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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 13-OCT-2024

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae NCTC7465
  • locus tag: AT689_RS11650
  • pan locus tag?: PNEUPAN003225000
  • symbol: AT689_RS11650
  • pan gene symbol?: psrP
  • synonym:
  • product: accessory Sec-dependent serine-rich glycoprotein adhesin

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: AT689_RS11650
  • symbol: AT689_RS11650
  • product: accessory Sec-dependent serine-rich glycoprotein adhesin
  • replicon: chromosome
  • strand: +
  • coordinates: 971597..976975
  • length: 5379
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: NZ_LN831051 (971597..976975) NCBI
  • BioCyc: AT689_RS11650 BioCyc
  • MicrobesOnline:
  • PneumoBrowse for strain D39V:

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    1861
    1921
    1981
    2041
    2101
    2161
    2221
    2281
    2341
    2401
    2461
    2521
    2581
    2641
    2701
    2761
    2821
    2881
    2941
    3001
    3061
    3121
    3181
    3241
    3301
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    3421
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    3541
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    4681
    4741
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    4921
    4981
    5041
    5101
    5161
    5221
    5281
    5341
    ATATTTTTTAGACGTCAGAAGGGTGAATATAGAGAAACAGACCGAGTAACTCGGTTCAAA
    TTAATCAAATCAGGGAAGCATTGGCTACGGGCCTCGACTTCTCTTTTTGGCTTGTTTAAG
    GTCTTGCGAGGTGGTGTTGATACTACTCAGGTCGTGACCGAAACGGTAGAAGATAAAGTA
    AGTCATTCAATTACTGGGCTTGATATCCTCAAGGGGATAGTTGCTGCGGGAACTGTCATA
    AGTGGAACCGTTGCAACTCAAACGAAGGTATTTACAAATGAGTCAGCAGTACTTGAAAAA
    ACTGTAGAGAAAACGGATGCTTTGGCAACAAATGGTACAGTAGTTCTAGGTACGATATCT
    ACAAGTAATTCAGCGAGTTCAACTAGTTTGTCAGCTTCAGAGTCGGCAAGTACATCTGCA
    TCTGAGTCAGCCTCAACCAGCGCTTCGACCTCAGCGAGTACAAGTGCATCAGAATCAGCA
    AGTACATCGGATTCGACAAGTATCTCTGCATCATCTACTGTGGTAGGATCACAAACAGCT
    GCCGCTACAGAAGCAACTGCTAAGAAGGTCGAAGAAGATCGTAAGAAACCAGCTAGTGAT
    TATGCAGCATCAGTTACAAATGTCAATCTCCAATCTTATGCTAAGCGACGCAAGCGTTCA
    GTGGATTCCATCGAGCAATTGCTGGCTTCTATAAATGCTGCTGTTTTTTCTGGCAATACG
    ACTGTAAATGGCGCCCCTGCAATTAATGCAAGTCTAAATATTGCTAAAAGTGAGACAAAA
    GTTTATACAGGTGAAGGTGTAGATTCGGTATATCGTGTTCCAATTTACTATCAATTGACA
    GTGATAAATGATGGTTCAAAATTGACCTTTACCTATACGGTTACGTATGTGAATCCTACA
    ACAAAGACTCTTGGTAGTATATCAAGGATGAGTAATGGATATTCTATCTATAATTCAGGT
    ACTTCAATACAAACAATGTTAACCCTTGGCAGTGGTCTTGGTAAACCTTCAGGTGTAAAG
    AACTACATTACTGACAAAAATGGTAGACAGGTTCGATCCTATAATACATCTACAATGACG
    ACGCATGGTAGTGGGTATACTTGGGGAAATGGTGCCCAAATGAATGGTTTCTTTGCTAAG
    CAAGGATATGGATTAACATCATCTTGGACTGTACCAATTAATGGAACGGATACATCCTTT
