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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 17-DEC-2024

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae A66
  • locus tag: A66_RS04005 [old locus tag: A66_00804 ]
  • pan locus tag?: PNEUPAN001845000
  • symbol: A66_RS04005
  • pan gene symbol?: rizA
  • synonym:
  • product: ATP-grasp domain-containing protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: A66_RS04005 [old locus tag: A66_00804 ]
  • symbol: A66_RS04005
  • product: ATP-grasp domain-containing protein
  • replicon: chromosome
  • strand: +
  • coordinates: 771329..772495
  • length: 1167
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: NZ_LN847353 (771329..772495) NCBI
  • BioCyc:
  • MicrobesOnline:
  • PneumoBrowse for strain D39V: SPV_0781 PneumoBrowse

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    ATGAATTACCTTGTTATTTCTCCCTACTATCCACAAAACTTTCAACAGTTTACCATCGAA
    CTAGCTAATAAAGGCATCACAGTCTTGGGAATTGGTCAAGAGTCTTACGAGCAATTGGAT
    GAGCCCTTGCGCAATAGCTTGACCGAGTATTTTCGTGTTGATAATCTTGAGAACATAGAT
    GAAGTCAAACGTGCAGTGGCTTTTCTCTTTTATAAACATGGTCCAATTAACCGCATCGAG
    TCTCACAATGAATACTGGCTTGAGCTAGACGCAACACTCAGAGAACAATTCAATGTTTTT
    GGTGCCAAACCAGAGGATCTCAAAAAGACGAAATATAAGTCTGAAATGAAGAAACTTTTC
    AAAAAAGCAGGTGTTCCTGTGGTACCTGGAGCTGTTATCAAGACGGAAGCAGATGTTGAT
    CAAGCAGTGAAAGAAATCGGTCTTCCAATGATTGCCAAACCTGATAATGGAGTGGGAGCA
    GCCGCAACCTTTAAACTTGAGACAGAAGACGATATCAATCACTTCAAGCAAGAATGGGAC
    CATTCAACCCTTTATTTCTTTGAAAAATTTGTCACTTCCAGCGAAATCTGTACCTTTGAC
    GGGCTCGTGGACAAGGATGGAAAGATTGTTTTCTCAACAACCTTTGACTACGCCTATACA
    CCGCTTGATCTCATGATTTATAAGATGGACAATTCCTACTATGTGCTCAAGGATATGGTT
    CCCAAACTACGCAAGTATGGGGAAGCTATTGTTAAGGAATTTGGTATGAAAGAACGTTTC
    TTCCATATCGAGTTTTTCCGTGAAGGGGATGATTATATCGCCATTGAGTACAATAACCGC
    CCTGCAGGTGGTTTCACCATTGATGTTTATAACTTTGCTCATTCCTTGGACCTCTATCGT
    GGATATGCAGCCATTGTCGCAGGAGAAGAGTTCCCAGCGTCAGAGTTTGAACCTCAGTAT
    TGTTTGGCTACATCACGTCGTGCAAATGCTCACTATGTCTATTCTGAGGAGAACTTACTT
    GTCAAATATAGCCAGCAGTTCAAGGTTAAAAAAATCATGCCAGAGGCTTTTGCGGAACTT
    CAAGGAGATTACTTTTATATGCTGACAACTCCGAGTCGACAAGAAATGGATCAGATGATT
    GCTGATTTCGGACAACGTCAAGAATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1167

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: A66_RS04005 [old locus tag: A66_00804 ]
  • symbol: A66_RS04005
  • description: ATP-grasp domain-containing protein
  • length: 388
  • theoretical pI: 4.73044
  • theoretical MW: 45049.7
  • GRAVY: -0.41933

⊟Function[edit | edit source]

