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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 11-DEC-2024

Summary[edit | edit source]

  • organism: Streptococcus pneumoniae A026
  • locus tag: T308_RS13215
  • pan locus tag?: PNEUPAN001718000
  • symbol: T308_RS13215
  • pan gene symbol?: hsdS_3
  • synonym:
  • product: restriction endonuclease subunit S

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: T308_RS13215
  • symbol: T308_RS13215
  • product: restriction endonuclease subunit S
  • replicon: chromosome
  • strand: -
  • coordinates: <1210566..1211078
  • length: 513
  • essential: unknown

Accession numbers[edit | edit source]

  • Location: NC_022655 <1210566..1211078 NCBI
  • BioCyc:
  • MicrobesOnline:
  • PneumoBrowse for strain D39V:

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    ATGAAGAAAGTGAAATTAGGGCAAGTGGCTACTTTTATCAATGGCTATGCTTTTAAACCT
    CAAGATTGGTCATCTGAAGGGAAAGAGATTATCAGAATACAGAATCTGACTAAAACTTCA
    AAAGGGATAAATTATTATTCGGGTACGATTGATAAAAAATACATTGTTGAAGCTGGTGAT
    ATTCTTATTTCGTGGTCGGGTACATTAGGGGTTTTTCAGTGGTGTGGAAGATCCGCAGTG
    TTAAATCAGCACATTTTTAAAGTGGTTTTTGATAAGATAGATATAGATAAATCGTATTTT
    AAATATGTTGTTGAAAAAGGTTTGCAAGATGCTGTAAAACATACTCATGGTTCCACAATG
    AAACATTTAACTAAAAAATATTTTGATAATATTATGGTTTCATATACAAATTTGAGAGAG
    CAACAAAGAATTGCAAGTGAGCTGGATTTGTTAAGCAAGCTGATTTTAAGGAGACAAGAA
    CAACTTGAAGAGCTTAATCTACTTGTATACTCT
    60
    120
    180
    240
    300
    360
    420
    480
    513

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: T308_RS13215
  • symbol: T308_RS13215
  • description: restriction endonuclease subunit S
  • length: 171
  • theoretical pI: 9.84194
  • theoretical MW: 19774.7
  • GRAVY: -0.306433

Function[edit | edit source]

  • reaction:
    EC 3.1.21.-?  ExPASy
  • TIGRFAM:
  • TheSEED: data available for Hungary19A-6
  • PFAM:
    TRD (CL0477) Methylase_S; Type I restriction modification DNA specificity domain (PF01420; HMM-score: 68.4)
    and 1 more
    GT-C (CL0111) Glucan_synthase; 1,3-beta-glucan synthase component (PF02364; HMM-score: 15.4)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.8458
    • Cytoplasmic Membrane Score: 0.0208
    • Cell wall & surface Score: 0.0008
    • Extracellular Score: 0.1326
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.067868
    • TAT(Tat/SPI): 0.000517
    • LIPO(Sec/SPII): 0.012513
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_235047313 NCBI
  • UniProt:

Protein sequence[edit | edit source]

  • MKKVKLGQVATFINGYAFKPQDWSSEGKEIIRIQNLTKTSKGINYYSGTIDKKYIVEAGDILISWSGTLGVFQWCGRSAVLNQHIFKVVFDKIDIDKSYFKYVVEKGLQDAVKHTHGSTMKHLTKKYFDNIMVSYTNLREQQRIASELDLLSKLILRRQEQLEELNLLVYS

Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Expression data[edit | edit source]

  • PneumoExpress for strain D39V:

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]