PangenomeTIGR4

serotype 4

D39

serotype 2

D39V

serotype 2

Hungary19A-6

serotype 19A

EF3030

serotype 19F

670-6B

serotype 6B

6A-10

serotype 6A

70585

serotype 5

A026

serotype 19F

A66

serotype 3

AP200

serotype 11A

ASP0581

serotype 12F

ATCC 49619

serotype 19F

ATCC 700669

serotype 23F

BM6001

serotype 19F

BVJ1JL

serotype 1

CGSP14

serotype 14

G54

serotype 19F

HU-OH

serotype 3

Hu15

serotype 19A

Hu17

serotype 19A

INV104

serotype 1

INV200

serotype 14

JJA

serotype 14

MDRSPN001

serotype 19F

NCTC7465

serotype 1

NCTC7466

serotype 2

NU83127

serotype 4

OXC141

serotype 3

P1031

serotype 1

R6

serotype 2

SP49

serotype 19A

SPN032672

serotype 1

SPN034156

serotype 3

SPN034183

serotype 3

SPN994038

serotype 3

SPN994039

serotype 3

SPNA45

serotype 3

ST556

serotype 19F

TCH8431/19A

serotype 19A

Taiwan19F-14

serotype 19F

Xen35

serotype 4

gamPNI0373

serotype 1

NCBI: 31-JAN-2014

⊟Summary

• organism: Streptococcus pneumoniae A026
• locus tag: T308_06175 [new locus tag: T308_RS06275 ]
• pan locus tag^?: PNEUPAN000081000
• symbol: T308_06175
• pan gene symbol^?: xerA
• synonym:
• product: integrase

⊟Genome View

⊟Gene

⊟General

• type: CDS
• locus tag: T308_06175 [new locus tag: T308_RS06275 ]
• symbol: T308_06175
• product: integrase
• replicon: chromosome
• strand: -
• coordinates: 1211112..1212077
• length: 966
• essential: unknown

⊟Accession numbers

• Location: CP006844 (1211112..1212077) NCBI
• BioCyc: see T308_RS06275
• MicrobesOnline:
• PneumoBrowse for strain D39V:

⊟Phenotype

Share your knowledge and add information here. [edit]

⊟DNA sequence

• 1
  61
  121
  181
  241
  301
  361
  421
  481
  541
  601
  661
  721
  781
  841
  901
  961
  
  ATGGAATCAAAAGTTACAATTATCATGCAAGAAATGTTACCTCTTTTAAATAATGAACAA
  TTACTAGCGTTGAGAGAGAGTTTAGAACATCATCTAGTAGACGGAAAAAAGCAGCAGAAG
  TATTCGAATAATAACCTGTTGCAACTATTTATTACCGCCAAGCAGGTAGAGGGCTGTAGC
  TCAAAAACAATTCGTTATTACCAGAGGACGATTGAAAACTTGTTTAATGCTATTAAAGAG
  TCTGTGACACAACTCACAACAGATGATTTAAGGAGTTATTTAGCAAATTACCAGTCTGAA
  AAGGATTGTAGTAAGGCAAATTTAGACAATATTAGGCGTATATTGTCTTCTTTTTTTGCT
  TGGCTTGAGCAAGAGGAATATATCATTAAAAATCCCATTCGACGGATAAAGAAAATTAAG
  ACTGAGCAAAATGTGAAGGAAACTTATACTGATGAACATTTGGAAATTATGCGTGATAAC
  TGTGAAAATTTGAGAGATTTGGCAATAATAGACCTACTAGCATCGACAGGTATGCGTGTA
  GGGGAGCTTGTACAGTTGAATCGTTCAGATATTGATTTTGAAAACAGAGAGTGTGTTGTC
  TTTGGTAAAGGAAAGAAGGAGAGACCAGTATATTTTGATGCTCGGACGAAAATTCATTTA
  AGAAATTATCTTAACGACAGAAAAGATAGTCACCCTGCTCTTTTTGTAACGCTAGTTGGA
  AAAGTCCAGAGACTTGGAATTGCTGGTGTAGAGATTCGCTTAAGAAAGTTAGGAGACAAA
  CTCGGCATACAAAAGGTTCACCCACATAAGTTCAGAAGAACTTTAGCGACTAAGGCAATT
  GATAAAGGTATGCCTATCGAACAAGTCCAAAAACTGCTAGGTCATAGCAAGATTGACACA
  ACCCTGGCCTATGCCATGGTCAATCAAAATAATGTCAAGCATTCACACCAAAAATTCATC
  TCTTAA
  60
  120
  180
  240
  300
  360
  420
  480
  540
  600
  660
  720
  780
  840
  900
  960
  966
  

