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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 14-DEC-2020

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae MDRSPN001
  • locus tag: MDRSPN_RS03395 [old locus tag: MDRSPN_00633 ]
  • pan locus tag?: PNEUPAN002783000
  • symbol: MDRSPN_RS03395
  • pan gene symbol?: aapA
  • synonym:
  • product: DUF4059 family protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: MDRSPN_RS03395 [old locus tag: MDRSPN_00633 ]
  • symbol: MDRSPN_RS03395
  • product: DUF4059 family protein
  • replicon: chromosome
  • strand: +
  • coordinates: 645509..645733
  • length: 225
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: NZ_AP018391 (645509..645733) NCBI
  • BioCyc:
  • MicrobesOnline:
  • PneumoBrowse for strain D39V: SPV_1288 PneumoBrowse

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    ATGCTACTGCAACTATTTTCTTTATATTTCGAGAGTTTGATCTTGACCACCATCCTTGTT
    CTGATTTTTTTAGGGATTTGGATTGGTCTGAGAGCCATGTCGGGAGTTGATAAGACAGCC
    AGGGCTCGTCAAGCCCATCTCTATGATATGATTATGATTGGAGTCTTGGTTGTCCCAGTA
    TTATCCTTTGCGGTTATGAGTTTAATTCTTGTTTTCAAGGCATAA
    60
    120
    180
    225

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: MDRSPN_RS03395 [old locus tag: MDRSPN_00633 ]
  • symbol: MDRSPN_RS03395
  • description: DUF4059 family protein
  • length: 74
  • theoretical pI: 9.9256
  • theoretical MW: 8286.22
  • GRAVY: 1.43378

⊟Function[edit | edit source]

  • TIGRFAM:
    TIGR03943 family protein (TIGR03943; HMM-score: 14.5)
  • TheSEED: data available for D39, Hungary19A-6, TIGR4
  • ⊞PFAM:
    no clan defined DUF4059; Protein of unknown function (DUF4059) (PF13268; HMM-score: 105.3)
    and 1 more
    CAF1C_H4-bd; Histone-binding protein RBBP4 or subunit C of CAF1 complex (PF12265; HMM-score: 12.8)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • ⊞PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0.32
    • Cytoplasmic Membrane Score: 9.55
    • Cellwall Score: 0.12
    • Extracellular Score: 0.01
    • Internal Helices: 2
  • ⊞SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.003066
    • TAT(Tat/SPI): 0.000426
    • LIPO(Sec/SPII): 0.003273
  • predicted transmembrane helices (TMHMM): 2

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_000926600 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MLLQLFSLYFESLILTTILVLIFLGIWIGLRAMSGVDKTARARQAHLYDMIMIGVLVVPVLSFAVMSLILVFKA

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Expression data[edit | edit source]

⊞Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊞Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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