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JJA
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NCTC7466
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serotype 3
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SPN994038
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SPN994039
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SPNA45
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TCH8431/19A
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serotype 19F
Xen35
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gamPNI0373
serotype 1

NCBI: 26-AUG-2017

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae OXC141
  • locus tag: SPNOXC08720 [new locus tag: SPNOXC_RS04730 ]
  • pan locus tag?: PNEUPAN001997000
  • symbol: fpg
  • pan gene symbol?: mutM
  • synonym:
  • product: formamidopyrimidine-DNA glycosylase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPNOXC08720 [new locus tag: SPNOXC_RS04730 ]
  • symbol: fpg
  • product: formamidopyrimidine-DNA glycosylase
  • replicon: chromosome
  • strand: +
  • coordinates: 882651..883475
  • length: 825
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    ATGCCTGAATTACCTGAGGTTGAAACCGTTTGTCGTAGCTTAGAAAAATTGATTATAGGA
    AAGAAGATTTCGAGTATAGAAATTCGCTACCCCAAGATGATTAAGACGGATTTGGAAGAG
    TTTCAAAGGGAATTGCCTAGTCAGATTATCGAGTCAATGGGACGTCGTGGAAAATATTTG
    CTTTTCTGCCTGACAGACAAGGTCTTGATTTCCCATTTGCGGATGGAGGGCAAGTATTTT
    TATTATCCAGACCAAGTGCCTGAACGCAAGCATGCCCATGTTTTCTTCCGGTTTGAAGAT
    GGGGGCACGCTTGTTTATGAGGATGTACGCAAGTTTGGAACCATGGAACTCTTGGTGCCT
    GACCTTTTAGACGCCTACTTTATTTCTAAAAAATTAGGTCCTGAACCAAGCGAACAAGAC
    TTTGATTTACAGGTCTTTCAAGCTGCCCTTGCCAAGTCCAAAAAGCCTATCAAATCCCAT
    CTCCTAGACCAGACCTTGGTAGCTGGACTTGGCAATATCTATGTGGATGAGGTTCTCTGG
    CGAGCTCAGGTTCATCCAGCTAGACCTTCCCAGACTTTGACAGCAGAAGAAGCGACTGCC
    ATTCATGACCAGACCATTGCTGTTTTGGGCCAGGCTGTTGAAAAAGGCGGTTCCACCATT
    CGGACCTATACCAATGCCTTTGGGGAAGATGGAAGCATGCAGGATTTTCATCAGGTCTAT
    GATAAGACTGGTCAAGAATGTGTACGCTGTGGTACCATCATTGAGAAAATTCAACTAGGC
    GGACGAGGCACCCACTTTTGTCCAAACTGTCAAAGGAGGGACTGA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    825

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPNOXC08720 [new locus tag: SPNOXC_RS04730 ]
  • symbol: Fpg
  • description: formamidopyrimidine-DNA glycosylase
  • length: 274
  • theoretical pI: 6.51215
  • theoretical MW: 31202.6
  • GRAVY: -0.364234

⊟Function[edit | edit source]

  • TIGRFAM:
    Genetic information processing DNA metabolism DNA replication, recombination, and repair DNA-formamidopyrimidine glycosylase (TIGR00577; EC 3.2.2.23; HMM-score: 343.9)
  • TheSEED  :
    • Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)
    DNA Metabolism DNA repair DNA Repair Base Excision  Formamidopyrimidine-DNA glycosylase (EC 3.2.2.23)
  • ⊞PFAM:
    H2TH (CL0303) H2TH; Formamidopyrimidine-DNA glycosylase H2TH domain (PF06831; HMM-score: 112.7)
    no clan defined Fapy_DNA_glyco; Formamidopyrimidine-DNA glycosylase N-terminal domain (PF01149; HMM-score: 111)
    and 4 more
    Zn_Beta_Ribbon (CL0167) zf-FPG_IleRS; Zinc finger found in FPG and IleRS (PF06827; HMM-score: 43.2)
    H2TH (CL0303) NFACT_N; NFACT N-terminal and middle domains (PF05833; HMM-score: 22.6)
    Zn_Beta_Ribbon (CL0167) OrfB_Zn_ribbon; Putative transposase DNA-binding domain (PF07282; HMM-score: 15.6)
    Zn-ribbon_8; Zinc ribbon domain (PF09723; HMM-score: 14.7)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • ⊞PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • ⊞SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.001859
    • TAT(Tat/SPI): 0.000212
    • LIPO(Sec/SPII): 0.000328
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: CBW32529 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MPELPEVETVCRSLEKLIIGKKISSIEIRYPKMIKTDLEEFQRELPSQIIESMGRRGKYLLFCLTDKVLISHLRMEGKYFYYPDQVPERKHAHVFFRFEDGGTLVYEDVRKFGTMELLVPDLLDAYFISKKLGPEPSEQDFDLQVFQAALAKSKKPIKSHLLDQTLVAGLGNIYVDEVLWRAQVHPARPSQTLTAEEATAIHDQTIAVLGQAVEKGGSTIRTYTNAFGEDGSMQDFHQVYDKTGQECVRCGTIIEKIQLGGRGTHFCPNCQRRD

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Expression data[edit | edit source]

⊞Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊞Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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