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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: SPV_1845 [new locus tag: SPV_RS09815 ]
  • symbol: ulaC
  • product: Ascorbate-specific PTS IIA component
  • replicon: chromosome
  • strand: -
  • coordinates: 1831340..1831825
  • length: 486
  • essential: unknown

Accession numbers[edit | edit source]

  • Location: CP027540 (1831340..1831825) NCBI
  • BioCyc: SPV_1845 BioCyc
  • MicrobesOnline:
  • PneumoBrowse: SPV_1845 PneumoBrowse

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    ATGAATTTAAAACAAGCTTTAATTGACAATGACTCGATCCGACTAGGTTTAGAGGCTAAC
    AATTGGAAAGAAGCAGTCAAGGTAGCAGTAGATCCCTTAATTGAAAGTGGGGCAATTTTG
    CCAGAGTATTACGATGCTATCATTGAATCGACTGAAGAGTATGGGCCTTACTATATCTTG
    ATGCCAGGTATGGCTATGCCCCACGCTAGACCTGAAGCTGGTGTGCAAAGTGATGCCTTT
    TCATTGATTACCTTACAAAATCCTGTTGTATTTTCAGATGGGAAAGAGGTATCTGTTTTG
    TTGGCACTAGCAGCAACAAGCTCAAAAATTCACACAAGTGTAGCCATTCCACAAATTATT
    GCCCTGTTTGAATTAGAAGATTCTATTGCACGTTTACAGGCTTGCCAGACTAAAGAAGAT
    GTCTTGGCTATGATTGAAGAATCTAAGGATAGCCCTTATCTCGAAGGATTGGATTTGGAA
    AGTTAG
    60
    120
    180
    240
    300
    360
    420
    480
    486

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: SPV_1845 [new locus tag: SPV_RS09815 ]
  • symbol: UlaC
  • description: Ascorbate-specific PTS IIA component
  • length: 161
  • theoretical pI: 3.97522
  • theoretical MW: 17582.9
  • GRAVY: 0.078882

Function[edit | edit source]

  • reaction:
    EC 2.7.1.194?  ExPASy
    Protein-N(pi)-phosphohistidine--L-ascorbate phosphotransferase [Protein]-N(pi)-phospho-L-histidine + L-ascorbate(Side 1) = [protein]-L-histidine + L-ascorbate 6-phosphate(Side 2)
  • TIGRFAM:
    Signal transduction Signal transduction PTS PTS IIA-like nitrogen-regulatory protein PtsN (TIGR01419; HMM-score: 21.1)
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids PTS system, fructose subfamily, IIA component (TIGR00848; EC 2.7.1.69; HMM-score: 17)
    Signal transduction Signal transduction PTS PTS system, fructose subfamily, IIA component (TIGR00848; EC 2.7.1.69; HMM-score: 17)
  • TheSEED: data available for D39, Hungary19A-6, TIGR4
  • PFAM:
    PTase-anion_tr (CL0340) PTS_EIIA_2; Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 (PF00359; HMM-score: 111.9)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.9987
    • Cytoplasmic Membrane Score: 0.0003
    • Cell wall & surface Score: 0
    • Extracellular Score: 0.001
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.004829
    • TAT(Tat/SPI): 0.000288
    • LIPO(Sec/SPII): 0.0005
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit | edit source]

  • GI:
  • RefSeq: AVN86870 NCBI
  • UniProt:

Protein sequence[edit | edit source]

  • MNLKQALIDNDSIRLGLEANNWKEAVKVAVDPLIESGAILPEYYDAIIESTEEYGPYYILMPGMAMPHARPEAGVQSDAFSLITLQNPVVFSDGKEVSVLLALAATSSKIHTSVAIPQIIALFELEDSIARLQACQTKEDVLAMIEESKDSPYLEGLDLES

Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Expression data[edit | edit source]

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]

NCBI: 06-SEP-2024

Summary[edit | edit source]

  • organism: Streptococcus pneumoniae D39V
  • locus tag: SPV_1845 [new locus tag: SPV_RS09815 ]
  • pan locus tag?: PNEUPAN003669000
  • symbol: ulaC
  • pan gene symbol?: ulaC
  • synonym:
  • product: Ascorbate-specific PTS IIA component

