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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 03-SEP-2019

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae ASP0581
  • locus tag: ASP0581_07690 [new locus tag: EL334_RS04100 ]
  • pan locus tag?: PNEUPAN001779000
  • symbol: ASP0581_07690
  • pan gene symbol?: flaR
  • synonym:
  • product: hypothetical protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: ASP0581_07690 [new locus tag: EL334_RS04100 ]
  • symbol: ASP0581_07690
  • product: hypothetical protein
  • replicon: chromosome
  • strand: +
  • coordinates: 768048..768422
  • length: 375
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: AP019192 (768048..768422) NCBI
  • BioCyc: see EL334_RS04100
  • MicrobesOnline:
  • PneumoBrowse for strain D39V:

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    TTGAAAGAGTCAGAAAATGATGCTCCAAAACTAGAAACTCCTCTTAGAGAGGAGCCAAGA
    CTAGCTCCTCAAACGCTTCCGGAAGCAAGTGAAGTTCTTGAAAACAAAAGGGAAGAGTCA
    AAAGTAGAGATAACAGAGCCAGCTCAAGCGGATGATATCCGCAAGGTTGTTGGGGAATTA
    GCCAAGGATATAAGTATTACTAAGTTGTATATGACAGGTCATTCTCTTGGAGGCTACCTA
    GCTCAGATTGCAGCGGTTGAAGATTACCAAAAATATCCTGATTTTTATAACCATGTATTG
    AGGAAAGTGACAACTTTCAGTGCTCCTAAAGTGATTACTTCCAGAACTGTTTGGGATGCT
    AAGAATGGTTTCTGA
    60
    120
    180
    240
    300
    360
    375

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: ASP0581_07690 [new locus tag: EL334_RS04100 ]
  • symbol: ASP0581_07690
  • description: hypothetical protein
  • length: 124
  • theoretical pI: 5.01276
  • theoretical MW: 13993.7
  • GRAVY: -0.621774

⊟Function[edit | edit source]

  • TIGRFAM:
    proline-specific peptidase (TIGR01250; HMM-score: 15.8)
    glutaredoxin (TIGR02180; HMM-score: 14.6)
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Menaquinone and ubiquinone 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase (TIGR03695; EC 4.2.99.20; HMM-score: 14.1)
    and 1 more
    Metabolism Energy metabolism Other 3-oxoadipate enol-lactonase (TIGR02427; EC 3.1.1.24; HMM-score: 11.4)
  • TheSEED: data available for Hungary19A-6
  • PFAM:
    AB_hydrolase (CL0028) Lipase_3; Lipase (class 3) (PF01764; HMM-score: 31.3)
    and 12 more
    Hydrolase_4; Serine aminopeptidase, S33 (PF12146; HMM-score: 18.4)
    Abhydrolase_6; Alpha/beta hydrolase family (PF12697; HMM-score: 16.8)
    DUF915; Alpha/beta hydrolase of unknown function (DUF915) (PF06028; HMM-score: 16.2)
    PGAP1; PGAP1-like protein (PF07819; HMM-score: 14.7)
    Peptidase_S9; Prolyl oligopeptidase family (PF00326; HMM-score: 14.5)
    Mbeg1-like; Mbeg1-like (PF11187; HMM-score: 14.4)
    Abhydrolase_3; alpha/beta hydrolase fold (PF07859; HMM-score: 13.9)
    LIDHydrolase; Lipid-droplet associated hydrolase (PF10230; HMM-score: 13.7)
    BD-FAE; BD-FAE (PF20434; HMM-score: 13.7)
    Abhydrolase_1; alpha/beta hydrolase fold (PF00561; HMM-score: 13.3)
    DUF676; Putative serine esterase (DUF676) (PF05057; HMM-score: 12.9)
    Esterase; Putative esterase (PF00756; HMM-score: 12.5)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: unknown (no significant prediction)
    • Cytoplasmic Score: 2.5
    • Cytoplasmic Membrane Score: 2.5
    • Cellwall Score: 2.5
    • Extracellular Score: 2.5
    • Internal Helices: 0
  • DeepLocPro: Extracellular
    • Cytoplasmic Score: 0.0008
    • Cytoplasmic Membrane Score: 0.0078
    • Cell wall & surface Score: 0.0008
    • Extracellular Score: 0.9906
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.016299
    • TAT(Tat/SPI): 0.001311
    • LIPO(Sec/SPII): 0.001753
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: BBG81291 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MKESENDAPKLETPLREEPRLAPQTLPEASEVLENKREESKVEITEPAQADDIRKVVGELAKDISITKLYMTGHSLGGYLAQIAAVEDYQKYPDFYNHVLRKVTTFSAPKVITSRTVWDAKNGF

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription[edit | edit source]

  • transcription start site:

⊟Expression data[edit | edit source]

  • PneumoExpress for strain D39V:

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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