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PangenomeTIGR4
serotype 4
D39serotype 2
D39Vserotype 2
Hungary19A-6serotype 19A
EF3030serotype 19F
670-6Bserotype 6B
6A-10serotype 6A
70585serotype 5
A026serotype 19F
A66serotype 3
AP200serotype 11A
ASP0581serotype 12F
ATCC 49619serotype 19F
ATCC 700669serotype 23F
BM6001serotype 19F
BVJ1JLserotype 1
CGSP14serotype 14
G54serotype 19F
HU-OHserotype 3
Hu15serotype 19A
Hu17serotype 19A
INV104serotype 1
INV200serotype 14
JJAserotype 14
MDRSPN001serotype 19F
NCTC7465serotype 1
NCTC7466serotype 2
NU83127serotype 4
OXC141serotype 3
P1031serotype 1
R6serotype 2
SP49serotype 19A
SPN032672serotype 1
SPN034156serotype 3
SPN034183serotype 3
SPN994038serotype 3
SPN994039serotype 3
SPNA45serotype 3
ST556serotype 19F
TCH8431/19Aserotype 19A
Taiwan19F-14serotype 19F
Xen35serotype 4
gamPNI0373serotype 1
NCBI: 23-APR-2025
⊟Summary[edit | edit source]
- organism: Streptococcus pneumoniae TIGR4
- locus tag: SP_RS08640 [old locus tag: SP_1746 ]
- pan locus tag?: PNEUPAN003176000
- symbol: yqeK
- pan gene symbol?: yqeK
- synonym:
- product: bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: SP_RS08640 [old locus tag: SP_1746 ]
- symbol: yqeK
- product: bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK
- replicon: chromosome
- strand: -
- coordinates: 1648618..1649211
- length: 594
- essential: unknown
⊟Accession numbers[edit | edit source]
- Location: NC_003028 (1648618..1649211) NCBI
- BioCyc:
- MicrobesOnline: see SP_1746
- PneumoBrowse for strain D39V: SPV_1556 PneumoBrowse
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
- 1
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541ATGTCCTATCAAGACTATATCAACTGCTCCCGTGAGGCCTTGTTGGAAAAAATGGCAGAG
CTTCTACCTGAGAAACGTCTAACCCATTGTCTAGGTGTGGAGCGTGCCGCTATGGAATTA
GCTCAGCGCTTTGGTGTAGATGTTGAGAAAGCAAGTCTAGCAGGTCTTCTTCATGACTAT
GCTAAAAAGTTGTCAGATCAGGAATTTCTAGTCTTGATTGACCGTTACCAGCTAGACCCT
GACCTCAAAAACTGGGGCAATAATGTCTGGCATGGTATGGTCGGAATTTACAAAATTCAG
GAAGATTTGGATTTGCATGATTCTGAAATTCTGCGAGCCATTGAAATTCATACAGTCGGA
GCTGGTCAAATGACAGACCTAGATAAGGTCATCTACGTCGCAGACTATATCGAGCACAAT
CGAGCCTTTCCTGGAGTAGATGTGGCGCGTGAGATTGCAAGTCTATCGCTCAATAAGGCG
GTGGCCTACGAAACAGCTCGTACCGTGGAGTATCTAGCTCATCAGGGATTCCCCATCTAT
CCCCAAACCCTTGAAACCTATAACGCCTTTGTGCACTATTTGAAAGAGGACTAA60
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540
594
⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: SP_RS08640 [old locus tag: SP_1746 ]
- symbol: YqeK
- description: bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK
- length: 197
- theoretical pI: 4.73932
- theoretical MW: 22548.5
- GRAVY: -0.240102
⊟Function[edit | edit source]
- reaction: EC 3.6.1.41? ExPASyBis(5'-nucleosyl)-tetraphosphatase (symmetrical) P1,P4-bis(5'-adenosyl) tetraphosphate + H2O = 2 ADP
- TIGRFAM: Unknown function Enzymes of unknown specificity putative HD superfamily hydrolase (TIGR00488; HMM-score: 151.9)and 4 moreHDIG domain (TIGR00277; HMM-score: 29.8)Hypothetical proteins Conserved TIGR00295 family protein (TIGR00295; HMM-score: 22)Transcription Degradation of RNA ribonuclease Y (TIGR03319; EC 3.1.-.-; HMM-score: 14.4)CRISPR-associated endonuclease Cas3-HD (TIGR01596; EC 3.1.-.-; HMM-score: 12.6)
- TheSEED: see SP_1746
- PFAM: HD_PDEase (CL0237) HD; HD domain (PF01966; HMM-score: 49.9)and 2 moreHDOD; HDOD domain (PF08668; HMM-score: 14.6)PKinase (CL0016) HipA_C; HipA-like C-terminal domain (PF07804; HMM-score: 12)
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
- PSORTb: Cytoplasmic
- Cytoplasmic Score: 7.5
- Cytoplasmic Membrane Score: 1.15
- Cellwall Score: 0.62
- Extracellular Score: 0.73
- Internal Helices: 0
- DeepLocPro: Cytoplasmic
- Cytoplasmic Score: 0.9994
- Cytoplasmic Membrane Score: 0.0001
- Cell wall & surface Score: 0
- Extracellular Score: 0.0005
- SignalP: no predicted signal peptide
- SP(Sec/SPI): 0.002238
- TAT(Tat/SPI): 0.000434
- LIPO(Sec/SPII): 0.000366
- predicted transmembrane helices (TMHMM): 0
⊟Accession numbers[edit | edit source]
⊟Protein sequence[edit | edit source]
- MSYQDYINCSREALLEKMAELLPEKRLTHCLGVERAAMELAQRFGVDVEKASLAGLLHDYAKKLSDQEFLVLIDRYQLDPDLKNWGNNVWHGMVGIYKIQEDLDLHDSEILRAIEIHTVGAGQMTDLDKVIYVADYIEHNRAFPGVDVAREIASLSLNKAVAYETARTVEYLAHQGFPIYPQTLETYNAFVHYLKED
⊟Experimental data[edit | edit source]
- protein localization:
- interaction partners:
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
- MicrobesOnline: SP_RS08620 < SP_RS08625 < rsfS < SP_RS08635 < yqeK < SP_RS08645 < yhbYStringTie [1] : SP_RS08620 < SP_RS08625 < rsfS < SP_RS08635 < yqeK < SP_RS08645 < yhbY < yqeH < SP_RS08660 < SP_RS08665 < SP_RS08670
⊟Regulation[edit | edit source]
- regulator:
⊟Transcription[edit | edit source]
- transcription start site:
⊟Expression data[edit | edit source]
- PneumoExpress for strain D39V: SPV_1556 PneumoExpress
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
You can add further information about the gene and protein here. [edit]
⊟Literature[edit | edit source]
⊟References[edit | edit source]
- ↑ 1.0 1.1 Indu Warrier, Nikhil Ram-Mohan, Zeyu Zhu, Ariana Hazery, Haley Echlin, Jason Rosch, Michelle M Meyer, Tim van Opijnen
The Transcriptional landscape of Streptococcus pneumoniae TIGR4 reveals a complex operon architecture and abundant riboregulation critical for growth and virulence.
PLoS Pathog: 2018, 14(12);e1007461
[PubMed:30517198] [WorldCat.org] [DOI] (I e)