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From PneumoWiki
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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 26-AUG-2017

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae OXC141
  • locus tag: SPNOXC13370 [new locus tag: SPNOXC_RS07210 ]
  • pan locus tag?: PNEUPAN002851000
  • symbol: SPNOXC13370
  • pan gene symbol?: metB
  • synonym:
  • product: putative cystathionine beta-lyase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPNOXC13370 [new locus tag: SPNOXC_RS07210 ]
  • symbol: SPNOXC13370
  • product: putative cystathionine beta-lyase
  • replicon: chromosome
  • strand: -
  • coordinates: 1357889..1358983
  • length: 1095
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    ATGAGCAAGGAATTACACATTAACACAATTTTGGCCCAGGCGGGTATTAAGTCAGATGAA
    GCGACAGGTGCATTGGTGACACCGCTTCATTTTTCAACGACCTATCAGCATCCAGAGTTT
    GGTCGATCTACTGGGTTTGACTATACGCGCACTAAAAATCCAACTCGTAGTAAGGCTGAG
    GAAGTCTTGGCGGCTATTGAGTCAGCAGACTATGCCTTAGCGACTAGCTCAGGGATGTCA
    GCTATTGTACTGGCCTTTAGCGTCTTTCCAGTAGGAAGTAAGGTCTTGGCAGTGCGTGAT
    CTTTACGGTGGTTCTTTTCGCTGGTTTAACCAAGTGGAGCAGGAAGGTCGTTTCCATTTT
    ACCTATGCCAATACAGAAGAAGAGTTGATTGCCGAGTTAGAAAAGGATGTGGATGTTCTC
    TATATCGAAACCCCAACCAATCCCTTGATGTTGGAATTTGATATCGAAAAACTAGCAAAA
    TTGGCTCATGCTAAGGGTGCCAAAGTGGTGGTGGACAATACCTTCTATAGCCCTATCTAC
    CAACGTCCGATTGAAGATAGAGCAGATATCGTTCTCCATTCAGCAACCAAGTATCTAGCA
    GGCCACAATGATGTCTTGGCTGGAGTGGTTGTGACCAATAGTTTAGAACTATACGAGAAG
    CTTTTTTACAATCTCAATACAACAGGGGCAGTCTTGTCTCCATTTGACAGCTACCAGTTG
    CTTCGTGGTCTCAAGACCTTGTCTCTTCGTATGGAGCGCTCAACAGCTAACGCCCAAGAA
    GTGGTTGCCTTTTTGAAGGATTCTCCAGCAGTTAAGGAAGTTCTCTACACTGGTCGTGGA
    GGCATGATTTCCTTTAAAGTAGCCGATGAAACACGCATTCCTCATATTTTGAACAGTCTC
    AAGGTCTTCTCTTTTGCGGAAAGTTTGGGCGGAGTGGAAAGTCTTATTACTTATCCAACG
    ACTCAAACTCATGCTGATATTCCAGCAGAAGTACGCCATTCTTATGGTTTGACAGATGAC
    CTCTTGCGTTTGTCTATTGGGATTGAGGATGCTAGAGATTTGATTGCAGATTTGCGCCAA
    GCCTTAGAAGGATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1095

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPNOXC13370 [new locus tag: SPNOXC_RS07210 ]
  • symbol: SPNOXC13370
  • description: putative cystathionine beta-lyase
  • length: 364
  • theoretical pI: 5.03319
  • theoretical MW: 40221.3
  • GRAVY: -0.0793956

⊟Function[edit | edit source]