  • reaction:
    EC 6.-.-.-?  ExPASy
  • TIGRFAM:
    Cellular processes Cellular processes Biosynthesis of natural products cyanophycin synthetase (TIGR02068; EC 6.3.2.29,6.3.2.30; HMM-score: 33.6)
    Metabolism Fatty acid and phospholipid metabolism Biosynthesis acetyl-CoA carboxylase, biotin carboxylase subunit (TIGR00514; EC 6.3.4.14; HMM-score: 30.7)
    and 8 more
    Metabolism Purines, pyrimidines, nucleosides, and nucleotides Pyrimidine ribonucleotide biosynthesis carbamoyl-phosphate synthase, large subunit (TIGR01369; EC 6.3.5.5; HMM-score: 24.6)
    Metabolism Energy metabolism Glycolysis/gluconeogenesis pyruvate carboxylase (TIGR01235; EC 6.4.1.1; HMM-score: 23.9)
    Metabolism Purines, pyrimidines, nucleosides, and nucleotides Purine ribonucleotide biosynthesis phosphoribosylaminoimidazole carboxylase, ATPase subunit (TIGR01161; EC 4.1.1.21; HMM-score: 23.4)
    Metabolism Central intermediary metabolism Nitrogen metabolism urea carboxylase (TIGR02712; EC 6.3.4.6; HMM-score: 22.5)
    alpha-L-glutamate ligase, RimK family (TIGR00768; EC 6.3.2.-; HMM-score: 20.1)
    Cell structure Cell envelope Biosynthesis and degradation of murein sacculus and peptidoglycan D-alanine--D-alanine ligase (TIGR01205; EC 6.3.2.4; HMM-score: 19.2)
    lysine biosynthesis enzyme LysX (TIGR02144; HMM-score: 14.5)
    Metabolism Energy metabolism TCA cycle succinate-CoA ligase, beta subunit (TIGR01016; EC 6.2.1.-; HMM-score: 11.3)
  • TheSEED: data available for D39, Hungary19A-6, TIGR4
  • PFAM:
    ATP-grasp (CL0179) ATP-grasp_4; ATP-grasp domain (PF13535; HMM-score: 30.1)
    and 5 more
    CPSase_L_D2; Carbamoyl-phosphate synthase L chain, ATP binding domain (PF02786; HMM-score: 22.7)
    no clan defined WG_beta_rep; WG containing repeat (PF14903; HMM-score: 18.2)
    ATP-grasp (CL0179) ATP-grasp; ATP-grasp domain (PF02222; HMM-score: 16.3)
    ATP-grasp_5; ATP-grasp domain (PF13549; HMM-score: 15)
    ATP-grasp_3; ATP-grasp domain (PF02655; HMM-score: 13.9)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: unknown (no significant prediction)
    • Cytoplasmic Score: 2.5
    • Cytoplasmic Membrane Score: 2.5
    • Cellwall Score: 2.5
    • Extracellular Score: 2.5
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.9861
    • Cytoplasmic Membrane Score: 0.0064
    • Cell wall & surface Score: 0.0001
    • Extracellular Score: 0.0075
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.003305
    • TAT(Tat/SPI): 0.000169
    • LIPO(Sec/SPII): 0.000534
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_001108652 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MNYLVISPYYPQNFQQFTIELANKGITVLGIGQESYEQLDEPLRNSLTEYFRVDNLENIDEVKRAVAFLFYKHGPINRIESHNEYWLELDATLREQFNVFGAKPEDLKKTKYKSEMKKLFKKAGVPVVPGAVIKTEADVDQAVKEIGLPMIAKPDNGVGAAATFKLETEDDINHFKQEWDHSTLYFFEKFVTSSEICTFDGLVDKDGKIVFSTTFDYAYTPLDLMIYKMDNSYYVLKDMVPKLRKYGEAIVKEFGMKERFFHIEFFREGDDYIAIEYNNRPAGGFTIDVYNFAHSLDLYRGYAAIVAGEEFPASEFEPQYCLATSRRANAHYVYSEENLLVKYSQQFKVKKIMPEAFAELQGDYFYMLTTPSRQEMDQMIADFGQRQE

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription[edit | edit source]

  • transcription start site:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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