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From PneumoWiki
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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 11-FEB-2025

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae INV200
  • locus tag: SPNINV200_RS05935 [old locus tag: SPNINV200_11080 ]
  • pan locus tag?: PNEUPAN002237000
  • symbol: SPNINV200_RS05935
  • pan gene symbol?: yjbM
  • synonym:
  • product: GTP pyrophosphokinase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPNINV200_RS05935 [old locus tag: SPNINV200_11080 ]
  • symbol: SPNINV200_RS05935
  • product: GTP pyrophosphokinase
  • replicon: chromosome
  • strand: -
  • coordinates: 1139921..1140592
  • length: 672
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

  • Location: NC_017593 (1139921..1140592) NCBI
  • BioCyc: SPNINV200_RS05935 BioCyc
  • MicrobesOnline:
  • PneumoBrowse for strain D39V: SPV_0982 PneumoBrowse

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    ATGACCTTAGAATGGGAAGAATTTCTAGATCCTTACATTCAAGCTGTTGGTGAGTTAAAG
    ATTAAACTTCGTGGTATTCGTAAGCAATATCGTAAGCAAAATAAGCATTCTCCAATTGAG
    TTTGTGACCGGTCGAGTCAAGCCAATTGAGAGCATCAAAGAAAAAATGGCTCGTCGTGGC
    ATTACTTATGCGACCTTGGAACACGATTTGCAGGATATTGCTGGCTTACGTGTGATGGTT
    CAGTTTGTAGATGACGTCAAGGAAGTAGTGGATATTTTGCACAAGCGTCAGGATATGCGA
    ATCATACAGGAGCGAGATTACATTACTCATAGAAAAGCATCAGGCTATCGTTCCTATCAT
    GTGGTAGTAGAATATACGGTTGATACCATCAATGGAGCTAAGACTATTTTGGCAGAAATT
    CAAATTCGTACTTTGGCCATGAATTTCTGGGCAACGATAGAACATTCTCTCAACTACAAG
    TACCAAGGGGATTTCCCAGATGAGATTAAGAAGCGACTGGAAATTACAGCTAGAATCGCC
    CATCAGTTGGATGAAGAAATGGGTGAAATTCGTGATGATATCCAAGAAGCTCAGGCACTT
    TTTGATCCTTTGAGTAGAAAATTAAATGACGGTGTAGGAAACAGTGACGATACAGATGAA
    GAATACAGGTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    672

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPNINV200_RS05935 [old locus tag: SPNINV200_11080 ]
  • symbol: SPNINV200_RS05935
  • description: GTP pyrophosphokinase
  • length: 223
  • theoretical pI: 5.9297
  • theoretical MW: 26182.6
  • GRAVY: -0.626906

⊟Function[edit | edit source]

  • ⊞⊞reaction:
    EC 2.7.6.5?  ExPASy
    GTP diphosphokinase ATP + GTP = AMP + guanosine 3'-diphosphate 5'-triphosphate
  • ⊞⊞TIGRFAM:
    Cellular processes Cellular processes Adaptations to atypical conditions RelA/SpoT family protein (TIGR00691; HMM-score: 51.4)
    and 1 more
    WXG100 family type VII secretion target (TIGR03930; HMM-score: 12.3)
  • TheSEED: see SPNINV200_11080
  • ⊞⊞PFAM:
    NTP_transf (CL0260) RelA_SpoT; Region found in RelA / SpoT proteins (PF04607; HMM-score: 131.6)
    and 3 more
    no clan defined COG2_C; COG complex component, COG2, C-terminal (PF12022; HMM-score: 21.6)
    HTH (CL0123) DUF6471; Domain of unknown function (DUF6471) (PF20075; HMM-score: 16.6)
    no clan defined HSL_N; Hormone-sensitive lipase (HSL) N-terminus (PF06350; HMM-score: 13)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • ⊞⊞PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • ⊞⊞DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.9778
    • Cytoplasmic Membrane Score: 0.0095
    • Cell wall & surface Score: 0.0003
    • Extracellular Score: 0.0124
  • ⊞⊞SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.002446
    • TAT(Tat/SPI): 0.000248
    • LIPO(Sec/SPII): 0.000725
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_000171676 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MTLEWEEFLDPYIQAVGELKIKLRGIRKQYRKQNKHSPIEFVTGRVKPIESIKEKMARRGITYATLEHDLQDIAGLRVMVQFVDDVKEVVDILHKRQDMRIIQERDYITHRKASGYRSYHVVVEYTVDTINGAKTILAEIQIRTLAMNFWATIEHSLNYKYQGDFPDEIKKRLEITARIAHQLDEEMGEIRDDIQEAQALFDPLSRKLNDGVGNSDDTDEEYR

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

⊟Expression data[edit | edit source]

⊞Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊞Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

Retrieved from "http://pneumowiki.med.uni-greifswald.de/index.php?title=SPNINV200_RS05935&oldid=97935"
Insert paragraph

NCBI: 11-FEB-2025

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae INV200
  • locus tag: SPNINV200_RS05935 [old locus tag: SPNINV200_11080 ]
  • pan locus tag?: PNEUPAN002237000
  • symbol: SPNINV200_RS05935
  • pan gene symbol?: yjbM
  • synonym:
  • product: GTP pyrophosphokinase

Insert paragraph

⊟Genome View[edit | edit source]

