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From PneumoWiki
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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 09-APR-2021

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae TIGR4
  • locus tag: SP_RS05930 [old locus tag: SP_1207 ]
  • pan locus tag?: PNEUPAN002471000
  • symbol: SP_RS05930
  • pan gene symbol?: xseA
  • synonym:
  • product: exodeoxyribonuclease VII large subunit

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SP_RS05930 [old locus tag: SP_1207 ]
  • symbol: SP_RS05930
  • product: exodeoxyribonuclease VII large subunit
  • replicon: chromosome
  • strand: -
  • coordinates: 1139184..1140524
  • length: 1341
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: NC_003028 (1139184..1140524) NCBI
  • BioCyc: SP_RS05930 BioCyc
  • MicrobesOnline: see SP_1207
  • PneumoBrowse for strain D39V: SPV_1067 PneumoBrowse

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    ATGGAAAAGTATTTATCGGTAACAACTTTGACCAAGTATCTGAAAATGAAATTCGATAAA
    GACCCATACTTGGAACGGGTCTATTTAACTGGTCAAGTTTCCAACTTTCGTAAACGACCT
    ACTCACCAATATTTCTCCCTAAAGGATGACCATGCAGTTATTCAAGCGACCATCTGGTCT
    GGGATTTATCAGAAATTAGGGTTTGACCTGGAAGAAGGAATGAAGATCAATGTGATTGGG
    CGTGTACAGGTCTATGAACCAAGTGGTAGCTACTCCATCATCATTGAAAAAGCTGAGCCT
    GATGGGGTTGGGGCGCTTGCGATTCAGTTTGAACAACTTAAGAAAAAATTGACAGAAGAA
    GGCCTGTTTCAAGAACGCTTCAAGCAAGCTCTGCCCCAATTTTCTAAGAGAATTGGTGTA
    GTAACCAGCCGTAGTGGAGCCGTTATTCGAGATATTATCACGACCGTCAGCAGGCGATTC
    CCAGGTGTTGACATCCTTCTTTATCCGACCAAGGTTCAAGGTGAAGGGGCTGCGGAGGAA
    ATTGCTAGAAATATTGCGCGTGCTAATCAACGGGACGATTTGGATTTGCTCATTATTGGT
    CGTGGAGGTGGTTCTATTGAGGATCTCTGGGCCTTTAACGAAGAAATTGTGGTACGAGCT
    ATTTTTGAATCTCGTTTGCCAGTTATCTCTAGTGTGGGGCATGAGACGGATGTGACCTTG
    GCAGATTTTGTGGCAGATCGACGCGCTGCAACGCCAACAGCGGCGGCTGAACTGGCAACA
    CCTGTGACCAAGTTGGATGTATTAGCTCATTTGCAAAATCAGGAAAAACGGATGGTAACG
    GCAGTCCGAAATGTTCTATCTAAGAAACAAGAGGCTTTGAAAAAATGCAGTCAGTCTGTT
    ATCTTTAGACAACCTGAGCGCTTGTATGACGGTTATTTGCAACGCTTGGACCAACTGCAA
    CTGCGTTTGAAACAAAGTTTGCGAACTCGGATTTCTGATAACAAACAATTAGTTCAAGCA
    AGAACTCATCAATTAGTACAATTATCACCTGTTACCAAAATCCAACGCTATCAAGACCGT
    TTAGGACAGTTGGACAAGCTCTTAGGTAGCCAAATGGCGTTAGTTTATGACGCCAAGGTT
    GCTGAGGCCAAGCGACTTTCGGAAGCTTTGCTCATGTTGGATACTAGCCGAATCGTGGCG
    CGTGGTTATGCTATTGTCAAAAAAGAAGAGTCCGTTGTAGATTCGGTTGAGAGTTTGAAG
    AAAAAAGACCAAGTAACGCTTTTGATGCGAGATGGTCAAGTAGAATTAGAGGTTAAAGAT
    GTCAAAACAAAAGAAATTTGA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1341

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SP_RS05930 [old locus tag: SP_1207 ]
  • symbol: SP_RS05930
  • description: exodeoxyribonuclease VII large subunit
  • length: 446
  • theoretical pI: 9.87273
  • theoretical MW: 50507.9
  • GRAVY: -0.304933

⊟Function[edit | edit source]

