⊟Summary[edit | edit source]

PangenomeTIGR4

serotype 4

D39

serotype 2

D39V

serotype 2

Hungary19A-6

serotype 19A

EF3030

serotype 19F

670-6B

serotype 6B

6A-10

serotype 6A

70585

serotype 5

A026

serotype 19F

A66

serotype 3

AP200

serotype 11A

ASP0581

serotype 12F

ATCC 49619

serotype 19F

ATCC 700669

serotype 23F

BVJ1JL

serotype 1

CGSP14

serotype 14

G54

serotype 19F

HU-OH

serotype 3

Hu15

serotype 19A

Hu17

serotype 19A

INV104

serotype 1

INV200

serotype 14

JJA

serotype 14

MDRSPN001

serotype 19F

NCTC7466

serotype 2

NU83127

serotype 4

OXC141

serotype 3

P1031

serotype 1

R6

serotype 2

SP49

serotype 19A

SPN032672

serotype 1

SPN034156

serotype 3

SPN034183

serotype 3

SPN994038

serotype 3

SPN994039

serotype 3

SPNA45

serotype 3

ST556

serotype 19F

TCH8431/19A

serotype 19A

Taiwan19F-14

serotype 19F

Xen35

serotype 4

gamPNI0373

serotype 1

NCBI: 30-JAN-2014

⊟Summary

• organism: Streptococcus pneumoniae R6
locus tag: spr1725 [new locus tag: SPR_RS08690 ]
pan locus tag^?: PNEUPAN003502000
symbol: ydfG
pan gene symbol^?: ydfG
• synonym:
• product: Oxidoreductase

⊟Genome View

⊟Gene

⊟General

• type: CDS
• locus tag: spr1725 [new locus tag: SPR_RS08690 ]
• symbol: ydfG
• product: Oxidoreductase
• replicon: chromosome
• strand: -
• coordinates: 1704954..1705715
• length: 762
• essential: unknown

⊟Accession numbers

• Location: AE007317 (1704954..1705715) NCBI
• BioCyc: SPR1725 BioCyc
• MicrobesOnline: 134608 MicrobesOnline
• PneumoBrowse for strain D39V: SPV_1712 PneumoBrowse

⊟Phenotype

Share your knowledge and add information here. [edit]

⊟DNA sequence

• 1
  61
  121
  181
  241
  301
  361
  421
  481
  541
  601
  661
  721
  
  ATGGCAAAAAATGTAGTGATTACGGGAGCAACCTCAGGAATCGGTGAAGCGATTGCGCGT
  GCTTATCTGGAGCAGGGTGAGGATGTCGTTCTAACAGGACGACGGATAGACAGATTAGAA
  ATCCTCAAGTCGGAGTTTGCAGTAAGCTTTCCAAATCAAACCGTCTGGACTTTTCCACTA
  GATGTGACGGATATGGTCATGGTGAAGACTGTTTGCTCTGATATTCTAGAAACGATAGGG
  AGGATTGATATCTTGGTCAACAACGCCGGACTGGCTCTTGACTTGGCTCCCTATCAAGAC
  TATGAGGAGTTGGATATGTTGACCATGTTGGATACCAATGTTAAAGGTCTGATGGCGGTT
  ACTCACTGTTTCTTGCCAGCAATGATAAAAGTCAATCAAGGTCATATTATCAATATGGGG
  TCAACCGCAGGAATCTACGCCTATGCTGGTGCCGCTGTTTACTCAGCTACCAAGGCAGCG
  GTTAAGACCTTTTCGGATGGACTGCGAATTGATACCATCGCAACGGATATCAAGGTGACA
  ACCATTCAGCCTGGGATTGTCGAAACAGATTTCTCAACTGTTCGTTTTCATGGTGATAAA
  GAACGAGCTGCGTCCGTTTACCAAGGAATAGAAGCCTTGCAAGCTCAGGATATTGCAGAC
  ACAGTAGTCTATGTGACCAGTCAGCCTCGCCGTGTTCAGATTACAGATATGACCATTATG
  GCCAATCAACAGGCGACAGGTTTCATGATTCATAAAAAATAA
  60
  120
  180
  240
  300
  360
  420
  480
  540
  600
  660
  720
  762
  

⊟Protein

⊟General

• locus tag: spr1725 [new locus tag: SPR_RS08690 ]
• symbol: YdfG
• description: Oxidoreductase
• length: 253
• theoretical pI: 4.77805
• theoretical MW: 27574.6
• GRAVY: 0.159684

