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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 30-JAN-2014

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae CGSP14
  • locus tag: SPCG_0143 [new locus tag: SPCG_RS00780 ]
  • pan locus tag?: PNEUPAN000862000
  • symbol: mutR
  • pan gene symbol?: mutR1
  • synonym:
  • product: transcriptional regulator

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPCG_0143 [new locus tag: SPCG_RS00780 ]
  • symbol: mutR
  • product: transcriptional regulator
  • replicon: chromosome
  • strand: +
  • coordinates: 142954..143841
  • length: 888
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    ATGCAAAAGCTAGGAGGTGGTAGGATGATTGAAAAAATGGAACTGGGGGAATTTTACAAG
    GAATTGCGTTTGGCGAGAAAGCTCAAGCAGTCAGATGTGGCTTGTGCTGGACTAACAGCT
    TCTCAGCTATCCAAGTTCGAACTAGGGCAGTCTATGCTGTCTGCGGATAAGCTCATACTA
    GCCATCCAAGGGATCAATGTGACCTTTGATGAGTTTGGGCACAAGCTCAACAACTATCAA
    GAATCTCCACATATGCAGATTGGTAGAAAGATTGTGGATCGCTTTGCTCATCAAGATATA
    GCTGGCTTAGAGCAACTGTTGGAGGAAGTCGAGCAAGGACAGATGGCGGAGACCTATCGT
    CGTTTGAATGCTATTGTGATTAAAAATGCACTCCATTCCTTAGATAAAAGCTATCCGCTA
    GCAGAGGAGGATAGCGAGTTTTTGACTACCTACCTCTATGCTATTGAGTCTTGGACCTGG
    TTTGAACTCTATCTTTTTTGCAATACCATGCCCTTCTTGAGCAATCAAGATCTGATCTTT
    TTATCAACCTCTTTGCTTGAAAAATCCAAGGAATTTAAAGAGTTGGTACATAATAGACTG
    TATATGAAAAGTGGCTTTCTGAATATTATATCAGAGCTCATGGAGCGCAAGCTTTTCTCC
    TATATCCCAATCTTTGAAGCAGAGCTGGAGAGCATGTTGCGTCCGTACGATGTTTTTGAA
    AAAGTATTGTGGCAATTTTTAAAGAAAATGAGTATTTTCCTTCAAACCAAAGGAAACAAT
    CAAAAAGAGATTGAAAATTTTATCCAATCTCTGCAAGTATTAGAAAATCCACAATTAACA
    TCCCTTTTTGAACTACGCTTACAGCAATACAAAGCACTTATCGATTAG
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    888

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPCG_0143 [new locus tag: SPCG_RS00780 ]
  • symbol: MutR
  • description: transcriptional regulator
  • length: 295
  • theoretical pI: 5.27887
  • theoretical MW: 34475.7
  • GRAVY: -0.210169

⊟Function[edit | edit source]

  • ⊞TIGRFAM:
    Signal transduction Regulatory functions DNA interactions transcriptional activator, Rgg/GadR/MutR family, C-terminal domain (TIGR01716; HMM-score: 219.7)
    and 1 more
    Signal transduction Regulatory functions DNA interactions transcriptional regulator, y4mF family (TIGR03070; HMM-score: 12.5)
  • TheSEED  :
    • Positive transcriptional regulator, MutR family
  • ⊞PFAM:
    HTH (CL0123) HTH_3; Helix-turn-helix (PF01381; HMM-score: 26)
    HTH_19; Helix-turn-helix domain (PF12844; HMM-score: 23.1)
    and 4 more
    HTH_31; Helix-turn-helix domain (PF13560; HMM-score: 14)
    CDA (CL0109) LpxI_C; LpxI C-terminal domain (PF06230; HMM-score: 13.2)
    no clan defined DUF4795; Domain of unknown function (DUF4795) (PF16043; HMM-score: 11.7)
    KNTase_C (CL0291) HEPN_Apea; Apea-like HEPN (PF18739; HMM-score: 8.2)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • ⊞PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • ⊞SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.011124
    • TAT(Tat/SPI): 0.001882
    • LIPO(Sec/SPII): 0.001746
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: ACB89395 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MQKLGGGRMIEKMELGEFYKELRLARKLKQSDVACAGLTASQLSKFELGQSMLSADKLILAIQGINVTFDEFGHKLNNYQESPHMQIGRKIVDRFAHQDIAGLEQLLEEVEQGQMAETYRRLNAIVIKNALHSLDKSYPLAEEDSEFLTTYLYAIESWTWFELYLFCNTMPFLSNQDLIFLSTSLLEKSKEFKELVHNRLYMKSGFLNIISELMERKLFSYIPIFEAELESMLRPYDVFEKVLWQFLKKMSIFLQTKGNNQKEIENFIQSLQVLENPQLTSLFELRLQQYKALID

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

⊟Expression data[edit | edit source]

⊞Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊞Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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