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NCBI: 17-JAN-2018

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae AP200
  • locus tag: SPAP_1219 [new locus tag: SPAP_RS06025 ]
  • pan locus tag?: PNEUPAN002457000
  • symbol: SPAP_1219
  • pan gene symbol?: lacB
  • synonym:
  • product: Ribose 5-phosphate isomerase RpiB

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPAP_1219 [new locus tag: SPAP_RS06025 ]
  • symbol: SPAP_1219
  • product: Ribose 5-phosphate isomerase RpiB
  • replicon: chromosome
  • strand: -
  • coordinates: 1158951..1159466
  • length: 516
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    ATGAGAATTGCAATTGGATGTGACCACATCGTAACTGATGAAAAAATGGCGGTTTCAGAA
    TTTTTGAAATCAAAAGGATATGAAGTCATTGACTTTGGTACCTATGACCATACACGGACT
    CACTACCCAATCTTTGGTAAAAAAGTAGGGGAAGCAGTAACTAGTGGTCAAGCTGATCTC
    GGGGTATGTATCTGTGGTACTGGTGTTGGTATCAACAACGCTGTAAATAAAGTTCCAGGT
    GTTCGTTCTGCCTTGGTTCGTGATATGACAACAGCCCTTTATGCTAAAGAACAATTGAAC
    GCCAACGTTATCGGTTTTGGTGGTAAGATTACTGGTGAATTGCTTATGTGTGATATCATC
    GAAGCTTTCATTCATGCTGAATACAAACCATCTGAAGAAAACAAAAAATTGATTGCGAAA
    ATTGAACACCATGAAAGTCACAATGCTCAACAAACAGACGCAAACTTCTTCACTGAATTC
    CTTGAAAAATGGGATCGCGGAGAATACCACGACTAA
    60
    120
    180
    240
    300
    360
    420
    480
    516

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPAP_1219 [new locus tag: SPAP_RS06025 ]
  • symbol: SPAP_1219
  • description: Ribose 5-phosphate isomerase RpiB
  • length: 171
  • theoretical pI: 5.82338
  • theoretical MW: 18981.4
  • GRAVY: -0.280117

⊟Function[edit | edit source]

  • ⊞TIGRFAM:
    Metabolism Energy metabolism Biosynthesis and degradation of polysaccharides galactose-6-phosphate isomerase, LacB subunit (TIGR01119; EC 5.3.1.26; HMM-score: 353.4)
    and 6 more
    sugar-phosphate isomerase, RpiB/LacA/LacB family (TIGR00689; EC 5.3.1.-; HMM-score: 120.3)
    Metabolism Energy metabolism Pentose phosphate pathway ribose 5-phosphate isomerase B (TIGR01120; EC 5.3.1.6; HMM-score: 117.2)
    ribose 5-phosphate isomerase (TIGR02133; EC 5.3.1.6; HMM-score: 101.7)
    Metabolism Energy metabolism Biosynthesis and degradation of polysaccharides galactose-6-phosphate isomerase, LacA subunit (TIGR01118; EC 5.3.1.26; HMM-score: 45.1)
    Hypothetical proteins Conserved conserved hypothetical protein EF_0830/AHA_3911 (TIGR03577; HMM-score: 15.9)
    methyltransferase cognate corrinoid proteins, Methanosarcina family (TIGR02370; HMM-score: 12.7)
  • TheSEED  :
    • Galactose-6-phosphate isomerase, LacB subunit (EC 5.3.1.26)
    Carbohydrates Di- and oligosaccharides Lactose and Galactose Uptake and Utilization  Galactose-6-phosphate isomerase, LacB subunit (EC 5.3.1.26)
  • ⊞PFAM:
    no clan defined LacAB_rpiB; Ribose/Galactose Isomerase (PF02502; HMM-score: 141.4)
    and 4 more
    Gly_rich_SFCGS; Glycine-rich SFCGS (PF14272; HMM-score: 19.6)
    UPF0180; Uncharacterised protein family (UPF0180) (PF03698; HMM-score: 14.5)
    Acyl-CoA_desat (CL0713) FA_hydroxylase; Fatty acid hydroxylase (PF04116; HMM-score: 13.7)
    GT-B (CL0113) LpxB; Lipid-A-disaccharide synthetase (PF02684; HMM-score: 11.7)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • ⊞PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • ⊞SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.060714
    • TAT(Tat/SPI): 0.001049
    • LIPO(Sec/SPII): 0.003732
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: ADM84807 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MRIAIGCDHIVTDEKMAVSEFLKSKGYEVIDFGTYDHTRTHYPIFGKKVGEAVTSGQADLGVCICGTGVGINNAVNKVPGVRSALVRDMTTALYAKEQLNANVIGFGGKITGELLMCDIIEAFIHAEYKPSEENKKLIAKIEHHESHNAQQTDANFFTEFLEKWDRGEYHD

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

⊟Expression data[edit | edit source]

⊞Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊞Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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