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PangenomeTIGR4
serotype 4
D39serotype 2
D39Vserotype 2
Hungary19A-6serotype 19A
EF3030serotype 19F
670-6Bserotype 6B
6A-10serotype 6A
70585serotype 5
A026serotype 19F
A66serotype 3
AP200serotype 11A
ASP0581serotype 12F
ATCC 49619serotype 19F
ATCC 700669serotype 23F
BVJ1JLserotype 1
CGSP14serotype 14
G54serotype 19F
HU-OHserotype 3
Hu15serotype 19A
Hu17serotype 19A
INV104serotype 1
INV200serotype 14
JJAserotype 14
MDRSPN001serotype 19F
NCTC7466serotype 2
NU83127serotype 4
OXC141serotype 3
P1031serotype 1
R6serotype 2
SP49serotype 19A
SPN032672serotype 1
SPN034156serotype 3
SPN034183serotype 3
SPN994038serotype 3
SPN994039serotype 3
SPNA45serotype 3
ST556serotype 19F
TCH8431/19Aserotype 19A
Taiwan19F-14serotype 19F
Xen35serotype 4
gamPNI0373serotype 1
NCBI: 30-JAN-2014
⊟Summary[edit | edit source]
- organism: Streptococcus pneumoniae R6
- locus tag: spr0530 [new locus tag: SPR_RS02685 ]
- pan locus tag?: PNEUPAN001546000
- symbol: fba
- pan gene symbol?: fba
- synonym:
- product: Fructose-bisphosphate aldolase
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS
- locus tag: spr0530 [new locus tag: SPR_RS02685 ]
- symbol: fba
- product: Fructose-bisphosphate aldolase
- replicon: chromosome
- strand: +
- coordinates: 529452..530333
- length: 882
- essential: yes [1] DEG other strains
⊟Accession numbers[edit | edit source]
- Location: AE007317 (529452..530333) NCBI
- BioCyc: SPR0530 BioCyc
- MicrobesOnline: 133415 MicrobesOnline
- PneumoBrowse for strain D39V: SPV_0526 PneumoBrowse
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
- 1
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841ATGGCAATCGTTTCAGCAGAAAAATTTGTCCAAGCAGCCCGTGACAACGGTTATGCAGTT
GGTGGATTTAACACAAACAACCTTGAGTGGACTCAAGCTATCTTGCGCGCAGCAGAAGCT
AAAAAAGCTCCAGTTTTGATCCAAACTTCAATGGGTGCTGCTAAATACATGGGTGGTTAC
AAAGTTGCTCGCAACTTGATCGCTAACCTTGTTGAATCAATGGGTATCACTGTACCAGTA
GCTATCCACCTTGACCACGGTCACTACGAAGATGCACTTGAGTGTATCGAAGTTGGTTAT
ACTTCAATCATGTTTGACGGTTCACACCTTCCAGTTGAAGAAAACCTTAAATTGGCTAAA
GAAGTTGTTGAAAAAGCACACGCTAAAGGTATCTCAGTAGAAGCTGAAGTTGGTACTATC
GGTGGTGAAGAAGACGGAATCATCGGTAAAGGTGAATTGGCTCCAATCGAAGACGCTAAA
GCAATGGTTGAAACTGGTATCGACTTCTTGGCAGCTGGTATCGGTAACATCCACGGCCCT
TACCCAGTAAACTGGGAAGGTCTTGACCTTGACCACTTGCAAAAATTGACAGAAGCTCTT
CCAGGATTCCCAATCGTATTGCACGGTGGATCAGGTATTCCTGATGAGCAAATCCAAGCA
GCTATCAAACTTGGTGTTGCCAAAGTTAACGTTAACACAGAATGCCAAATCGCATTCGCT
AACGCAACTCGTAAATTTGCTCGTGACTACGAAGCAAACGAAGCAGAATACGACAAGAAA
AAACTCTTCGACCCACGTAAATTCTTGGCTGACGGTGTAAAAGCTATCCAAGCATCGGTT
GAAGAACGTATCGACGTATTCGGTTCAGAAGGTAAAGCATAA60
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⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: spr0530 [new locus tag: SPR_RS02685 ]
- symbol: Fba
- description: Fructose-bisphosphate aldolase
- length: 293
- theoretical pI: 4.74308
- theoretical MW: 31401.5
- GRAVY: -0.078157
⊟Function[edit | edit source]
- ⊞reaction: EC 4.1.2.13? ExPASy
- ⊞TIGRFAM: Energy metabolism Glycolysis/gluconeogenesis fructose-1,6-bisphosphate aldolase, class II (TIGR01859; EC 4.1.2.13; HMM-score: 410.5)and 5 more
- ⊞TheSEED :
- Fructose-bisphosphate aldolase class II (EC 4.1.2.13)
Carbohydrates Central carbohydrate metabolism Glycolysis and Gluconeogenesis Fructose-bisphosphate aldolase class II (EC 4.1.2.13)and 1 more - ⊞PFAM: TIM_barrel (CL0036) F_bP_aldolase; Fructose-bisphosphate aldolase class-II (PF01116; HMM-score: 319.2)and 1 more
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
⊟Accession numbers[edit | edit source]
⊟Protein sequence[edit | edit source]
- MAIVSAEKFVQAARDNGYAVGGFNTNNLEWTQAILRAAEAKKAPVLIQTSMGAAKYMGGYKVARNLIANLVESMGITVPVAIHLDHGHYEDALECIEVGYTSIMFDGSHLPVEENLKLAKEVVEKAHAKGISVEAEVGTIGGEEDGIIGKGELAPIEDAKAMVETGIDFLAAGIGNIHGPYPVNWEGLDLDHLQKLTEALPGFPIVLHGGSGIPDEQIQAAIKLGVAKVNVNTECQIAFANATRKFARDYEANEAEYDKKKLFDPRKFLADGVKAIQASVEERIDVFGSEGKA
⊟Experimental data[edit | edit source]
- protein localization:
- interaction partners:
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
- MicrobesOnline: no polycistronic organisation predicted
⊟Expression data[edit | edit source]
- PneumoExpress for strain D39V: SPV_0526 PneumoExpress
⊞Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊞Other Information[edit | edit source]
⊟Literature[edit | edit source]
⊟References[edit | edit source]
- ↑ Jane A Thanassi, Sandra L Hartman-Neumann, Thomas J Dougherty, Brian A Dougherty, Michael J Pucci
Identification of 113 conserved essential genes using a high-throughput gene disruption system in Streptococcus pneumoniae.
Nucleic Acids Res: 2002, 30(14);3152-62
[PubMed:12136097] [WorldCat.org] [DOI] (I p)