TIGR4

serotype 4

D39

serotype 2

D39V

serotype 2

Hungary19A-6

serotype 19A

EF3030

serotype 19F

670-6B

serotype 6B

6A-10

serotype 6A

70585

serotype 5

A026

serotype 19F

A66

serotype 3

AP200

serotype 11A

ASP0581

serotype 12F

ATCC 49619

serotype 19F

ATCC 700669

serotype 23F

BVJ1JL

serotype 1

CGSP14

serotype 14

G54

serotype 19F

HU-OH

serotype 3

Hu15

serotype 19A

Hu17

serotype 19A

INV104

serotype 1

INV200

serotype 14

JJA

serotype 14

MDRSPN001

serotype 19F

NCTC7466

serotype 2

NU83127

serotype 4

OXC141

serotype 3

P1031

serotype 1

R6

serotype 2

SP49

serotype 19A

SPN032672

serotype 1

SPN034156

serotype 3

SPN034183

serotype 3

SPN994038

serotype 3

SPN994039

serotype 3

SPNA45

serotype 3

ST556

serotype 19F

TCH8431/19A

serotype 19A

Taiwan19F-14

serotype 19F

Xen35

serotype 4

gamPNI0373

serotype 1

NCBI: 31-JAN-2014

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⊟Summary

• organism: Streptococcus pneumoniae TIGR4
locus tag: SP_0206
pan locus tag^?:
symbol: SP_0206
pan gene symbol^?: —
• synonym:
• product: hypothetical protein

⊟Genome View

⊟Gene

⊟General

• type: CDS
• locus tag: SP_0206
• symbol: SP_0206
• product: hypothetical protein
• replicon: chromosome
• strand: +
• coordinates: 192159..192461
• length: 303
• essential: unknown

⊟Accession numbers

• Location: AE005672 (192159..192461) NCBI
• BioCyc:
• MicrobesOnline: 115745 MicrobesOnline
• PneumoBrowse for strain D39V:

⊟Phenotype

Share your knowledge and add information here. [edit]

⊟DNA sequence

• 1
  61
  121
  181
  241
  301
  
  ATGAAGAAAAAGGACTTAGTAGACCAACTAGTCTCAGAGATCGAGACGGGGAAAGTCAGG
  ACACTGGGAATATACGGTCATGGAGCTTCAGGTAAATCAACCTTTGCACAGGAATTGTAC
  CAAGCTTTAGATTCTACTACAGTAAATTTGCTAGAGACAGATCCTTATATCACCTCAGGA
  CGCCATCTGGTAGTACCCAAGGACGCGCCGAATCAAAAGGTGACAGCCAGTCTGCCAGTG
  GCGCATGAACTGGAGAGTTTGCAGAGAGATATCCTTGCTTGCAGGCGGGTATGGATGTCT
  TGA
  60
  120
  180
  240
  300
  303
  

⊟Protein

⊟General

• locus tag: SP_0206
• symbol: SP_0206
• description: hypothetical protein
• length: 100
• theoretical pI: 7.60781
• theoretical MW: 11066.6
• GRAVY: -0.284

