAATTCCCTCAAAGAATCAAGTGTGCAACCCTAGCTTGGAATGCCCTTAAGAAAACAATT
    GAAAATCAAGAAAAACAGTAA
    60
    120
    180
    240
    300
    360
    420
    441

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SP_RS04285 [old locus tag: SP_0870 ]
  • symbol: SufU
  • description: Fe-S cluster assembly sulfur transfer protein SufU
  • length: 146
  • theoretical pI: 4.78236
  • theoretical MW: 16015.1
  • GRAVY: -0.307534

⊟Function[edit | edit source]

  • TIGRFAM:
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Other SUF system FeS assembly protein, NifU family (TIGR01994; HMM-score: 183.9)
    and 4 more
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Other FeS cluster assembly scaffold protein NifU (TIGR03419; HMM-score: 70)
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Other FeS cluster assembly scaffold IscU (TIGR01999; HMM-score: 59.3)
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Other Fe-S cluster assembly protein NifU (TIGR02000; HMM-score: 41.7)
    Metabolism Central intermediary metabolism Nitrogen fixation Fe-S cluster assembly protein NifU (TIGR02000; HMM-score: 41.7)
  • TheSEED: see SP_0870
  • PFAM:
    SufE_NifU (CL0233) NifU_N; NifU-like N terminal domain (PF01592; HMM-score: 95.3)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: unknown (no significant prediction)
    • Cytoplasmic Score: 2.5
    • Cytoplasmic Membrane Score: 2.5
    • Cellwall Score: 2.5
    • Extracellular Score: 2.5
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.9748
    • Cytoplasmic Membrane Score: 0.0052
    • Cell wall & surface Score: 0.0002
    • Extracellular Score: 0.0199
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.016434
    • TAT(Tat/SPI): 0.000356
    • LIPO(Sec/SPII): 0.002279
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MALSKLDSLYMAVVADHSKNPHHQGKLEDAEQISLNNPTCGDVINLSVKFDAEDRLEDIAFLNSGCTISTASASMMTDAVLGKTKQEILELATIFSEMVQGQKDERQDQLGDAAFLSGVAKFPQRIKCATLAWNALKKTIENQEKQ

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription[edit | edit source]

  • transcription start site: see SP_0870

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

  1. ↑ Tim van Opijnen, Andrew Camilli
    A fine scale phenotype-genotype virulence map of a bacterial pathogen.
    Genome Res: 2012, 22(12);2541-51
    [PubMed:22826510] [WorldCat.org] [DOI] (I p)

⊟Relevant publications[edit | edit source]

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