⊟Protein

⊟General

• locus tag: T308_06175 [new locus tag: T308_RS06275 ]
• symbol: T308_06175
• description: integrase
• length: 321
• theoretical pI: 9.89426
• theoretical MW: 37309.8
• GRAVY: -0.534891

⊟Function

• TIGRFAM:
  Genetic information processing DNA metabolism DNA replication, recombination, and repair tyrosine recombinase XerC (TIGR02224; HMM-score: 171.7)
  Genetic information processing DNA metabolism DNA replication, recombination, and repair tyrosine recombinase XerD (TIGR02225; HMM-score: 145.9)
  and 2 more
  Genetic information processing DNA metabolism DNA replication, recombination, and repair integron integrase (TIGR02249; HMM-score: 77.9)
  Genetic information processing Mobile and extrachromosomal element functions Other integron integrase (TIGR02249; HMM-score: 77.9)
• TheSEED: data available for Hungary19A-6, TIGR4
• PFAM:
  DNA-mend (CL0382) Phage_integrase; Phage integrase family (PF00589; HMM-score: 117)
  and 7 more
  l-integrase_N (CL0469) Phage_int_SAM_4; Phage integrase, N-terminal SAM-like domain (PF13495; HMM-score: 61.6)
  Phage_int_SAM_1; Phage integrase, N-terminal SAM-like domain (PF02899; HMM-score: 32.6)
  no clan defined DUF6761; Family of unknown function (DUF6761) (PF20547; HMM-score: 15.4)
  EF_hand (CL0220) EF-hand_like; Phosphoinositide-specific phospholipase C, efhand-like (PF09279; HMM-score: 14.3)
  DNA_clamp (CL0060) DNA_PPF; DNA polymerase processivity factor (PF02916; HMM-score: 12.9)
  TPR (CL0020) ComR_TPR; ComR tetratricopeptide (PF18710; HMM-score: 11.5)
  no clan defined DUF5889; Family of unknown function (DUF5889) (PF19237; HMM-score: 11.4)

⊟Structure, modifications & cofactors

• domains:
• modifications:
• cofactors:
• effectors:

⊟Localization

• PSORTb: Cytoplasmic
  • Cytoplasmic Score: 9.97
  • Cytoplasmic Membrane Score: 0
  • Cellwall Score: 0.01
  • Extracellular Score: 0.02
  • Internal Helices: 0
• DeepLocPro: Cytoplasmic
  • Cytoplasmic Score: 0.9977
  • Cytoplasmic Membrane Score: 0.0013
  • Cell wall & surface Score: 0.0005
  • Extracellular Score: 0.0004
• SignalP: no predicted signal peptide
  • SP(Sec/SPI): 0.007038
  • TAT(Tat/SPI): 0.000237
  • LIPO(Sec/SPII): 0.000706
• predicted transmembrane helices (TMHMM): 0

⊟Accession numbers

• GI:
• RefSeq: AGZ47954 NCBI
• UniProt:

⊟Protein sequence

• MESKVTIIMQEMLPLLNNEQLLALRESLEHHLVDGKKQQKYSNNNLLQLFITAKQVEGCSSKTIRYYQRTIENLFNAIKESVTQLTTDDLRSYLANYQSEKDCSKANLDNIRRILSSFFAWLEQEEYIIKNPIRRIKKIKTEQNVKETYTDEHLEIMRDNCENLRDLAIIDLLASTGMRVGELVQLNRSDIDFENRECVVFGKGKKERPVYFDARTKIHLRNYLNDRKDSHPALFVTLVGKVQRLGIAGVEIRLRKLGDKLGIQKVHPHKFRRTLATKAIDKGMPIEQVQKLLGHSKIDTTLAYAMVNQNNVKHSHQKFIS

⊟Experimental data

• protein localization:
• interaction partners:

⊟Expression & Regulation

⊟Operon

⊟Regulation

• regulator:

⊟Expression data

• PneumoExpress for strain D39V:

⊟Biological Material

⊟Mutants

⊟Expression vector

⊟lacZ fusion

⊟GFP fusion

⊟two-hybrid system

⊟FLAG-tag construct

⊟Antibody

⊟Other Information

You can add further information about the gene and protein here. [edit]

⊟Literature

⊟References

⊟Relevant publications