  • ⊞⊞reaction:
    EC 3.1.11.6?  ExPASy
    Exodeoxyribonuclease VII Exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-direction to yield nucleoside 5'-phosphates
  • ⊞⊞TIGRFAM:
    Genetic information processing DNA metabolism Degradation of DNA exodeoxyribonuclease VII, large subunit (TIGR00237; EC 3.1.11.6; HMM-score: 476)
    and 1 more
    Genetic information processing Transcription Transcription factors RNA polymerase sigma factor RpoD (TIGR02393; HMM-score: 22.2)
  • TheSEED: see SP_1207
  • ⊞⊞PFAM:
    no clan defined Exonuc_VII_L; Exonuclease VII, large subunit (PF02601; HMM-score: 314.8)
    and 3 more
    OB (CL0021) tRNA_anti_2; OB-fold nucleic acid binding domain (PF13742; HMM-score: 84.9)
    tRNA_anti-codon; OB-fold nucleic acid binding domain (PF01336; HMM-score: 40.5)
    HROB; Homologous recombination OB-fold protein (PF15072; HMM-score: 13.4)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • ⊞⊞PSORTb: Cytoplasmic
    • Cytoplasmic Score: 9.97
    • Cytoplasmic Membrane Score: 0
    • Cellwall Score: 0.01
    • Extracellular Score: 0.02
    • Internal Helices: 0
  • ⊞⊞SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.002938
    • TAT(Tat/SPI): 0.000076
    • LIPO(Sec/SPII): 0.00039
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MEKYLSVTTLTKYLKMKFDKDPYLERVYLTGQVSNFRKRPTHQYFSLKDDHAVIQATIWSGIYQKLGFDLEEGMKINVIGRVQVYEPSGSYSIIIEKAEPDGVGALAIQFEQLKKKLTEEGLFQERFKQALPQFSKRIGVVTSRSGAVIRDIITTVSRRFPGVDILLYPTKVQGEGAAEEIARNIARANQRDDLDLLIIGRGGGSIEDLWAFNEEIVVRAIFESRLPVISSVGHETDVTLADFVADRRAATPTAAAELATPVTKLDVLAHLQNQEKRMVTAVRNVLSKKQEALKKCSQSVIFRQPERLYDGYLQRLDQLQLRLKQSLRTRISDNKQLVQARTHQLVQLSPVTKIQRYQDRLGQLDKLLGSQMALVYDAKVAEAKRLSEALLMLDTSRIVARGYAIVKKEESVVDSVESLKKKDQVTLLMRDGQVELEVKDVKTKEI

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Expression data[edit | edit source]

⊞Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊞Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

Retrieved from "http://pneumowiki.med.uni-greifswald.de/index.php?title=SP_RS05930&oldid=1164"
Insert paragraph

NCBI: 09-APR-2021

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae TIGR4
  • locus tag: SP_RS05930 [old locus tag: SP_1207 ]
  • pan locus tag?: PNEUPAN002471000
  • symbol: SP_RS05930
  • pan gene symbol?: xseA
  • synonym:
  • product: exodeoxyribonuclease VII large subunit

Insert paragraph

⊟Genome View[edit | edit source]

Insert paragraph

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SP_RS05930 [old locus tag: SP_1207 ]
  • symbol: SP_RS05930
  • product: exodeoxyribonuclease VII large subunit
  • replicon: chromosome
  • strand: -
  • coordinates: 1139184..1140524
  • length: 1341
  • essential: unknown

Insert paragraph

⊟Accession numbers[edit | edit source]

  • Location: NC_003028 (1139184..1140524) NCBI
  • BioCyc: SP_RS05930 BioCyc
  • MicrobesOnline: see SP_1207
  • PneumoBrowse for strain D39V: SPV_1067 PneumoBrowse

Insert paragraph

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    ATGGAAAAGTATTTATCGGTAACAACTTTGACCAAGTATCTGAAAATGAAATTCGATAAA
    GACCCATACTTGGAACGGGTCTATTTAACTGGTCAAGTTTCCAACTTTCGTAAACGACCT
    ACTCACCAATATTTCTCCCTAAAGGATGACCATGCAGTTATTCAAGCGACCATCTGGTCT
    GGGATTTATCAGAAATTAGGGTTTGACCTGGAAGAAGGAATGAAGATCAATGTGATTGGG
    CGTGTACAGGTCTATGAACCAAGTGGTAGCTACTCCATCATCATTGAAAAAGCTGAGCCT
    GATGGGGTTGGGGCGCTTGCGATTCAGTTTGAACAACTTAAGAAAAAATTGACAGAAGAA
    GGCCTGTTTCAAGAACGCTTCAAGCAAGCTCTGCCCCAATTTTCTAAGAGAATTGGTGTA
    GTAACCAGCCGTAGTGGAGCCGTTATTCGAGATATTATCACGACCGTCAGCAGGCGATTC
    CCAGGTGTTGACATCCTTCTTTATCCGACCAAGGTTCAAGGTGAAGGGGCTGCGGAGGAA
    ATTGCTAGAAATATTGCGCGTGCTAATCAACGGGACGATTTGGATTTGCTCATTATTGGT
    CGTGGAGGTGGTTCTATTGAGGATCTCTGGGCCTTTAACGAAGAAATTGTGGTACGAGCT
    ATTTTTGAATCTCGTTTGCCAGTTATCTCTAGTGTGGGGCATGAGACGGATGTGACCTTG
    GCAGATTTTGTGGCAGATCGACGCGCTGCAACGCCAACAGCGGCGGCTGAACTGGCAACA
    CCTGTGACCAAGTTGGATGTATTAGCTCATTTGCAAAATCAGGAAAAACGGATGGTAACG
    GCAGTCCGAAATGTTCTATCTAAGAAACAAGAGGCTTTGAAAAAATGCAGTCAGTCTGTT
    ATCTTTAGACAACCTGAGCGCTTGTATGACGGTTATTTGCAACGCTTGGACCAACTGCAA
    CTGCGTTTGAAACAAAGTTTGCGAACTCGGATTTCTGATAACAAACAATTAGTTCAAGCA
    AGAACTCATCAATTAGTACAATTATCACCTGTTACCAAAATCCAACGCTATCAAGACCGT
    TTAGGACAGTTGGACAAGCTCTTAGGTAGCCAAATGGCGTTAGTTTATGACGCCAAGGTT
    GCTGAGGCCAAGCGACTTTCGGAAGCTTTGCTCATGTTGGATACTAGCCGAATCGTGGCG
    CGTGGTTATGCTATTGTCAAAAAAGAAGAGTCCGTTGTAGATTCGGTTGAGAGTTTGAAG
    AAAAAAGACCAAGTAACGCTTTTGATGCGAGATGGTCAAGTAGAATTAGAGGTTAAAGAT
    GTCAAAACAAAAGAAATTTGA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1341

