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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 23-APR-2025

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae TIGR4
  • locus tag: SP_RS07530 [old locus tag: SP_1529 ]
  • pan locus tag?: PNEUPAN002813000
  • symbol: SP_RS07530
  • pan gene symbol?: ytgP
  • synonym:
  • product: putative polysaccharide biosynthesis protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SP_RS07530 [old locus tag: SP_1529 ]
  • symbol: SP_RS07530
  • product: putative polysaccharide biosynthesis protein
  • replicon: chromosome
  • strand: -
  • coordinates: 1439697..1441319
  • length: 1623
  • essential: yes [1] DEG

⊟Accession numbers[edit | edit source]

  • Location: NC_003028 (1439697..1441319) NCBI
  • BioCyc:
  • MicrobesOnline: see SP_1529
  • PneumoBrowse for strain D39V: SPV_1358 PneumoBrowse

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    ATGTCGCACGAAAACAATCACCAGCAGGCCCAGATGTTACGGGGGACTGCTTGGCTAACG
    GCTAGTAACTTTATCAGTCGCCTACTCGGGGCTGTTTACATTATCCCTTGGTACATCTGG
    ATGGGGGCTTATGCAGCTAAGGCAAATGGTCTCTTTACCATGGGTTACAATATCTATGCT
    TGGTTCTTGTTGGTTTCAACAGCGGGGATTCCAGTTGCGGTGGCCAAGCAAGTTGCCAAG
    TATAATACCATGCGAGAAGAAGAGCATAGCTTTGCCCTGATTCGGAGCTTCTTAGGCTTT
    ATGACAGGACTAGGCCTGGTTTTTGCTTTAGTCTTGTATGTCTTTGCTCCTTGGCTAGCA
    GACTTGTCTGGCGTGGGCAAAGACTTGATCCCAATCATGCAAAGCTTGGCTTGGGGAGTC
    TTGATTTTCCCGTCTATGAGTGTTATCCGAGGATTTTTCCAAGGGATGAATAACCTCAAA
    CCCTATGCCATGAGCCAAATTGCTGAGCAGGTCATTCGTGTTATCTGGATGCTCCTAGCA
    ACCTTTATCATTATGAAGCTCGGTTCAGGAGATTATCTAGCAGCCGTTACCCAATCAACC
    TTTGCTGCCTTTGTCGGTATGGTAGCCAGTTTTGCAGTCTTGATTTATTTCCTTGCCCAA
    GAAGGTTCACTCAAAAGAATCTTTGAAACAGGAGATAAGATTAACAGTAAGCGTCTCTTG
    GTTGATACCATTAAGGAAGCCATTCCTTTTATCCTGACAGGGTCTGCCATCCAGCTCTTC
    CAGATTTTGGATCAGCTGACCTTTATCAATAGTATGAGCTGGTTTACCAACTACAGCAAT
    GAGGACTTGGTTGTCATGTTTTCTTATTTCTCAGCCAATCCTAATAAAATCACGATGATT
    TTGATTTCTGTAGGGGTTTCGATTGGGAGTGTTGGTTTGCCACTTTTGACGGAAAACTAT
    GTCAAGGGGGACTTGAAAGCAGCTTCTCGTCTCGTTCAGGACAGTCTCACCCTACTCTTT
    ATGTTCTTGCTACCAGCAACGGTTGGAGTGGTTATGGTAGGAGAACCTCTTTATACGGTC
    TTCTATGGTAAGCCAGATAGTTTGGCTCTGGGCTTATTTGTCTTTGCAGTTTTGCAGTCT
    ATTATTTTAGGCTTGTACATGGTCTTGTCTCCAATGCTTCAGGCCATGTTCCGCAACCGC
    AAGGCCGTTCTCTATTTTATCTATGGTTCTATTGCCAAGCTAGTCTTGCAACTACCTACC
    ATCGCCCTCTTCCACAGTTATGGTCCTTTGATTTCAACAACCATTGCTCTCATCATTCCT
    AACGTCTTGATGTATCGGGATATTTGTAAAGTAACTGGTGTCAAGCGCAAGGTGATTTTG
    AAGCGAACCATTTTAATCAGTTTGCTGACCCTAGTCATGTTTCTGTTAATAGGAACCATC
    CAGTGGCTGTTAGGATTTTTCTTCCAACCAAGTGGACGTTTGTGGAGCTTCTTTTATGTA
    GCTCTTGTCGGTGCCATGGGGGGTGGACTTTATATGGTTATGAGTCTGCGTACCTATTTA
    TTAGATAAGGTAATAGGAAAAGCCCAAGCAGATCGCCTGCGAGCAAAATTTAAGCTTTCG
    TAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1380
    1440
    1500
    1560
    1620
    1623

