From PneumoWiki
Jump to navigation Jump to search
PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 30-JAN-2014

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae R6
  • locus tag: spr1699 [new locus tag: SPR_RS08450 ]
  • pan locus tag?: PNEUPAN003377000
  • symbol: treP
  • pan gene symbol?: treP
  • synonym:
  • product: Phosphotransferase system, trehalose-specific IIBC component

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: spr1699 [new locus tag: SPR_RS08450 ]
  • symbol: treP
  • product: Phosphotransferase system, trehalose-specific IIBC component
  • replicon: chromosome
  • strand: -
  • coordinates: 1668093..1670210
  • length: 2118
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    1861
    1921
    1981
    2041
    2101
    ATGAACACCTGTATCTATTTTACCATACAAGTGCTAGAAAATTTACAAAAAAACACCCTT
    TTTATACCAAACAAGTTGCAGACAAGTTTGGTATCGTTTACAATATACTTATCAAATCAA
    ACTTGCTTTGACAAGTATAAGGAGAATCAAATGGGAAAATTTGAACAAGAAGCCAAAGAT
    TTGCTTCAGGCAATTGGAGGTAAAGAGAATGTGACTGCCGTCACCCACTGTGCGACACGG
    ATGCGGTTTGTTTTAGGAGATGATAAGAAGGCTAATGTTAAAGCTATCGAGTCAATTCCA
    GCTGTTAAAGGAACCTTTACAAATGCAGGTCAATTTCAGGTAATCATTGGAAATGACGTG
    CCCATCTTTTATAATGATTTTACAGCCGTTTCAGGTATTGAGGGTGTTTCCAAAGAAGCA
    GCCAAGTCTGCAGCTAAGAGTAATCAAAACGTGGTCCAAGGTGTTATGACCACTCTGGCG
    GAAATCTTTACTCCGATTATTCCAGCCTTGATTGTTGGTGGATTGATCCTCGGTTTCCGT
    AATGTCTTGGAAGGTGTCCATTGGTCGATGTTGGATGGCAAGACCATCACAGAATCCTCT
    CAGTTTTGGGCAGGGGTTAATCACTTCCTCTGGTTGCCTGGTGAAGCTATCTTCCAGTTC
    TTACCAGTAGGGATTACTTGGTCTGTTTCTCGTAAGATGGGAACCAGCCAAATTTTGGGA
    ATTGTTCTCGGAATCTGTTTGGTATCGCCTCAGTTGCTCAATGCCTATGCGGTTGCTTCA
    ACGCCAGCAGCTGATATCGCAGCAAACTGGGTTTGGAATTTTGGTTATTTTACTGTTAAT
    CGTATTGGTTACCAAGCCCAAGTTATCCCAGCCTTGCTTGCAGGTTTGAGTCTGTCTTAT
    CTTGAAATTTTTTGGCGCAAACATATCCCAGAAGTCATTTCCATGATTTTTGTACCTTTT
    TTGTCATTGATTCCAGCCTTGATTTTGGCTCATACTGTCTTGGGGCCAATCGGTTGGACA
    ATTGGACAAGGACTTTCATCAGTTGTATTGGCAGGTTTAACGGGTCCAGTTAAATGGCTC
    TTCGGTGCAATTTTTGGTGCCCTCTACGCTCCATTTGTCATCACAGGTCTGCACCACATG
    ACCAATGCCATTGATACACAATTGATTGCGGATGCTGGTGGCACTGCCCTCTGGCCTATG
    ATTGCTCTTTCTAATATTGCTCAAGGCTCAGCCGTGTTTGCCTATTATTTCATGCATCGC
    CATGATGAGCGTGAGGCTCAGGTTTCACTTCCTGCAACCATTTCAGCCTATCTCGGTGTT
    ACAGAACCAGCTCTTTTTGGGGTTAACGTAAAATATATTTATCCATTTGTTGCTGGGATG
    ACTGGTTCAGCCCTTGCAGGCATGTTATCCGTTATTTTTAATGTAACTGCGGCTTCTATT
    GGTATCGGTGGTTTGCCAGGTATTCTCTCTATTCAACCTCAATACATGCTGCCATTTGCA
    GGAACTATGCTAGTTGCGATTGTTGTTCCAATGCTCTTGACTTTCTTCTTCCGCAAGGCT
    GGTCTCTTTACAAAAACAGAGGGCGATACGAACTTGCAGGCAGAATTCGTTGCTCAAGAA
    GAAGCAGAATTTGTGAGCCATGAACTAGTAGAACTTACTTCGGTAGAAATTATCAGCCCA
    CTAACTGGCCAAGTGAAAGAATTGAGTCAAGCGACGGATCCTGTTTTTGCATCAGGTGTC
    ATGGGGCAAGGTCTGGTCATTGAACCAAGCCAAGGTGAGTTGACCTCTCCAGTTAATGGA
    ACAGTGACGGTTCTTTTCCCTACCAAGCATGCCATCGGCATTGTCTCTGACGAGGGAGTT
    GAATTGCTCATCCACATCGGTATGGATACAGTAGGTCTTGATGGCAAAGGTTTTGAAAGT
    CTTGTAGTCCAAGGAGATCACGTTACAGTTGGTCAGCAACTGATTCGTTTTGATATGGAT
    GTCATTAAGGCTGCAGGTCTGGTGACAGAAACTCCTGTTATCATCACCAACCAAGATGCT
    TATACAGCGACTATTACTGGAACTTATCCGACAACGATCCAAGCTGGAGCATCTCTCATG
    GTCGCTACACGAATCTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1380
    1440
    1500
    1560
    1620
    1680
    1740
    1800
    1860
    1920
    1980
    2040
    2100
    2118

