From PneumoWiki
Jump to navigation Jump to search
PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 31-JAN-2014

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae 670-6B
  • locus tag: SP670_1244 [new locus tag: SP670_RS06135 ]
  • pan locus tag?: PNEUPAN002235000
  • symbol: SP670_1244
  • pan gene symbol?: prs2
  • synonym:
  • product: ribose-Phosphate pyrophosphokinase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SP670_1244 [new locus tag: SP670_RS06135 ]
  • symbol: SP670_1244
  • product: ribose-Phosphate pyrophosphokinase
  • replicon: chromosome
  • strand: +
  • coordinates: 1170448..1171398
  • length: 951
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    ATGTCAGATAGAAAAAACATGAAACTTTTCGCACTCAACTCTAACCAAGAGATTGCACAA
    AAAATTGCCCAAGCTGTTGGTGTCCCACTTGGAAAACTATCATCACGTCAATTTTCAGAC
    GGAGAAATCCAAGTAAATATCGAAGAAAGTGTCCGTGGTTATGATGTTTACATCATCCAA
    TCAACAAGTTTCCCTGTCAACAACCACCTAATGGAATTGTTAATCATGGTCGATGCTTGT
    GTGCGTGCAAGTGCCCACAGTATCAACGTTGTCCTTCCATATTTTGGCTATGCACGTCAA
    GACCGCATTGCTTGTCCTCGTGAGCCACTTACAGCAAAACTAGTTGCCAATATGCTGGTT
    AAGGCTGGAGTTGATCGTATCCTGACTCTTGATTTGCATGCCGTTCAGGTTCAAGGTTTC
    TTTGATATTCCAGTGGATAATCTTTTCACTGTTCCCCTATTCGCAAAACATTACTGCGAT
    AAAGGATTGCTTGGTTCAGATGTTGTTGTCGTTAGCCCTAAAAATTCAGGTGTCAAACGT
    GCGCGTAGCCTGGCTGAATATCTTGATGCTCCTATCGCCATTATCGACTACCCTCAAGAC
    GATGCAACTCGTAACGAAGGTTATATTATTGGTGATGTTGAAGGTAAGAAAGCTATCTTG
    ATTGATGATATTTTAAATACAGGACGTACCTTCTCTGAAGCTTCTAAAATCGTTGAACGT
    GAAGGAGCTACAGAAATTTATGCTGTTTCTAGCCACGGTCTCTTCGTCGAGGGAGCTGCT
    GAGCTTCTTGACAATACTAATATTAAAGAAATTCTTGTGACTGATTCAGTAGCAACAAAA
    GAAAAAACTCCTAAAAATGTATGCTACATCACTGCTAGTGAGTTAATTGGTGATGCTATC
    GTCCGTATTCACGAAAGAAAAACCAGTCAGCCCACTCTTTGCCTACAATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    951

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SP670_1244 [new locus tag: SP670_RS06135 ]
  • symbol: SP670_1244
  • description: ribose-Phosphate pyrophosphokinase
  • length: 316
  • theoretical pI: 5.42754
  • theoretical MW: 34723.6
  • GRAVY:

⊟Function[edit | edit source]

  • ⊞reaction:
    EC 2.7.6.1?  ExPASy
    Ribose-phosphate diphosphokinase ATP + D-ribose 5-phosphate = AMP + 5-phospho-alpha-D-ribose 1-diphosphate
  • ⊞TIGRFAM:
    Metabolism Purines, pyrimidines, nucleosides, and nucleotides Purine ribonucleotide biosynthesis ribose-phosphate diphosphokinase (TIGR01251; EC 2.7.6.1; HMM-score: 336.2)
    and 6 more
    Cellular processes Cellular processes DNA transformation comF family protein (TIGR00201; HMM-score: 23.6)
    Metabolism Purines, pyrimidines, nucleosides, and nucleotides Pyrimidine ribonucleotide biosynthesis orotate phosphoribosyltransferase (TIGR01367; EC 2.4.2.10; HMM-score: 21.4)
    Metabolism Purines, pyrimidines, nucleosides, and nucleotides Pyrimidine ribonucleotide biosynthesis orotate phosphoribosyltransferase (TIGR00336; EC 2.4.2.10; HMM-score: 19)
    Metabolism Purines, pyrimidines, nucleosides, and nucleotides Salvage of nucleosides and nucleotides hypoxanthine phosphoribosyltransferase (TIGR01203; EC 2.4.2.8; HMM-score: 16.9)
    Metabolism Purines, pyrimidines, nucleosides, and nucleotides Salvage of nucleosides and nucleotides adenine phosphoribosyltransferase (TIGR01090; EC 2.4.2.7; HMM-score: 14.1)
    Metabolism Purines, pyrimidines, nucleosides, and nucleotides Salvage of nucleosides and nucleotides uracil phosphoribosyltransferase (TIGR01091; EC 2.4.2.9; HMM-score: 12.5)
  • ⊞TheSEED  :
    • Ribose-phosphate pyrophosphokinase (EC 2.7.6.1)
    Carbohydrates Central carbohydrate metabolism Pentose phosphate pathway  Ribose-phosphate pyrophosphokinase (EC 2.7.6.1)
    and 1 more
    Nucleosides and Nucleotides Purines De Novo Purine Biosynthesis  Ribose-phosphate pyrophosphokinase (EC 2.7.6.1)
  • ⊞PFAM:
    PRTase-like (CL0533) Pribosyltran_N; N-terminal domain of ribose phosphate pyrophosphokinase (PF13793; HMM-score: 165.1)
    and 4 more
    Pribosyl_synth; Phosphoribosyl synthetase-associated domain (PF14572; HMM-score: 79)
    Pribosyltran; Phosphoribosyl transferase domain (PF00156; HMM-score: 45)
    HAD (CL0137) Hydrolase_3; haloacid dehalogenase-like hydrolase (PF08282; HMM-score: 14.4)
    PRTase-like (CL0533) UPRTase; Uracil phosphoribosyltransferase (PF14681; HMM-score: 12.4)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • ⊞PSORTb: Cytoplasmic
    • Cytoplasmic Score: 9.67
    • Cytoplasmic Membrane Score: 0.01
    • Cellwall Score: 0.15
    • Extracellular Score: 0.17
    • Internal Helices: 0
  • ⊞DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.5452
    • Cytoplasmic Membrane Score: 0.0333
    • Cell wall & surface Score: 0.0009
    • Extracellular Score: 0.4207
  • ⊞SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.01365
    • TAT(Tat/SPI): 0.005901
    • LIPO(Sec/SPII): 0.001647
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: ADM91305 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MSDRKNMKLFALNSNQEIAQKIAQAVGVPLGKLSSRQFSDGEIQVNIEESVRGYDVYIIQSTSFPVNNHLMELLIMVDACVRASAHSINVVLPYFGYARQDRIACPREPLTAKLVANMLVKAGVDRILTLDLHAVQVQGFFDIPVDNLFTVPLFAKHYCDKGLLGSDVVVVSPKNSGVKRARSLAEYLDAPIAIIDYPQDDATRNEGYIIGDVEGKKAILIDDILNTGRTFSEASKIVEREGATEIYAVSSHGLFVEGAAELLDNTNIKEILVTDSVATKEKTPKNVCYITASELIGDAIVRIHERKTSQPTLCLQ

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Expression data[edit | edit source]

⊞Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊞Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

Retrieved from "http://pneumowiki.med.uni-greifswald.de/index.php?title=SP670_1244&oldid=21255"