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: SPV_1845 [new locus tag: SPV_RS09815 ]
  • symbol: ulaC
  • product: Ascorbate-specific PTS IIA component
  • replicon: chromosome
  • strand: -
  • coordinates: 1831340..1831825
  • length: 486
  • essential: unknown

Accession numbers[edit | edit source]

  • Location: CP027540 (1831340..1831825) NCBI
  • BioCyc: SPV_1845 BioCyc
  • MicrobesOnline:
  • PneumoBrowse: SPV_1845 PneumoBrowse

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    ATGAATTTAAAACAAGCTTTAATTGACAATGACTCGATCCGACTAGGTTTAGAGGCTAAC
    AATTGGAAAGAAGCAGTCAAGGTAGCAGTAGATCCCTTAATTGAAAGTGGGGCAATTTTG
    CCAGAGTATTACGATGCTATCATTGAATCGACTGAAGAGTATGGGCCTTACTATATCTTG
    ATGCCAGGTATGGCTATGCCCCACGCTAGACCTGAAGCTGGTGTGCAAAGTGATGCCTTT
    TCATTGATTACCTTACAAAATCCTGTTGTATTTTCAGATGGGAAAGAGGTATCTGTTTTG
    TTGGCACTAGCAGCAACAAGCTCAAAAATTCACACAAGTGTAGCCATTCCACAAATTATT
    GCCCTGTTTGAATTAGAAGATTCTATTGCACGTTTACAGGCTTGCCAGACTAAAGAAGAT
    GTCTTGGCTATGATTGAAGAATCTAAGGATAGCCCTTATCTCGAAGGATTGGATTTGGAA
    AGTTAG
    60
    120
    180
    240
    300
    360
    420
    480
    486

This data comes from external databases and cannot be edited.

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: SPV_1845 [new locus tag: SPV_RS09815 ]
  • symbol: UlaC
  • description: Ascorbate-specific PTS IIA component
  • length: 161
  • theoretical pI: 3.97522
  • theoretical MW: 17582.9
  • GRAVY: 0.078882

Function[edit | edit source]

  • reaction:
    EC 2.7.1.194?  ExPASy
    Protein-N(pi)-phosphohistidine--L-ascorbate phosphotransferase [Protein]-N(pi)-phospho-L-histidine + L-ascorbate(Side 1) = [protein]-L-histidine + L-ascorbate 6-phosphate(Side 2)
  • TIGRFAM:
    Signal transduction Signal transduction PTS PTS IIA-like nitrogen-regulatory protein PtsN (TIGR01419; HMM-score: 21.1)
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids PTS system, fructose subfamily, IIA component (TIGR00848; EC 2.7.1.69; HMM-score: 17)
    Signal transduction Signal transduction PTS PTS system, fructose subfamily, IIA component (TIGR00848; EC 2.7.1.69; HMM-score: 17)
  • TheSEED: data available for D39, Hungary19A-6, TIGR4
  • PFAM:
    PTase-anion_tr (CL0340) PTS_EIIA_2; Phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 (PF00359; HMM-score: 111.9)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.9987
    • Cytoplasmic Membrane Score: 0.0003
    • Cell wall & surface Score: 0
    • Extracellular Score: 0.001
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.004829
    • TAT(Tat/SPI): 0.000288
    • LIPO(Sec/SPII): 0.0005
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit | edit source]

  • GI:
  • RefSeq: AVN86870 NCBI
  • UniProt:

Protein sequence[edit | edit source]

  • MNLKQALIDNDSIRLGLEANNWKEAVKVAVDPLIESGAILPEYYDAIIESTEEYGPYYILMPGMAMPHARPEAGVQSDAFSLITLQNPVVFSDGKEVSVLLALAATSSKIHTSVAIPQIIALFELEDSIARLQACQTKEDVLAMIEESKDSPYLEGLDLES

Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

  • regulator:

Expression data[edit | edit source]

Biological Material[edit | edit source]

This data comes from external databases and cannot be edited.

This data comes from external databases and cannot be edited.

This data comes from external databases and cannot be edited.

This data comes from external databases and cannot be edited.

This data comes from external databases and cannot be edited.

This data comes from external databases and cannot be edited.

This data comes from external databases and cannot be edited.

Other Information[edit | edit source]

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]