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: spr1699 [new locus tag: SPR_RS08450 ]
  • symbol: TreP
  • description: Phosphotransferase system, trehalose-specific IIBC component
  • length: 705
  • theoretical pI: 5.16684
  • theoretical MW: 75716.4
  • GRAVY: 0.471348

⊟Function[edit | edit source]

  • reaction:
    EC 2.7.1.69?  ExPASy
    Transferred entry: 2.7.1.191, 2.7.1.192, 2.7.1.193, 2.7.1.194, 2.7.1.195, 2.7.1.196, 2.7.1.197, 2.7.1.198, 2.7.1.199, 2.7.1.200, 2.7.1.201, 2.7.1.202, 2.7.1.203, 2.7.1.204, 2.7.1.205, 2.7.1.206, 2.7.1.207 and 2.7.1.208
  • TIGRFAM:
    PTS system, trehalose-specific IIBC component (TIGR01992; EC 2.7.1.69; HMM-score: 723.7)
    and 12 more
    PTS system, beta-glucoside-specific IIABC component (TIGR01995; EC 2.7.1.69; HMM-score: 485.9)
    PTS system, sucrose-specific IIBC component (TIGR01996; EC 2.7.1.69; HMM-score: 433.6)
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids PTS system, maltose and glucose-specific subfamily, IIC component (TIGR00852; HMM-score: 215.4)
    Signal transduction Signal transduction PTS PTS system, maltose and glucose-specific subfamily, IIC component (TIGR00852; HMM-score: 215.4)
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids PTS system, glucose subfamily, IIA component (TIGR00830; HMM-score: 137.4)
    Signal transduction Signal transduction PTS PTS system, glucose subfamily, IIA component (TIGR00830; HMM-score: 137.4)
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids PTS system, glucose-like IIB component (TIGR00826; EC 2.7.1.69; HMM-score: 65.6)
    Signal transduction Signal transduction PTS PTS system, glucose-like IIB component (TIGR00826; EC 2.7.1.69; HMM-score: 65.6)
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids PTS system, maltose and glucose-specific IIBC component (TIGR02004; EC 2.7.1.69; HMM-score: 40)
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids PTS system, alpha-glucoside-specific IIBC component (TIGR02005; EC 2.7.1.69; HMM-score: 39.5)
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids PTS system, N-acetylglucosamine-specific IIBC component (TIGR01998; EC 2.7.1.69; HMM-score: 39)
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids PTS system, glucose-specific IIBC component (TIGR02002; EC 2.7.1.69; HMM-score: 23)
  • TheSEED  :
    • PTS system, trehalose-specific IIA component (EC 2.7.1.201)
    • PTS system, trehalose-specific IIB component (EC 2.7.1.201)
    • PTS system, trehalose-specific IIC component
    Carbohydrates Di- and oligosaccharides Trehalose Uptake and Utilization  PTS system, trehalose-specific IIA component (EC 2.7.1.69)
    and 2 more
    Carbohydrates Di- and oligosaccharides Trehalose Uptake and Utilization  PTS system, trehalose-specific IIB component (EC 2.7.1.69)
    Carbohydrates Di- and oligosaccharides Trehalose Uptake and Utilization  PTS system, trehalose-specific IIC component (EC 2.7.1.69)
  • PFAM:
    Hybrid (CL0105) PTS_EIIA_1; phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 1 (PF00358; HMM-score: 162.4)
    and 3 more
    PTS_EIIC (CL0493) PTS_EIIC; Phosphotransferase system, EIIC (PF02378; HMM-score: 127.6)
    no clan defined PTS_EIIB; phosphotransferase system, EIIB (PF00367; HMM-score: 51.9)
    Hybrid (CL0105) RnfC_N; RnfC Barrel sandwich hybrid domain (PF13375; HMM-score: 12.1)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 10
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.033395
    • TAT(Tat/SPI): 0.000184
    • LIPO(Sec/SPII): 0.002639
  • predicted transmembrane helices (TMHMM): 10

⊟Accession numbers[edit | edit source]

⊟Protein sequence[edit | edit source]

  • MNTCIYFTIQVLENLQKNTLFIPNKLQTSLVSFTIYLSNQTCFDKYKENQMGKFEQEAKDLLQAIGGKENVTAVTHCATRMRFVLGDDKKANVKAIESIPAVKGTFTNAGQFQVIIGNDVPIFYNDFTAVSGIEGVSKEAAKSAAKSNQNVVQGVMTTLAEIFTPIIPALIVGGLILGFRNVLEGVHWSMLDGKTITESSQFWAGVNHFLWLPGEAIFQFLPVGITWSVSRKMGTSQILGIVLGICLVSPQLLNAYAVASTPAADIAANWVWNFGYFTVNRIGYQAQVIPALLAGLSLSYLEIFWRKHIPEVISMIFVPFLSLIPALILAHTVLGPIGWTIGQGLSSVVLAGLTGPVKWLFGAIFGALYAPFVITGLHHMTNAIDTQLIADAGGTALWPMIALSNIAQGSAVFAYYFMHRHDEREAQVSLPATISAYLGVTEPALFGVNVKYIYPFVAGMTGSALAGMLSVIFNVTAASIGIGGLPGILSIQPQYMLPFAGTMLVAIVVPMLLTFFFRKAGLFTKTEGDTNLQAEFVAQEEAEFVSHELVELTSVEIISPLTGQVKELSQATDPVFASGVMGQGLVIEPSQGELTSPVNGTVTVLFPTKHAIGIVSDEGVELLIHIGMDTVGLDGKGFESLVVQGDHVTVGQQLIRFDMDVIKAAGLVTETPVIITNQDAYTATITGTYPTTIQAGASLMVATRI

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

Retrieved from "http://pneumowiki.med.uni-greifswald.de/index.php?title=spr1699&oldid=130360"