  • ⊞⊞TIGRFAM:
    Metabolism Amino acid biosynthesis Aspartate family O-succinylhomoserine (thiol)-lyase (TIGR02080; EC 2.5.1.48; HMM-score: 360.5)
    cystathionine beta-lyase (TIGR01329; EC 4.4.1.8; HMM-score: 304.7)
    Metabolism Energy metabolism Amino acids and amines methionine gamma-lyase (TIGR01328; EC 4.4.1.11; HMM-score: 294.7)
    and 9 more
    Metabolism Amino acid biosynthesis Aspartate family O-succinylhomoserine sulfhydrylase (TIGR01325; EC 4.2.99.-; HMM-score: 266.2)
    Metabolism Amino acid biosynthesis Aspartate family O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase (TIGR01326; HMM-score: 237.7)
    Metabolism Amino acid biosynthesis Serine family O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase (TIGR01326; HMM-score: 237.7)
    Metabolism Amino acid biosynthesis Aspartate family cystathionine beta-lyase (TIGR01324; EC 4.4.1.8; HMM-score: 156.9)
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Heme, porphyrin, and cobalamin threonine-phosphate decarboxylase (TIGR01140; EC 4.1.1.81; HMM-score: 20.2)
    Unknown function Enzymes of unknown specificity cysteine desulfurase family protein (TIGR01976; HMM-score: 16.4)
    beta-methylarginine biosynthesis bifunctional aminotransferase (TIGR04544; EC 2.6.-.-; HMM-score: 16.1)
    2-aminoethylphosphonate aminotransferase (TIGR03301; EC 2.6.1.-; HMM-score: 13.7)
    Metabolism Amino acid biosynthesis Histidine family histidinol-phosphate transaminase (TIGR01141; EC 2.6.1.9; HMM-score: 12.4)
  • TheSEED  :
    • Cystathionine gamma-synthase (EC 2.5.1.48)
    Amino Acids and Derivatives Lysine, threonine, methionine, and cysteine Methionine Biosynthesis  Cystathionine gamma-synthase (EC 2.5.1.48)
  • ⊞⊞PFAM:
    PLP_aminotran (CL0061) Cys_Met_Meta_PP; Cys/Met metabolism PLP-dependent enzyme (PF01053; HMM-score: 390)
    and 5 more
    Aminotran_1_2; Aminotransferase class I and II (PF00155; HMM-score: 17.1)
    DegT_DnrJ_EryC1; DegT/DnrJ/EryC1/StrS aminotransferase family (PF01041; HMM-score: 16)
    Aminotran_5; Aminotransferase class-V (PF00266; HMM-score: 14)
    Alliinase_C; Allinase (PF04864; HMM-score: 12.5)
    Enolase_TIM (CL0256) MR_MLE_C; Enolase C-terminal domain-like (PF13378; HMM-score: 11.5)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • ⊞⊞PSORTb: Cytoplasmic
    • Cytoplasmic Score: 9.97
    • Cytoplasmic Membrane Score: 0
    • Cellwall Score: 0.01
    • Extracellular Score: 0.02
    • Internal Helices: 0
  • ⊞⊞SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.013988
    • TAT(Tat/SPI): 0.001737
    • LIPO(Sec/SPII): 0.002468
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: CBW32990 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MSKELHINTILAQAGIKSDEATGALVTPLHFSTTYQHPEFGRSTGFDYTRTKNPTRSKAEEVLAAIESADYALATSSGMSAIVLAFSVFPVGSKVLAVRDLYGGSFRWFNQVEQEGRFHFTYANTEEELIAELEKDVDVLYIETPTNPLMLEFDIEKLAKLAHAKGAKVVVDNTFYSPIYQRPIEDRADIVLHSATKYLAGHNDVLAGVVVTNSLELYEKLFYNLNTTGAVLSPFDSYQLLRGLKTLSLRMERSTANAQEVVAFLKDSPAVKEVLYTGRGGMISFKVADETRIPHILNSLKVFSFAESLGGVESLITYPTTQTHADIPAEVRHSYGLTDDLLRLSIGIEDARDLIADLRQALEG

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

⊟Expression data[edit | edit source]

⊞Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊞Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

Retrieved from "http://pneumowiki.med.uni-greifswald.de/index.php?title=SPNOXC13370&oldid=121485"
Insert paragraph

NCBI: 26-AUG-2017

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae OXC141
  • locus tag: SPNOXC13370 [new locus tag: SPNOXC_RS07210 ]
  • pan locus tag?: PNEUPAN002851000
  • symbol: SPNOXC13370
  • pan gene symbol?: metB
  • synonym:
  • product: putative cystathionine beta-lyase

Insert paragraph

⊟Genome View[edit | edit source]

Insert paragraph

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPNOXC13370 [new locus tag: SPNOXC_RS07210 ]
  • symbol: SPNOXC13370
  • product: putative cystathionine beta-lyase
  • replicon: chromosome
  • strand: -
  • coordinates: 1357889..1358983
  • length: 1095
  • essential: unknown