Insert paragraph

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPNINV200_RS05935 [old locus tag: SPNINV200_11080 ]
  • symbol: SPNINV200_RS05935
  • product: GTP pyrophosphokinase
  • replicon: chromosome
  • strand: -
  • coordinates: 1139921..1140592
  • length: 672
  • essential: unknown other strains

Insert paragraph

⊟Accession numbers[edit | edit source]

  • Location: NC_017593 (1139921..1140592) NCBI
  • BioCyc: SPNINV200_RS05935 BioCyc
  • MicrobesOnline:
  • PneumoBrowse for strain D39V: SPV_0982 PneumoBrowse

Insert paragraph

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    ATGACCTTAGAATGGGAAGAATTTCTAGATCCTTACATTCAAGCTGTTGGTGAGTTAAAG
    ATTAAACTTCGTGGTATTCGTAAGCAATATCGTAAGCAAAATAAGCATTCTCCAATTGAG
    TTTGTGACCGGTCGAGTCAAGCCAATTGAGAGCATCAAAGAAAAAATGGCTCGTCGTGGC
    ATTACTTATGCGACCTTGGAACACGATTTGCAGGATATTGCTGGCTTACGTGTGATGGTT
    CAGTTTGTAGATGACGTCAAGGAAGTAGTGGATATTTTGCACAAGCGTCAGGATATGCGA
    ATCATACAGGAGCGAGATTACATTACTCATAGAAAAGCATCAGGCTATCGTTCCTATCAT
    GTGGTAGTAGAATATACGGTTGATACCATCAATGGAGCTAAGACTATTTTGGCAGAAATT
    CAAATTCGTACTTTGGCCATGAATTTCTGGGCAACGATAGAACATTCTCTCAACTACAAG
    TACCAAGGGGATTTCCCAGATGAGATTAAGAAGCGACTGGAAATTACAGCTAGAATCGCC
    CATCAGTTGGATGAAGAAATGGGTGAAATTCGTGATGATATCCAAGAAGCTCAGGCACTT
    TTTGATCCTTTGAGTAGAAAATTAAATGACGGTGTAGGAAACAGTGACGATACAGATGAA
    GAATACAGGTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    672

Insert paragraph

This data comes from external databases and cannot be edited.

Insert paragraph

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPNINV200_RS05935 [old locus tag: SPNINV200_11080 ]
  • symbol: SPNINV200_RS05935
  • description: GTP pyrophosphokinase
  • length: 223
  • theoretical pI: 5.9297
  • theoretical MW: 26182.6
  • GRAVY: -0.626906

Insert paragraph

⊟Function[edit | edit source]

  • ⊞reaction:
    EC 2.7.6.5?  ExPASy
    GTP diphosphokinase ATP + GTP = AMP + guanosine 3'-diphosphate 5'-triphosphate
  • ⊞TIGRFAM:
    Cellular processes Cellular processes Adaptations to atypical conditions RelA/SpoT family protein (TIGR00691; HMM-score: 51.4)
    and 1 more
    WXG100 family type VII secretion target (TIGR03930; HMM-score: 12.3)
  • TheSEED: see SPNINV200_11080
  • ⊞PFAM:
    NTP_transf (CL0260) RelA_SpoT; Region found in RelA / SpoT proteins (PF04607; HMM-score: 131.6)
    and 3 more
    no clan defined COG2_C; COG complex component, COG2, C-terminal (PF12022; HMM-score: 21.6)
    HTH (CL0123) DUF6471; Domain of unknown function (DUF6471) (PF20075; HMM-score: 16.6)
    no clan defined HSL_N; Hormone-sensitive lipase (HSL) N-terminus (PF06350; HMM-score: 13)

Insert paragraph

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Insert paragraph

⊟Localization[edit | edit source]

  • ⊞PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • ⊞DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.9778
    • Cytoplasmic Membrane Score: 0.0095
    • Cell wall & surface Score: 0.0003
    • Extracellular Score: 0.0124
  • ⊞SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.002446
    • TAT(Tat/SPI): 0.000248
    • LIPO(Sec/SPII): 0.000725
  • predicted transmembrane helices (TMHMM): 0

Insert paragraph

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_000171676 NCBI
  • UniProt:

Insert paragraph

⊟Protein sequence[edit | edit source]

  • MTLEWEEFLDPYIQAVGELKIKLRGIRKQYRKQNKHSPIEFVTGRVKPIESIKEKMARRGITYATLEHDLQDIAGLRVMVQFVDDVKEVVDILHKRQDMRIIQERDYITHRKASGYRSYHVVVEYTVDTINGAKTILAEIQIRTLAMNFWATIEHSLNYKYQGDFPDEIKKRLEITARIAHQLDEEMGEIRDDIQEAQALFDPLSRKLNDGVGNSDDTDEEYR

Insert paragraph

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

Insert paragraph

⊟Expression & Regulation[edit | edit source]

Insert paragraph

⊟Operon[edit | edit source]

Insert paragraph

⊟Regulation[edit | edit source]

Insert paragraph

⊟Expression data[edit | edit source]

Insert paragraph

⊞Biological Material[edit | edit source]

This data comes from external databases and cannot be edited.

This data comes from external databases and cannot be edited.

This data comes from external databases and cannot be edited.

This data comes from external databases and cannot be edited.

This data comes from external databases and cannot be edited.

This data comes from external databases and cannot be edited.

This data comes from external databases and cannot be edited.

⊞Other Information[edit | edit source]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

Insert paragraph

⊟Relevant publications[edit | edit source]

Insert paragraph