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JJA
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MDRSPN001
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SPN994038
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TCH8431/19A
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serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 30-JAN-2014

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae CGSP14
  • locus tag: SPCG_1944 [new locus tag: SPCG_RS10195 ]
  • pan locus tag?: PNEUPAN003572000
  • symbol: SPCG_1944
  • pan gene symbol?: rmuC
  • synonym:
  • product: competence-induced protein Ccs50

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPCG_1944 [new locus tag: SPCG_RS10195 ]
  • symbol: SPCG_1944
  • product: competence-induced protein Ccs50
  • replicon: chromosome
  • strand: -
  • coordinates: 1928560..1929858
  • length: 1299
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    ATGGTTATGTGGTCGTACTGCATAGCAAGGATAGGAGGTAGGATGGAAAGTTTACTTATT
    CTATTATTAATTGCCAACCTAGCTGGTCTCTTTCTGATTTGGCAAAGGCAGGATAGGCAG
    GAGAAACACTTAAGTAAGAGCTTGGAGGATCAGGCAGATCATTTGTCAGACCAGTTGGAT
    TACCGCTTTGACCAAGCCAGACAAGCCAGCCAGTTAGACCAAAAAGATTTGGAAGTGGCT
    GTCAGCGACCGTTTGCAAGAAGTGCGGATTGAATTGCACCAAGGCCTGACCCAAGTCCGT
    CAAGAAATGACAGATAATCTCCTCCAAACTAGAGATAAGACAGACCATCGTCTCCAAGCC
    TTGCAGGAATCAAATGAGCAACGTTTGGAACAAATGCGCCAGACGGTCGAGGAAAAACTA
    GAAAAGACCTTGCAGACACGCTTACAGGCTTCCTTTGAGACAGTTTCTAAACAACTGGAG
    TCTGTCAATCGTGGTCTTGGAGAAATGCAGACAGTTGCCCGTGATGTCGGAGCTCTTAAC
    AAGGTTCTCTCTGGAACCAAGACGCGAGGGATTCTGGGAGAATTGCAACTGGGGCAAATT
    ATTGAAGACATCATGACACCTGCCCAGTACGAACGAGAATACGCAACGGTTGAAAACTCT
    AGTGAACGAGTGGAGTATGCCATCAAGTTACCCGGACAAGGCGACCAAGAATACGTCTAT
    CTTCCAATTGACTCTAAGTTTCCACTGGCAGATTATTACCGCTTGGAAGAAGCCTATGAG
    ACAGGTGACAAGGATGAGATTGAACGCTGTCGTAAGTCACTCCTAGCAAGCGTCAAGCGC
    TTTGCCAAGGATATCAAGAGCAAGTACATAGCACCGCCTCGGACAACCAACTTTGGAATC
    TTGTTTGTTCCGACAGAAGGTCTTTATTCAGAGATTGTGCGCAATCCGGTCTTCTTTGAT
    GATTTGAGACGGGAAGAACAGATTATTGTTGCAGGACCAAGTACCCTATCAGCCCTTCTT
    AACTCCCTATCAGTTGGTTTCAAGACCCTTAATATCCAAAAGAGTGCCGACCATATCAGC
    AAGACTCTTGCCAGTGTCAAGACCGAGTTTGGCAAGTTTGGTGGTATTCTGGTCAAGGCA
    CAAAAACATCTCCAACATGCCTCTGGCAATATTGATGAATTATTAAACCGTCGTACCATA
    GCTATCGAGCGGACGCTCCGTCACATTGAGTTGTCAGAAGGTGAGCCTGCGCTTGATCTA
    CTCTATTTTCAAGAAAATGAGGAAGAATATGAAGATTAG
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1299

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPCG_1944 [new locus tag: SPCG_RS10195 ]
  • symbol: SPCG_1944
  • description: competence-induced protein Ccs50
  • length: 432
  • theoretical pI: 4.97512
  • theoretical MW: 49538.7
  • GRAVY: -0.515972

⊟Function[edit | edit source]

  • ⊞TIGRFAM:
    Metabolism Fatty acid and phospholipid metabolism Biosynthesis poly(hydroxyalkanoate) granule-associated protein (TIGR01837; HMM-score: 11.1)
    and 2 more
    Cellular processes Cellular processes Sporulation and germination sporulation integral membrane protein YtvI (TIGR02872; HMM-score: 7.6)
    Genetic information processing DNA metabolism Degradation of DNA exodeoxyribonuclease VII, large subunit (TIGR00237; EC 3.1.11.6; HMM-score: 3.4)
  • TheSEED  :
    • DNA recombination protein RmuC
    DNA Metabolism DNA repair DNA repair, bacterial  DNA recombination protein RmuC
  • ⊞PFAM:
    PDDEXK (CL0236) RmuC; RmuC family (PF02646; HMM-score: 240.3)
    and 10 more
    no clan defined Apolipoprotein; Apolipoprotein A1/A4/E domain (PF01442; HMM-score: 21.2)
    Baculo_PEP_C; Baculovirus polyhedron envelope protein, PEP, C terminus (PF04513; HMM-score: 15.2)
    HTH (CL0123) DUF2089; Protein of unknown function (DUF2089) (PF09862; HMM-score: 11.4)
    no clan defined Exonuc_VII_L; Exonuclease VII, large subunit (PF02601; HMM-score: 9.6)
    HSCB_C; HSCB C-terminal oligomerisation domain (PF07743; HMM-score: 8.7)
    DUF4446; Protein of unknown function (DUF4446) (PF14584; HMM-score: 8.2)
    GT-B (CL0113) FUT8_N_cat; Alpha-(1,6)-fucosyltransferase N- and catalytic domains (PF19745; HMM-score: 8)
    no clan defined DUF948; Bacterial protein of unknown function (DUF948) (PF06103; HMM-score: 7.3)
    DUF1690; Protein of Unknown function (DUF1690) (PF07956; HMM-score: 6.9)
    Phasin; Poly(hydroxyalcanoate) granule associated protein (phasin) (PF05597; HMM-score: 6.8)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • ⊞PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 1.78
    • Cytoplasmic Membrane Score: 8.16
    • Cellwall Score: 0.06
    • Extracellular Score: 0.01
    • Internal Helix: 1
  • ⊞SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.033549
    • TAT(Tat/SPI): 0.002497
    • LIPO(Sec/SPII): 0.02921
  • predicted transmembrane helices (TMHMM): 1

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MVMWSYCIARIGGRMESLLILLLIANLAGLFLIWQRQDRQEKHLSKSLEDQADHLSDQLDYRFDQARQASQLDQKDLEVAVSDRLQEVRIELHQGLTQVRQEMTDNLLQTRDKTDHRLQALQESNEQRLEQMRQTVEEKLEKTLQTRLQASFETVSKQLESVNRGLGEMQTVARDVGALNKVLSGTKTRGILGELQLGQIIEDIMTPAQYEREYATVENSSERVEYAIKLPGQGDQEYVYLPIDSKFPLADYYRLEEAYETGDKDEIERCRKSLLASVKRFAKDIKSKYIAPPRTTNFGILFVPTEGLYSEIVRNPVFFDDLRREEQIIVAGPSTLSALLNSLSVGFKTLNIQKSADHISKTLASVKTEFGKFGGILVKAQKHLQHASGNIDELLNRRTIAIERTLRHIELSEGEPALDLLYFQENEEEYED

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

⊟Expression data[edit | edit source]

⊞Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊞Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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