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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 31-JAN-2014

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae JJA
  • locus tag: SPJ_2173 [new locus tag: SPJ_RS10775 ]
  • pan locus tag?: PNEUPAN000442000
  • symbol: arcA
  • pan gene symbol?: arcA
  • synonym:
  • product: arginine deiminase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPJ_2173 [new locus tag: SPJ_RS10775 ]
  • symbol: arcA
  • product: arginine deiminase
  • replicon: chromosome
  • strand: +
  • coordinates: 2023405..2024634
  • length: 1230
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    ATGTCTTCACATCCAATTCAGGTCTTCTCAGAAATTGGGAAACTGAAAAAAGTTATGTTG
    CACCGTCCAGGCAAGGAGTTAGAAAACTTGTTGCCGGACTATCTTGAAAGGCTTCTTTTT
    GATGATATTCCTTTCTTGGAAGATGCTCAAAAAGAACATGATGCATTTGCCCAAGCTCTT
    CGCGATGAAGGAATTGAGGTTCTCTACCTAGAACAACTCGCTGCTGAATCATTGACCTCT
    CCAGAAATCCGCGATCAATTTATCGAGGAATACTTAGACGAAGCCAACATCCGTGATCGT
    CAAACTAAGGTTGCTATTCGTGAATTGCTTCACGGCATCAAGGACAACCAAGAATTGGTT
    GAAAAAACAATGGCTGGGATTCAAAAAGTTGAATTGCCAGAAATTCCTGACGAAGCTAAA
    GATCTAACTGACTTAGTTGAATCAGATTATCCATTTGCAATTGACCCGATGCCAAACCTC
    TATTTCACTCGCGACCCATTTGCAACAATTGGAAACGCCGTATCGCTTAACCACATGTTT
    GCAGACACTCGTAACCGTGAAACACTCTACGGTAAGTATATCTTCAAATACCACCCAATC
    TATGGCGGAAAAGTGGATTTGGTCTACAACCGTGAAGAAGATACGCGTATCGAAGGTGGA
    GACGAGCTAGTTCTTTCTAAAGACGTCCTTGCAGTAGGTATCTCTCAACGTACAGACGCA
    GCTTCTATCGAAAAACTTTTGGTCAACATCTTCAAGAAAAATGTTGGCTTCAAGAAAGTT
    TTGGCCTTTGAATTTGCTAACAACCGTAAATTCATGCACTTGGATACTGTCTTCACTATG
    GTAGACTATGACAAGTTCACTATTCACCCAGAAATCGAAGGCGACCTTCACGTTTACTCA
    GTTACTTACGAAAACGAAAAACTTAAAATTGTTGAAGAGAAAGGTGACTTAGCTGAACTT
    CTTGCTCAAAACCTTGGTGTAGAAAAAGTTCATTTGATTCGTTGCGGTGGTGGCAATATC
    GTAGCAGCTGCGCGTGAACAATGGAACGACGGTTCTAACACTTTGACCATCGCACCTGGT
    GTGGTAGTTGTTTATGACCGCAATACCGTGACCAATAAGATTTTGGAAGAATACGGGCTT
    CGCTTGATTAAGATTCGCGGAAGTGAATTGGTTCGGGGCCGTGGTGGACCTCGTTGTATG
    TCTATGCCATTTGAACGTGAAGAAGTGTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1230

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPJ_2173 [new locus tag: SPJ_RS10775 ]
  • symbol: ArcA
  • description: arginine deiminase
  • length: 409
  • theoretical pI: 4.72161
  • theoretical MW: 46652.8
  • GRAVY: -0.335208

⊟Function[edit | edit source]

  • ⊞reaction:
    EC 3.5.3.6?  ExPASy
    Arginine deiminase L-arginine + H2O = L-citrulline + NH3
  • TIGRFAM:
    Metabolism Energy metabolism Amino acids and amines arginine deiminase (TIGR01078; EC 3.5.3.6; HMM-score: 598.2)
  • ⊞TheSEED  :
    • Arginine deiminase (EC 3.5.3.6)
    Amino Acids and Derivatives Arginine; urea cycle, polyamines Arginine and Ornithine Degradation  Arginine deiminase (EC 3.5.3.6)
    and 1 more
    Amino Acids and Derivatives Arginine; urea cycle, polyamines Arginine Deiminase Pathway  Arginine deiminase (EC 3.5.3.6)
  • ⊞PFAM:
    GME (CL0197) ADI; Arginine deiminase (PF02274; HMM-score: 405.2)
    and 2 more
    DDAH_eukar; N,N dimethylarginine dimethylhydrolase, eukaryotic (PF19420; HMM-score: 53.3)
    TPR (CL0020) Atx10homo_assoc; Spinocerebellar ataxia type 10 protein domain (PF09759; HMM-score: 12.8)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • ⊞PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • ⊞SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.000829
    • TAT(Tat/SPI): 0.000078
    • LIPO(Sec/SPII): 0.000134
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MSSHPIQVFSEIGKLKKVMLHRPGKELENLLPDYLERLLFDDIPFLEDAQKEHDAFAQALRDEGIEVLYLEQLAAESLTSPEIRDQFIEEYLDEANIRDRQTKVAIRELLHGIKDNQELVEKTMAGIQKVELPEIPDEAKDLTDLVESDYPFAIDPMPNLYFTRDPFATIGNAVSLNHMFADTRNRETLYGKYIFKYHPIYGGKVDLVYNREEDTRIEGGDELVLSKDVLAVGISQRTDAASIEKLLVNIFKKNVGFKKVLAFEFANNRKFMHLDTVFTMVDYDKFTIHPEIEGDLHVYSVTYENEKLKIVEEKGDLAELLAQNLGVEKVHLIRCGGGNIVAAAREQWNDGSNTLTIAPGVVVVYDRNTVTNKILEEYGLRLIKIRGSELVRGRGGPRCMSMPFEREEV

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • ⊞regulators: ArgR2* (activation (repression)) regulon, AhrC* (activation (repression)) regulon, ArgR1* (activation (repression)) regulon

⊟Expression data[edit | edit source]

⊞Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊞Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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