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SP_RS07530 [old locus tag: SP_1529 ]
  • symbol: SP_RS07530
  • description: putative polysaccharide biosynthesis protein
  • length: 540
  • theoretical pI: 10.1231
  • theoretical MW: 60116.5
  • GRAVY: 0.726852

⊟Function[edit | edit source]

  • TIGRFAM:
    Cellular processes Cellular processes Sporulation and germination stage V sporulation protein B (TIGR02900; HMM-score: 117.8)
    and 1 more
    Cell structure Cell envelope Biosynthesis and degradation of murein sacculus and peptidoglycan murein biosynthesis integral membrane protein MurJ (TIGR01695; HMM-score: 43.1)
  • TheSEED: see SP_1529
  • PFAM:
    MviN_MATE (CL0222) Polysacc_synt; Polysaccharide biosynthesis protein (PF01943; HMM-score: 112.5)
    and 3 more
    Polysacc_synt_C; Polysaccharide biosynthesis C-terminal domain (PF14667; HMM-score: 77.1)
    MurJ; Lipid II flippase MurJ (PF03023; HMM-score: 45.1)
    MatE; MatE (PF01554; HMM-score: 26)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 14
  • DeepLocPro: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 1
    • Cell wall & surface Score: 0
    • Extracellular Score: 0
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.020785
    • TAT(Tat/SPI): 0.002719
    • LIPO(Sec/SPII): 0.006808
  • predicted transmembrane helices (TMHMM): 14

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MSHENNHQQAQMLRGTAWLTASNFISRLLGAVYIIPWYIWMGAYAAKANGLFTMGYNIYAWFLLVSTAGIPVAVAKQVAKYNTMREEEHSFALIRSFLGFMTGLGLVFALVLYVFAPWLADLSGVGKDLIPIMQSLAWGVLIFPSMSVIRGFFQGMNNLKPYAMSQIAEQVIRVIWMLLATFIIMKLGSGDYLAAVTQSTFAAFVGMVASFAVLIYFLAQEGSLKRIFETGDKINSKRLLVDTIKEAIPFILTGSAIQLFQILDQLTFINSMSWFTNYSNEDLVVMFSYFSANPNKITMILISVGVSIGSVGLPLLTENYVKGDLKAASRLVQDSLTLLFMFLLPATVGVVMVGEPLYTVFYGKPDSLALGLFVFAVLQSIILGLYMVLSPMLQAMFRNRKAVLYFIYGSIAKLVLQLPTIALFHSYGPLISTTIALIIPNVLMYRDICKVTGVKRKVILKRTILISLLTLVMFLLIGTIQWLLGFFFQPSGRLWSFFYVALVGAMGGGLYMVMSLRTYLLDKVIGKAQADRLRAKFKLS

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

  1. ↑ Jane A Thanassi, Sandra L Hartman-Neumann, Thomas J Dougherty, Brian A Dougherty, Michael J Pucci
    Identification of 113 conserved essential genes using a high-throughput gene disruption system in Streptococcus pneumoniae.
    Nucleic Acids Res: 2002, 30(14);3152-62
    [PubMed:12136097] [WorldCat.org] [DOI] (I p)

⊟Relevant publications[edit | edit source]

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