From PneumoWiki
Jump to navigation Jump to search
PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 23-APR-2025

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae TIGR4
  • locus tag: SP_RS09820 [old locus tag: SP_1954 ]
  • pan locus tag?: PNEUPAN003572000
  • symbol: SP_RS09820
  • pan gene symbol?: slgP2
  • synonym:
  • product: S8 family peptidase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SP_RS09820 [old locus tag: SP_1954 ]
  • symbol: SP_RS09820
  • product: S8 family peptidase
  • replicon: chromosome
  • strand: +
  • coordinates: 1857985..1859397
  • length: 1413
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: NC_003028 (1857985..1859397) NCBI
  • BioCyc:
  • MicrobesOnline: see SP_1954
  • PneumoBrowse for strain D39V: SPV_1753 PneumoBrowse

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    ATGAAGATTATGAAAAAAAAATATTGGACTTTAGCGATATTATTCTTTTGTTTGTTCAAT
    AATTCTGTTACTGCTCAAGAAATACCTAAAAATCTTGATGGCAATATAACTCACACTCAG
    ACTAGCGAAAGTTTTTCTGAATCTGATGAAAAACAGGTTGACTATTCTAATAAAAATCAA
    GAAGAAGTAGACCAAAATAAATTTCGTATTCAAATCGATAAGACAGAATTATTTGTAACA
    ACAGATAAACATTTAGAAAAAAACTGTTGTAAATTGGAACTTGAACCACAAATAAATAAC
    GATATTGTTAACTCTGAAAGTAATAATTTACTAGGCGAAGATAATTTAGATAATAAAATT
    AAGGAAAATGTTTCTCATCTAGATAATAGAGGAGGAAATATAGAGCATGACAAAGATAAC
    TTAGAATCGTCGATTGTAAGAAAATATGAATGGGATATAGATAAAGTTACTGGTGGAGGC
    GAAAGTTATAAATTATATTCTAAAAGTAATTCTAAAGTTTCAATTGCTATTTTAGATTCA
    GGAGTCGATTTACAAAATACTGGATTACTGAAAAATCTTTCAAATCACTCAAAAAACTAT
    GTCCCCAATAAAGGATATTTAGGAAAAGAGGAGGGAGAGGAAGGAATAATATCAGATATT
    CAAGATAGATTAGGTCATGGTACGGCTGTTGTAGCTCAAATTGTAGGGGATGACAATATT
    AATGGAGTAAATCCTCACGTTAATATTAACGTCTATAGAATATTTGGTAAGTCGTCAGCT
    AGTCCAGATTGGATTGTAAAAGCAATTTTTGATGCTGTAGATGATGGCAATGATATTATC
    AATCTTAGTACTGGACAATATTTAATGATTGATGGAGAATATGAGGACGGAACAAATGAT
    TTTGAAACATTTTTGAAGTATAAAAAGGCTATTGATTACGCGAATCAAAAAGGAGTAATT
    ATAGTAGCTGCATTAGGGAATGACTCCCTAAATGTATCAAATCAGTCAGATTTATTGAAA
    CTTATTAGTTCACGCAAAAAAGTAAGAAAACCAGGATTAGTAGTTGATGTTCCAAGTTAT
    TTCTCATCTACAATTTCGGTCGGAGGCATAGATCGCTTAGGTAATTTATCAGATTTTAGC
    AATAAAGGGGATTCTGATGCAATATATGCGCCTGCAGGCTCAACATTATCTCTTTCAGAA
    TTAGGACTTAATAACTTTATTAATGCAGAAAAATATAAAGAAGATTGGATTTTTTCGGCA
    ACACTAGGAGGATATACGTATCTTTATGGAAACTCATTTGCTGCTCCTAAAGTTTCTGGT
    GCGATTGCAATGATTATTGATAAATACAAATTAAAAGATCAGCCCTATAATTATATGTTT
    GTAAAAAAATTCTGGAAGAAACATTACCAGTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1380
    1413

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SP_RS09820 [old locus tag: SP_1954 ]
  • symbol: SP_RS09820
  • description: S8 family peptidase
  • length: 470
  • theoretical pI: 5.05511
  • theoretical MW: 52563.4
  • GRAVY: -0.511702

⊟Function[edit | edit source]

  • reaction:
    EC 3.4.-.-?  ExPASy
  • TIGRFAM:
    Genetic information processing Protein fate Protein and peptide secretion and trafficking type VII secretion-associated serine protease mycosin (TIGR03921; EC 3.4.21.-; HMM-score: 97.2)
    Genetic information processing Protein fate Protein modification and repair type VII secretion-associated serine protease mycosin (TIGR03921; EC 3.4.21.-; HMM-score: 97.2)
    and 1 more
    cyanobactin maturation protease, PatA/PatG family (TIGR03895; EC 3.4.21.-; HMM-score: 33.9)
  • TheSEED: see SP_1954
  • PFAM:
    no clan defined Peptidase_S8; Subtilase family (PF00082; HMM-score: 142.8)
    and 1 more
    OB (CL0021) RPA43_OB; RPA43 OB domain in RNA Pol I (PF17875; HMM-score: 14.8)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Extracellular
    • Cytoplasmic Score: 0.01
    • Cytoplasmic Membrane Score: 0.09
    • Cellwall Score: 0.18
    • Extracellular Score: 9.72
    • Internal Helices: 0
  • SignalP: Signal peptide SP(Sec/SPI) length 25 aa
    • SP(Sec/SPI): 0.989449
    • TAT(Tat/SPI): 0.000244
    • LIPO(Sec/SPII): 0.004262
    • Cleavage Site: CS pos: 25-26. VTA-QE. Pr: 0.9572
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MKIMKKKYWTLAILFFCLFNNSVTAQEIPKNLDGNITHTQTSESFSESDEKQVDYSNKNQEEVDQNKFRIQIDKTELFVTTDKHLEKNCCKLELEPQINNDIVNSESNNLLGEDNLDNKIKENVSHLDNRGGNIEHDKDNLESSIVRKYEWDIDKVTGGGESYKLYSKSNSKVSIAILDSGVDLQNTGLLKNLSNHSKNYVPNKGYLGKEEGEEGIISDIQDRLGHGTAVVAQIVGDDNINGVNPHVNINVYRIFGKSSASPDWIVKAIFDAVDDGNDIINLSTGQYLMIDGEYEDGTNDFETFLKYKKAIDYANQKGVIIVAALGNDSLNVSNQSDLLKLISSRKKVRKPGLVVDVPSYFSSTISVGGIDRLGNLSDFSNKGDSDAIYAPAGSTLSLSELGLNNFINAEKYKEDWIFSATLGGYTYLYGNSFAAPKVSGAIAMIIDKYKLKDQPYNYMFVKKFWKKHYQ

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

Retrieved from "http://pneumowiki.med.uni-greifswald.de/index.php?title=SP_RS09820&oldid=1902"