Insert paragraph

⊟Accession numbers[edit | edit source]

Insert paragraph

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    ATGAGCAAGGAATTACACATTAACACAATTTTGGCCCAGGCGGGTATTAAGTCAGATGAA
    GCGACAGGTGCATTGGTGACACCGCTTCATTTTTCAACGACCTATCAGCATCCAGAGTTT
    GGTCGATCTACTGGGTTTGACTATACGCGCACTAAAAATCCAACTCGTAGTAAGGCTGAG
    GAAGTCTTGGCGGCTATTGAGTCAGCAGACTATGCCTTAGCGACTAGCTCAGGGATGTCA
    GCTATTGTACTGGCCTTTAGCGTCTTTCCAGTAGGAAGTAAGGTCTTGGCAGTGCGTGAT
    CTTTACGGTGGTTCTTTTCGCTGGTTTAACCAAGTGGAGCAGGAAGGTCGTTTCCATTTT
    ACCTATGCCAATACAGAAGAAGAGTTGATTGCCGAGTTAGAAAAGGATGTGGATGTTCTC
    TATATCGAAACCCCAACCAATCCCTTGATGTTGGAATTTGATATCGAAAAACTAGCAAAA
    TTGGCTCATGCTAAGGGTGCCAAAGTGGTGGTGGACAATACCTTCTATAGCCCTATCTAC
    CAACGTCCGATTGAAGATAGAGCAGATATCGTTCTCCATTCAGCAACCAAGTATCTAGCA
    GGCCACAATGATGTCTTGGCTGGAGTGGTTGTGACCAATAGTTTAGAACTATACGAGAAG
    CTTTTTTACAATCTCAATACAACAGGGGCAGTCTTGTCTCCATTTGACAGCTACCAGTTG
    CTTCGTGGTCTCAAGACCTTGTCTCTTCGTATGGAGCGCTCAACAGCTAACGCCCAAGAA
    GTGGTTGCCTTTTTGAAGGATTCTCCAGCAGTTAAGGAAGTTCTCTACACTGGTCGTGGA
    GGCATGATTTCCTTTAAAGTAGCCGATGAAACACGCATTCCTCATATTTTGAACAGTCTC
    AAGGTCTTCTCTTTTGCGGAAAGTTTGGGCGGAGTGGAAAGTCTTATTACTTATCCAACG
    ACTCAAACTCATGCTGATATTCCAGCAGAAGTACGCCATTCTTATGGTTTGACAGATGAC
    CTCTTGCGTTTGTCTATTGGGATTGAGGATGCTAGAGATTTGATTGCAGATTTGCGCCAA
    GCCTTAGAAGGATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1095

Insert paragraph

This data comes from external databases and cannot be edited.

Insert paragraph

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPNOXC13370 [new locus tag: SPNOXC_RS07210 ]
  • symbol: SPNOXC13370
  • description: putative cystathionine beta-lyase
  • length: 364
  • theoretical pI: 5.03319
  • theoretical MW: 40221.3
  • GRAVY: -0.0793956

Insert paragraph

⊟Function[edit | edit source]