⊟Function

• ⊞TIGRFAM:
  Metabolism Purines, pyrimidines, nucleosides, and nucleotides Salvage of nucleosides and nucleotides uridine kinase (TIGR00235; EC 2.7.1.48; HMM-score: 21.1)
  and 9 more
  arsenical pump-driving ATPase (TIGR04291; EC 3.6.1.-; HMM-score: 16)
  Metabolism Transport and binding proteins Unknown substrate energy-coupling factor transporter ATPase (TIGR04521; EC 3.6.3.-; HMM-score: 14.5)
  Metabolism Central intermediary metabolism Nitrogen fixation nitrogenase iron protein (TIGR01287; EC 1.18.6.1; HMM-score: 14.1)
  Metabolism Transport and binding proteins Amino acids, peptides and amines LAO/AO transport system ATPase (TIGR00750; EC 2.7.-.-; HMM-score: 13.5)
  Signal transduction Regulatory functions Protein interactions LAO/AO transport system ATPase (TIGR00750; EC 2.7.-.-; HMM-score: 13.5)
  Metabolism Transport and binding proteins Unknown substrate energy-coupling factor transporter ATPase (TIGR04520; EC 3.6.3.-; HMM-score: 13.3)
  Genetic information processing DNA metabolism DNA replication, recombination, and repair phage/plasmid primase, P4 family, C-terminal domain (TIGR01613; HMM-score: 13)
  Genetic information processing Mobile and extrachromosomal element functions Prophage functions phage/plasmid primase, P4 family, C-terminal domain (TIGR01613; HMM-score: 13)
  Metabolism Energy metabolism Photosynthesis chlorophyllide reductase iron protein subunit X (TIGR02016; HMM-score: 10.8)
• TheSEED  :
  • FIG01114116: hypothetical protein
• ⊞PFAM:
  P-loop_NTPase (CL0023) AAA_16; AAA ATPase domain (PF13191; HMM-score: 20.6)
  AAA_33; AAA domain (PF13671; HMM-score: 19.7)
  and 13 more
  NB-ARC; NB-ARC domain (PF00931; HMM-score: 15.7)
  KTI12; Chromatin associated protein KTI12 (PF08433; HMM-score: 14)
  MeaB; Methylmalonyl Co-A mutase-associated GTPase MeaB (PF03308; HMM-score: 13.8)
  ATP_bind_1; Conserved hypothetical ATP binding protein (PF03029; HMM-score: 13.7)
  Fer4_NifH; 4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family (PF00142; HMM-score: 13.2)
  PRK; Phosphoribulokinase / Uridine kinase family (PF00485; HMM-score: 13.1)
  DO-GTPase1; Double-GTPase 1 (PF19975; HMM-score: 12.3)
  HHH (CL0198) HHH_4; Helix-hairpin-helix containing domain (PF14490; HMM-score: 12.2)
  P-loop_NTPase (CL0023) RNA_helicase; RNA helicase (PF00910; HMM-score: 12.1)
  AAA_PrkA; PrkA AAA domain (PF08298; HMM-score: 12)
  AB_hydrolase (CL0028) Chlorophyllase; Chlorophyllase (PF07224; HMM-score: 11.5)
  P-loop_NTPase (CL0023) GTP_EFTU; Elongation factor Tu GTP binding domain (PF00009; HMM-score: 11.4)
  Parvo_NS1; Parvovirus non-structural protein NS1 (PF01057; HMM-score: 11.3)

⊟Structure, modifications & cofactors

• domains:
• modifications:
• cofactors:
• effectors:

⊟Localization

• ⊞PSORTb: Cytoplasmic
  • Cytoplasmic Score: 7.5
  • Cytoplasmic Membrane Score: 1.15
  • Cellwall Score: 0.62
  • Extracellular Score: 0.73
  • Internal Helices: 0
• ⊞SignalP: no predicted signal peptide
  • SP(Sec/SPI): 0.030744
  • TAT(Tat/SPI): 0.008226
  • LIPO(Sec/SPII): 0.003368
• predicted transmembrane helices (TMHMM): 0

⊟Accession numbers

• GI:
• RefSeq: AAK74386 NCBI
• UniProt: A0A0H2UN64 UniProt

⊟Protein sequence

• MKKKDLVDQLVSEIETGKVRTLGIYGHGASGKSTFAQELYQALDSTTVNLLETDPYITSGRHLVVPKDAPNQKVTASLPVAHELESLQRDILACRRVWMS

⊟Experimental data

• protein localization:
• interaction partners:

⊟Expression & Regulation

⊟Operon

• MicrobesOnline: nrdD > SP_0203 > SP_0204 > nrdG > SP_0206 > SP_0207

⊟Regulation

• regulator:

⊟Expression data

• PneumoExpress for strain D39V:

⊞Biological Material

⊟Mutants

⊟Expression vector

⊟lacZ fusion

⊟GFP fusion

⊟two-hybrid system

⊟FLAG-tag construct

⊟Antibody

⊞Other Information

You are kindly invited to share additional interesting facts.

⊟Literature

⊟References

⊟Relevant publications