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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 30-JAN-2014

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae R6
  • locus tag: spr0469 [new locus tag: SPR_RS11170 ]
  • pan locus tag?: PNEUPAN001401000
  • symbol: spr0469
  • pan gene symbol?: blpA2
  • synonym:
  • product: Conserved hypothetical protein, truncation

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: spr0469 [new locus tag: SPR_RS11170 ]
  • symbol: spr0469
  • product: Conserved hypothetical protein, truncation
  • replicon: chromosome
  • strand: -
  • coordinates: 475049..475642
  • length: 594
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: AE007317 (475049..475642) NCBI
  • BioCyc:
  • MicrobesOnline: 133354 MicrobesOnline
  • PneumoBrowse for strain D39V:

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    TTGCCAATGACTTCTTATAAACGTACATTTGTTCCTCAAATAGATGCGAGAGACTGTGGT
    GTCGCTGCCTTAGCCTCGATTGCTAAATTCTATGGTTCAGATTTTTCTCTAGCTCACTTG
    AGAGAACTTGCAAAGACCAATAAAGAAGGGACGACTGCTCTTGGCATTGTAAAAGCCGCT
    GATGAAATGGGCTTTGAAACAAGACCTGTTCAAGCATATAAAACGCTCTTTGACATGAGT
    GATGTCCCCTATCCATTTATCGTTCACGTTAACAAAGAAGGAAAATTCCAACATTACTAT
    GTTGTCTATCAAACAAAGAAAGACTATCTGATTATTGGTGATCCTGACCCTTCTGTAAAA
    ATCACTAAAATGTCAAAAGAACGCTTTTTCTATGAATGGACTGGAGTAGCTATTTTTCTA
    GCTACCAAACCCAGCTATCAACCCCATAAAGATAAAAAGAATGGTCTACTAAGCAAGCTT
    CCTTCCTCTGATTTTCAAACAAAAATCTCTCATTGCTTACATTGTTCTCTCAAGCTTATT
    GGTCACTATTATCAATATAGGTGGTTCTTACTATCTCCAAGGAATCTTGGATGA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    594

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: spr0469 [new locus tag: SPR_RS11170 ]
  • symbol: spr0469
  • description: Conserved hypothetical protein, truncation
  • length: 197
  • theoretical pI: 9.70725
  • theoretical MW: 22581
  • GRAVY: -0.324365

⊟Function[edit | edit source]

  • TIGRFAM:
    Genetic information processing Protein fate Protein and peptide secretion and trafficking ABC-type bacteriocin transporter (TIGR01193; HMM-score: 200.8)
    Genetic information processing Protein fate Protein modification and repair ABC-type bacteriocin transporter (TIGR01193; HMM-score: 200.8)
    Metabolism Transport and binding proteins Other ABC-type bacteriocin transporter (TIGR01193; HMM-score: 200.8)
    and 5 more
    Cellular processes Cellular processes Biosynthesis of natural products NHLM bacteriocin system ABC transporter, peptidase/ATP-binding protein (TIGR03796; HMM-score: 70.4)
    Metabolism Transport and binding proteins Amino acids, peptides and amines NHLM bacteriocin system ABC transporter, peptidase/ATP-binding protein (TIGR03796; HMM-score: 70.4)
    Genetic information processing Protein fate Protein and peptide secretion and trafficking type I secretion system ATPase (TIGR01846; HMM-score: 22)
    Cellular processes Cellular processes Pathogenesis type I secretion system ATPase (TIGR03375; HMM-score: 11.3)
    Genetic information processing Protein fate Protein and peptide secretion and trafficking type I secretion system ATPase (TIGR03375; HMM-score: 11.3)
  • TheSEED  :
    • Bacteriocin/lantibiotic efflux ABC transporter, permease/ATP-binding protein
    • Microcin maturation peptidase
    DNA Metabolism DNA uptake, competence Competence in Streptococci  Competence-stimulating peptide ABC transporter ATP-binding protein ComA
  • PFAM:
    Peptidase_CA (CL0125) Peptidase_C39; Peptidase C39 family (PF03412; HMM-score: 137.7)
    and 2 more
    Peptidase_C70; Papain-like cysteine protease AvrRpt2 (PF12385; HMM-score: 21.4)
    Peptidase_C39_2; Peptidase_C39 like family (PF13529; HMM-score: 18)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0.01
    • Cytoplasmic Membrane Score: 9.99
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic Membrane
    • Cytoplasmic Score: 0.1971
    • Cytoplasmic Membrane Score: 0.621
    • Cell wall & surface Score: 0.0007
    • Extracellular Score: 0.1813
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.00739
    • TAT(Tat/SPI): 0.002911
    • LIPO(Sec/SPII): 0.001338
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MPMTSYKRTFVPQIDARDCGVAALASIAKFYGSDFSLAHLRELAKTNKEGTTALGIVKAADEMGFETRPVQAYKTLFDMSDVPYPFIVHVNKEGKFQHYYVVYQTKKDYLIIGDPDPSVKITKMSKERFFYEWTGVAIFLATKPSYQPHKDKKNGLLSKLPSSDFQTKISHCLHCSLKLIGHYYQYRWFLLSPRNLG

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription[edit | edit source]

  • transcription start site:

⊟Expression data[edit | edit source]

  • PneumoExpress for strain D39V:

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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