Insert paragraph

This data comes from external databases and cannot be edited.

Insert paragraph

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SP_RS05930 [old locus tag: SP_1207 ]
  • symbol: SP_RS05930
  • description: exodeoxyribonuclease VII large subunit
  • length: 446
  • theoretical pI: 9.87273
  • theoretical MW: 50507.9
  • GRAVY: -0.304933

Insert paragraph

⊟Function[edit | edit source]

  • ⊞reaction:
    EC 3.1.11.6?  ExPASy
    Exodeoxyribonuclease VII Exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-direction to yield nucleoside 5'-phosphates
  • ⊞TIGRFAM:
    Genetic information processing DNA metabolism Degradation of DNA exodeoxyribonuclease VII, large subunit (TIGR00237; EC 3.1.11.6; HMM-score: 476)
    and 1 more
    Genetic information processing Transcription Transcription factors RNA polymerase sigma factor RpoD (TIGR02393; HMM-score: 22.2)
  • TheSEED: see SP_1207
  • ⊞PFAM:
    no clan defined Exonuc_VII_L; Exonuclease VII, large subunit (PF02601; HMM-score: 314.8)
    and 3 more
    OB (CL0021) tRNA_anti_2; OB-fold nucleic acid binding domain (PF13742; HMM-score: 84.9)
    tRNA_anti-codon; OB-fold nucleic acid binding domain (PF01336; HMM-score: 40.5)
    HROB; Homologous recombination OB-fold protein (PF15072; HMM-score: 13.4)

Insert paragraph

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Insert paragraph

⊟Localization[edit | edit source]

  • ⊞PSORTb: Cytoplasmic
    • Cytoplasmic Score: 9.97
    • Cytoplasmic Membrane Score: 0
    • Cellwall Score: 0.01
    • Extracellular Score: 0.02
    • Internal Helices: 0
  • ⊞SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.002938
    • TAT(Tat/SPI): 0.000076
    • LIPO(Sec/SPII): 0.00039
  • predicted transmembrane helices (TMHMM): 0

Insert paragraph

⊟Accession numbers[edit | edit source]

Insert paragraph

⊟Protein sequence[edit | edit source]

  • MEKYLSVTTLTKYLKMKFDKDPYLERVYLTGQVSNFRKRPTHQYFSLKDDHAVIQATIWSGIYQKLGFDLEEGMKINVIGRVQVYEPSGSYSIIIEKAEPDGVGALAIQFEQLKKKLTEEGLFQERFKQALPQFSKRIGVVTSRSGAVIRDIITTVSRRFPGVDILLYPTKVQGEGAAEEIARNIARANQRDDLDLLIIGRGGGSIEDLWAFNEEIVVRAIFESRLPVISSVGHETDVTLADFVADRRAATPTAAAELATPVTKLDVLAHLQNQEKRMVTAVRNVLSKKQEALKKCSQSVIFRQPERLYDGYLQRLDQLQLRLKQSLRTRISDNKQLVQARTHQLVQLSPVTKIQRYQDRLGQLDKLLGSQMALVYDAKVAEAKRLSEALLMLDTSRIVARGYAIVKKEESVVDSVESLKKKDQVTLLMRDGQVELEVKDVKTKEI

Insert paragraph

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

Insert paragraph

⊟Expression & Regulation[edit | edit source]

Insert paragraph

⊟Operon[edit | edit source]

Insert paragraph

⊟Regulation[edit | edit source]

  • regulator:

Insert paragraph

⊟Expression data[edit | edit source]

Insert paragraph

⊞Biological Material[edit | edit source]

This data comes from external databases and cannot be edited.

This data comes from external databases and cannot be edited.

This data comes from external databases and cannot be edited.

This data comes from external databases and cannot be edited.

This data comes from external databases and cannot be edited.

This data comes from external databases and cannot be edited.

This data comes from external databases and cannot be edited.

⊞Other Information[edit | edit source]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

Insert paragraph

⊟Relevant publications[edit | edit source]

Insert paragraph