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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 17-DEC-2024

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae A66
  • locus tag: A66_RS08865 [old locus tag: A66_01766 ]
  • pan locus tag?: PNEUPAN003588000
  • symbol: asnA
  • pan gene symbol?: asnA
  • synonym:
  • product: aspartate--ammonia ligase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: A66_RS08865 [old locus tag: A66_01766 ]
  • symbol: asnA
  • product: aspartate--ammonia ligase
  • replicon: chromosome
  • strand: -
  • coordinates: 1686446..1687438
  • length: 993
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: NZ_LN847353 (1686446..1687438) NCBI
  • BioCyc:
  • MicrobesOnline:
  • PneumoBrowse for strain D39V: SPV_1768 PneumoBrowse

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    ATGAAGAAAAGTTTTATCCATCAACAAGAAGAAATTTCCTTTGTCAAAAACACTTTTACC
    CAGTATTTGAAAGATAAGCTAGAAGTTGTCGAAGTTCAAGGTCCTATCTTGAGTAAGGTC
    GGTGACGGAATGCAGGACAACCTGTCTGGTGTGGAAAATCCAGTATCGGTCAAGGTTCTC
    CAAATCCCTGATGCTACTTATGAAGTGGTGCACTCACTTGCTAAATGGAAACGCCACACC
    TTGGCTCGTTTTGGCTTTGGTGAAGGAGAGGGTCTCTTTGTCCACATGAAAGCCCTTCGT
    CCAGATGAGGATTCCTTGGATGCAACCCACTCTGTTTATGTTGACCAGTGGGACTGGGAG
    AAGGTTATCCCAAATGGTAAGCGTAACATCGTTTATCTAAAAGAAACAGTTGAGAAGATT
    TATAAGGCTATTCGCCTGACTGAGCTAGCTGTTGAAGCTCGCTATGACATCGAGTCTATC
    TTGCCAAAACAAATCACCTTTATCCATACAGAAGAATTGGTAGAACGCTACCCAGACTTG
    ACACCGAAAGAACGTGAAAATGCGATTTGTAAAGAATTTGGAGCCGTCTTTTTGATTGGT
    ATCGGTGGCGAGTTGCCAGATGGTAAACCGCACGATGGACGTGCACCAGACTATGATGAC
    TGGACAAGCGAGTCTGAGAATGGCTACAAGGGTCTAAATGGTGATATTCTTGTCTGGAAT
    GAGTCTTTAGGTGGAGCCTTTGAGTTGTCTTCTATGGGAATTCGTGTAGATGAAGAAACT
    CTTAGACGTCAGGTGGAAATTACAGGTGATGAAGACCGCTTGGAATTGGAATGGCACAAG
    TCTTTGTTGAATGGCCTATTCCCATTGACAATCGGTGGAGGAATTGGACAATCTCGTATG
    GCCATGTTCCTACTTCGCAAGAGACACATCGGAGAAGTGCAAACAAGTGTTTGGCCTCAA
    GAAGTCCGCGATACTTACGAAAATATTTTGTAG
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    993

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: A66_RS08865 [old locus tag: A66_01766 ]
  • symbol: AsnA
  • description: aspartate--ammonia ligase
  • length: 330
  • theoretical pI: 4.80319
  • theoretical MW: 37617.4
  • GRAVY: -0.433333

⊟Function[edit | edit source]

  • reaction:
    EC 6.3.1.1?  ExPASy
    Aspartate--ammonia ligase ATP + L-aspartate + NH3 = AMP + diphosphate + L-asparagine
  • TIGRFAM:
    Metabolism Amino acid biosynthesis Aspartate family aspartate--ammonia ligase (TIGR00669; EC 6.3.1.1; HMM-score: 608.4)
  • TheSEED: data available for D39, Hungary19A-6, TIGR4
  • PFAM:
    tRNA_synt_II (CL0040) AsnA; Aspartate-ammonia ligase (PF03590; HMM-score: 321.8)
    and 1 more
    tRNA-synt_2; tRNA synthetases class II (D, K and N) (PF00152; HMM-score: 15.3)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 10
    • Cytoplasmic Membrane Score: 0
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.9978
    • Cytoplasmic Membrane Score: 0
    • Cell wall & surface Score: 0
    • Extracellular Score: 0.0022
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.005644
    • TAT(Tat/SPI): 0.000385
    • LIPO(Sec/SPII): 0.000488
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_000747993 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MKKSFIHQQEEISFVKNTFTQYLKDKLEVVEVQGPILSKVGDGMQDNLSGVENPVSVKVLQIPDATYEVVHSLAKWKRHTLARFGFGEGEGLFVHMKALRPDEDSLDATHSVYVDQWDWEKVIPNGKRNIVYLKETVEKIYKAIRLTELAVEARYDIESILPKQITFIHTEELVERYPDLTPKERENAICKEFGAVFLIGIGGELPDGKPHDGRAPDYDDWTSESENGYKGLNGDILVWNESLGGAFELSSMGIRVDEETLRRQVEITGDEDRLELEWHKSLLNGLFPLTIGGGIGQSRMAMFLLRKRHIGEVQTSVWPQEVRDTYENIL

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription[edit | edit source]

  • transcription start site:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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