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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 19-NOV-2015

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae A66
  • locus tag: A66_01154 [new locus tag: A66_RS05755 ]
  • pan locus tag?: PNEUPAN002517000
  • symbol: A66_01154
  • pan gene symbol?: —
  • synonym:
  • product: Glutamate synthase [NADPH] large chain

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: A66_01154 [new locus tag: A66_RS05755 ]
  • symbol: A66_01154
  • product: Glutamate synthase [NADPH] large chain
  • replicon: chromosome
  • strand: -
  • coordinates: 1121170..1122114
  • length: 945
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: LN847353 (1121170..1122114) NCBI
  • BioCyc:
  • MicrobesOnline:
  • PneumoBrowse for strain D39V: SPV_1121 PneumoBrowse

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    ATGCTTATCGCCTCTATCGGATTAAATATGGATTCGACTCCCGTGATTATTGGAGCCATG
    TTAATCTCTCCTTTGATGACACCTATTCTGGGAGTGGGGCTCTCTCTAGCTATATTTGAT
    TTTAAATTGTTAAGAAAATCTTTTAAAATATTAGCTATTCAAATTCTTGCCAGTTTAATA
    GCTTCAACACTTTATTTTTATCTTTCTCCCATTTCGTATGCTAGTTCGGAAATTGTTGCT
    AGAACCTCTCCGACTATTTGGGATGTTCTCATTGCTTTTGTAGGAGGGATAGCAGGTATT
    ATTGGTGCTAGAAAAAAAGAGACCAATAATATTGTTCCTGGTGTTGCTATTGCAACCGCC
    TTGATGCCTCCTCTTTGTACAGTAGGTTATGCTATTGCTTCTGCTAATCTAAAATTTATC
    ATAGGCTCCTCTTACCTATTCCTCATCAATTGTAGCTTTATTGTCATTGCGACTTATATA
    GGTGTTAGGTTGATGATGGTTAAGAAACATTATTTTAAAGATAATGAAGAAGACTCTAAA
    ATGCGTAGGATTTTGCTTCTAGTTGCTGTTTTGCTGATGATTCCGAGTTTCATCTCTGCA
    ACGACTTTAGTGAGAGAAACGTTGAAAAAAGAGTCCCTTAAGAAATTTATATCAGAGCAG
    TTTCAGGGGCATAATATTTTGAAAAAAACCTATTCTAAAAAGACTCATACCCTAAAGCTA
    ACCATTTCAGGAAATTATTTGACAGAAGAAGAACTCGATATGATTTCAAGTAAGAGAGGT
    GACTATGGTTTAAGTGATGTTTCTGTTCAAGTTTCACAATTGTCTGATTCAGAACAACTT
    AGTAAGGAAGAACTGGTGGAGTATTTCTTCCAGTATATCAAGGATAAAGAAACAAAAGAA
    AAGGAAAAAGCTAATAAGTTTTATACAGAGTCTGAGGAGCAATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    945

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: A66_01154 [new locus tag: A66_RS05755 ]
  • symbol: A66_01154
  • description: Glutamate synthase [NADPH] large chain
  • length: 314
  • theoretical pI: 9.27298
  • theoretical MW: 34990
  • GRAVY: 0.281529

⊟Function[edit | edit source]

  • reaction:
    EC 1.4.1.13?  ExPASy
    Glutamate synthase (NADPH) 2 L-glutamate + NADP+ = L-glutamine + 2-oxoglutarate + NADPH
  • TIGRFAM:
    uncharacterized hydrophobic domain (TIGR00271; HMM-score: 105.3)
    Hypothetical proteins Conserved TIGR00341 family protein (TIGR00341; HMM-score: 91.5)
  • TheSEED: data available for D39, Hungary19A-6, TIGR4
  • PFAM:
    no clan defined DUF389; Domain of unknown function (DUF389) (PF04087; HMM-score: 132.4)
    and 4 more
    DUF624; Protein of unknown function, DUF624 (PF04854; HMM-score: 14.9)
    SWIB; SWIB/MDM2 domain (PF02201; HMM-score: 13.7)
    Wzz; Chain length determinant protein (PF02706; HMM-score: 10.7)
    PHO4; Phosphate transporter family (PF01384; HMM-score: 10.1)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 6
  • DeepLocPro: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 0.9987
    • Cell wall & surface Score: 0
    • Extracellular Score: 0.0013
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.001429
    • TAT(Tat/SPI): 0.000107
    • LIPO(Sec/SPII): 0.007202
  • predicted transmembrane helices (TMHMM): 6

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: CRI61865 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MLIASIGLNMDSTPVIIGAMLISPLMTPILGVGLSLAIFDFKLLRKSFKILAIQILASLIASTLYFYLSPISYASSEIVARTSPTIWDVLIAFVGGIAGIIGARKKETNNIVPGVAIATALMPPLCTVGYAIASANLKFIIGSSYLFLINCSFIVIATYIGVRLMMVKKHYFKDNEEDSKMRRILLLVAVLLMIPSFISATTLVRETLKKESLKKFISEQFQGHNILKKTYSKKTHTLKLTISGNYLTEEELDMISSKRGDYGLSDVSVQVSQLSDSEQLSKEELVEYFFQYIKDKETKEKEKANKFYTESEEQ

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription[edit | edit source]

  • transcription start site:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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