⊟Function

• reaction:
  EC 1.-.-.-?  ExPASy
• ⊞⊞TIGRFAM:
  Metabolism Fatty acid and phospholipid metabolism Biosynthesis 3-oxoacyl-[acyl-carrier-protein] reductase (TIGR01830; EC 1.1.1.100; HMM-score: 122.3)
  3-hydroxybutyrate dehydrogenase (TIGR01963; HMM-score: 119.8)
  2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase (TIGR04316; EC 1.3.1.28; HMM-score: 108.5)
  acetoacetyl-CoA reductase (TIGR01829; EC 1.1.1.36; HMM-score: 101.7)
  and 13 more
  Unknown function Enzymes of unknown specificity SDR family mycofactocin-dependent oxidoreductase (TIGR03971; EC 1.1.99.-; HMM-score: 95.7)
  Metabolism Energy metabolism Biosynthesis and degradation of polysaccharides 2-deoxy-D-gluconate 3-dehydrogenase (TIGR01832; EC 1.1.1.125; HMM-score: 90.9)
  Metabolism Energy metabolism Fermentation acetoin reductases (TIGR02415; EC 1.1.1.-; HMM-score: 86)
  2-hydroxycyclohexanecarboxyl-CoA dehydrogenase (TIGR03206; EC 1.1.1.-; HMM-score: 81.6)
  Unknown function Enzymes of unknown specificity SDR family mycofactocin-dependent oxidoreductase (TIGR04504; EC 1.1.99.-; HMM-score: 77.2)
  rhamnulose-1-phosphate aldolase/alcohol dehydrogenase (TIGR02632; EC 1.1.1.1,4.1.2.19; HMM-score: 76.1)
  Metabolism Fatty acid and phospholipid metabolism Biosynthesis putative 3-oxoacyl-(acyl-carrier-protein) reductase (TIGR01831; HMM-score: 71.7)
  cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase (TIGR03325; EC 1.3.1.56; HMM-score: 62)
  sepiapterin reductase (TIGR01500; EC 1.1.1.153; HMM-score: 58.4)
  pteridine reductase (TIGR02685; EC 1.5.1.33; HMM-score: 38.9)
  Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Chlorophyll and bacteriochlorphyll light-dependent protochlorophyllide reductase (TIGR01289; EC 1.3.1.33; HMM-score: 32.4)
  Metabolism Central intermediary metabolism Other long-chain fatty acyl-ACP reductase (aldehyde-forming) (TIGR04058; EC 1.1.1.-; HMM-score: 18.7)
  hopanoid-associated sugar epimerase (TIGR03466; HMM-score: 12.5)
• TheSEED  :
  • Oxidoreductase, short-chain dehydrogenase/reductase family
• ⊞⊞PFAM:
  NADP_Rossmann (CL0063) adh_short; short chain dehydrogenase (PF00106; HMM-score: 172.3)
  and 3 more
  adh_short_C2; Enoyl-(Acyl carrier protein) reductase (PF13561; HMM-score: 126.7)
  KR; KR domain (PF08659; HMM-score: 43.5)
  Epimerase; NAD dependent epimerase/dehydratase family (PF01370; HMM-score: 15.5)

⊟Structure, modifications & cofactors

• domains:
• modifications:
• cofactors:
• effectors:

⊟Localization

• ⊞⊞PSORTb: Cytoplasmic
  • Cytoplasmic Score: 9.97
  • Cytoplasmic Membrane Score: 0
  • Cellwall Score: 0.01
  • Extracellular Score: 0.02
  • Internal Helices: 0
• ⊞⊞SignalP: no predicted signal peptide
  • SP(Sec/SPI): 0.010163
  • TAT(Tat/SPI): 0.000551
  • LIPO(Sec/SPII): 0.001098
• predicted transmembrane helices (TMHMM): 0

⊟Accession numbers

• GI:
• RefSeq: AAL00528 NCBI
• UniProt: Q8DNH3 UniProt

⊟Protein sequence

• MAKNVVITGATSGIGEAIARAYLEQGEDVVLTGRRIDRLEILKSEFAVSFPNQTVWTFPLDVTDMVMVKTVCSDILETIGRIDILVNNAGLALDLAPYQDYEELDMLTMLDTNVKGLMAVTHCFLPAMIKVNQGHIINMGSTAGIYAYAGAAVYSATKAAVKTFSDGLRIDTIATDIKVTTIQPGIVETDFSTVRFHGDKERAASVYQGIEALQAQDIADTVVYVTSQPRRVQITDMTIMANQQATGFMIHKK

⊟Experimental data

• protein localization:
• interaction partners:

⊟Expression & Regulation

⊟Operon

• MicrobesOnline: ydfG < spr1726 < spr1727 < spr1728

⊟Regulation

• regulator:

⊟Expression data

• PneumoExpress for strain D39V: SPV_1712 PneumoExpress

⊞Biological Material

⊟Mutants

⊟Expression vector

⊟lacZ fusion

⊟GFP fusion

⊟two-hybrid system

⊟FLAG-tag construct

⊟Antibody

⊞Other Information

You are kindly invited to share additional interesting facts.

⊟Literature

⊟References

⊟Relevant publications