  • ⊞TIGRFAM:
    Metabolism Amino acid biosynthesis Aspartate family O-succinylhomoserine (thiol)-lyase (TIGR02080; EC 2.5.1.48; HMM-score: 360.5)
    cystathionine beta-lyase (TIGR01329; EC 4.4.1.8; HMM-score: 304.7)
    Metabolism Energy metabolism Amino acids and amines methionine gamma-lyase (TIGR01328; EC 4.4.1.11; HMM-score: 294.7)
    and 9 more
    Metabolism Amino acid biosynthesis Aspartate family O-succinylhomoserine sulfhydrylase (TIGR01325; EC 4.2.99.-; HMM-score: 266.2)
    Metabolism Amino acid biosynthesis Aspartate family O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase (TIGR01326; HMM-score: 237.7)
    Metabolism Amino acid biosynthesis Serine family O-acetylhomoserine aminocarboxypropyltransferase/cysteine synthase (TIGR01326; HMM-score: 237.7)
    Metabolism Amino acid biosynthesis Aspartate family cystathionine beta-lyase (TIGR01324; EC 4.4.1.8; HMM-score: 156.9)
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Heme, porphyrin, and cobalamin threonine-phosphate decarboxylase (TIGR01140; EC 4.1.1.81; HMM-score: 20.2)
    Unknown function Enzymes of unknown specificity cysteine desulfurase family protein (TIGR01976; HMM-score: 16.4)
    beta-methylarginine biosynthesis bifunctional aminotransferase (TIGR04544; EC 2.6.-.-; HMM-score: 16.1)
    2-aminoethylphosphonate aminotransferase (TIGR03301; EC 2.6.1.-; HMM-score: 13.7)
    Metabolism Amino acid biosynthesis Histidine family histidinol-phosphate transaminase (TIGR01141; EC 2.6.1.9; HMM-score: 12.4)
  • TheSEED  :
    • Cystathionine gamma-synthase (EC 2.5.1.48)
    Amino Acids and Derivatives Lysine, threonine, methionine, and cysteine Methionine Biosynthesis  Cystathionine gamma-synthase (EC 2.5.1.48)
  • ⊞PFAM:
    PLP_aminotran (CL0061) Cys_Met_Meta_PP; Cys/Met metabolism PLP-dependent enzyme (PF01053; HMM-score: 390)
    and 5 more
    Aminotran_1_2; Aminotransferase class I and II (PF00155; HMM-score: 17.1)
    DegT_DnrJ_EryC1; DegT/DnrJ/EryC1/StrS aminotransferase family (PF01041; HMM-score: 16)
    Aminotran_5; Aminotransferase class-V (PF00266; HMM-score: 14)
    Alliinase_C; Allinase (PF04864; HMM-score: 12.5)
    Enolase_TIM (CL0256) MR_MLE_C; Enolase C-terminal domain-like (PF13378; HMM-score: 11.5)

Insert paragraph

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Insert paragraph

⊟Localization[edit | edit source]

  • ⊞PSORTb: Cytoplasmic
    • Cytoplasmic Score: 9.97
    • Cytoplasmic Membrane Score: 0
    • Cellwall Score: 0.01
    • Extracellular Score: 0.02
    • Internal Helices: 0
  • ⊞SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.013988
    • TAT(Tat/SPI): 0.001737
    • LIPO(Sec/SPII): 0.002468
  • predicted transmembrane helices (TMHMM): 0

Insert paragraph

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: CBW32990 NCBI
  • UniProt:

Insert paragraph

⊟Protein sequence[edit | edit source]

  • MSKELHINTILAQAGIKSDEATGALVTPLHFSTTYQHPEFGRSTGFDYTRTKNPTRSKAEEVLAAIESADYALATSSGMSAIVLAFSVFPVGSKVLAVRDLYGGSFRWFNQVEQEGRFHFTYANTEEELIAELEKDVDVLYIETPTNPLMLEFDIEKLAKLAHAKGAKVVVDNTFYSPIYQRPIEDRADIVLHSATKYLAGHNDVLAGVVVTNSLELYEKLFYNLNTTGAVLSPFDSYQLLRGLKTLSLRMERSTANAQEVVAFLKDSPAVKEVLYTGRGGMISFKVADETRIPHILNSLKVFSFAESLGGVESLITYPTTQTHADIPAEVRHSYGLTDDLLRLSIGIEDARDLIADLRQALEG

Insert paragraph

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

Insert paragraph

⊟Expression & Regulation[edit | edit source]

Insert paragraph

⊟Operon[edit | edit source]

Insert paragraph

⊟Regulation[edit | edit source]

Insert paragraph

⊟Expression data[edit | edit source]

Insert paragraph

⊞Biological Material[edit | edit source]

This data comes from external databases and cannot be edited.

This data comes from external databases and cannot be edited.

This data comes from external databases and cannot be edited.

This data comes from external databases and cannot be edited.

This data comes from external databases and cannot be edited.

This data comes from external databases and cannot be edited.

This data comes from external databases and cannot be edited.

⊞Other Information[edit | edit source]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

Insert paragraph

⊟Relevant publications[edit | edit source]

Insert paragraph