    ACATTTACCCCTTACGCTGCTAGAACAGATAGAATTGGAATTAACTACTTCAATGGTGGA
    GGAAAGGTAGTTGAATCTAGCACGACCAGTCAGTCACTTTCACAGTCTAAGTCACTCTCA
    GTAAGTGCTAGTCAAAGCGCCTCGGCTTCAGCGTCAACGAGTGCCTCAGCATCAGCAAGT
    ACCAGTGCGTCAGCCTCAGCAAGCACCAGTGCATCAGCCTCAGCAAGTACAAGCGCCTCA
    GCTTCAGCATCAACGAGTGCTTCGGCTTCAGCGTCAACCAGTGCGTCTGAATCGGCCTCA
    ACCAGTGCTTCGGCTTCAGCCTCAACCAGCGCAAGTACGTCAGCGTCAACGAGTGCCTCA
    GCTTCAGCATCAATAAGTGCGTCGGCTTCAGCAAGTACCAGCGCCTCGGCTTCATCAAGC
    ACATCAGCATCTGAATCAGCGTCAACGAGTGCTTCAGTCTCAGCATCGACAAGCGCTTCA
    GCTTCAGCAAGTACCTCAGCGTCTGAATCGGCCTCAACAAGTGCATCGGCTTCAGCAAGC
    ACAAGCGCCTCAGCCTCAGCAAGCACAAGCGCCTCAGCTTCAGCAAGTATCTCAGCGTCT
    GAATCGGCATCAACGAGTGCCTCTGAATCGGCATCAACCAGTGCATCAGCCTCTGCAAGT
    ACCAGTGCGTCAGCTTCAGCATCAACGAGTGCGTCGGCTTCCGCATCAACCAGTGCGTCG
    GCTTCCGCATCAACAAGCGCCTCGGCTTCAGCAAGCACAAGTGCGTCAGTCTCAGCATCA
    ACGAGTGCGTCAGCTTCAGCAAGCACCTCAGCGTCTGAATCTGCATCGACAAGCGCCTCG
    GCTTCAGCGTCAACGAGTGCGTCGGCTTCAGCAAGTACCAGTGCGTCAGCTTCAGCAAGC
    ACCTCAGCGTCTGAATCTGCATCGACAAGCGCCTCGGCTTCAGCGTCAACGAGTGCGTCG
    GCTTCAGCAAGTACCAGTGCGTCAGCTTCAGCAAGCACCTCAGCGTCTGAATCTGCATCG
    ACAAGCGCTTCAGCTTCAGCATCAACGAGTGCGTCGGCTTCAGCAAGTACAAGTGCCTCT
    GAATCGGCATCAACCAGTGCTTCAGCCTCAGCATCGACAAGCGCTTCGGCTTCAGCAAGT
    ACAAGTGCGTCTGAGTCAGCATCAACAAGTGCGTCTGAATCCGCATCAACGTCTGCCTCA
    GCCTCAGCGTCAACCAGTGCCTCAGCCTCAGCATCGACAAGCGCCTCAGCTTCAGCAAGC
    ACAAGTGCATCAGCTTCAGCAAGCACAAGTGCATCAGCTTCAGCAAGCACAAGCGCCTCA
    GCTTCAGCGTCAACAAGTGCGTCAGCTTCCGCATCAACGAGTGCCTCTGAATCGGCATCA
    ACGAGTGCCTCTGAATCTGCATCAACCAGTGCATCAGCCTCTGCAAGTACCAGTGCGTCA
    GCTTCAGCATCAACGAGTGCGTCGGCTTCCGCATCAACCAGTGCGTCGGCTTCCGCATCA
    ACAAGCGCCTCGGCTTCAGCAAGCACAAGTGCGTCAGTCTCAGCATCAACGAGTGCGTCA
    GCTTCAGCAAGCACCTCAGCGTCTGAATCTGCATCGACAAGCGCCTCGGCTTCAGCGTCA
    ACGAGTGCGTCGGCTTCAGCAAGTACCAGTGCATCAGCCTCTGCAAGCACAAGTGCTTCA
    GTCTCAGCATCAACCAGTGCGTCAGCTTCAGCGTCAACGAGTGCGTCAGCTTCAGCAAGC
    ACCTCAGCGTCTGAATCTGCATCGACAAGCGCCTCGGCTTCAGCGTCAACGAGTGCGTCG
    GCTTCAGCAAGTACCAGTGCATCAGCCTCTGCAAGCACAAGTGCTTCAGTCTCAGCATCA
    ACCAGTGCGTCAGCTTCAGCGTCAACGAGTGCGTCGGCTTCTGCAAGCACAAGCGCCTCG
    GCTTCCGCATCAACGAGTGCCTCAGCTTCAGCATCAACGAGTGCGTCAGCTTCAGCGTCA
    ACGAGTGCGTCTGAGTCAGCATCGACAAGCGCTTCAGCTTCAGCATCAACGAGTGCGTCG
    GCTTCAGCAAGTACAAGTGCCTCTGAATCGGCATCAACCAGTGCTTCAGCCTCAGCATCG
    ACAAGCGCTTCGGCTTCAGCAAGTATCTCAGCGTCTGAATCGGCATCAACGAGTGCGTCA
    GCCTCAGCAAGTACTAGTGCATCAGCTTCAGCATCAACAAGCGCCTCAGCTTCAGCATCA
    ACCAGTGCATCGGCTTCAGCATCAACAAGTGCCTCGGCTTCAGCGTCAACGAGTGCGTCT
    GAGTCAGCATCAACGAGTGCGTCAGCCTCAGCAAGCACATCAGCTTCTGAATCTGCATCA
    ACCAGTGCGTCAGCCTCAGCATCGACAAGCGCCTCAGCTTCAGCAAGTACCAGTGCTTCG
    GCTTCCGCATCAACCAGTGCTTCAGCCTCAGCATCGACAAGCGCTTCAGCTTCAGCGTCG
    ACAAGTGCTTCAGCCTCAGCATCGACAAGCGCTTCAGCTTCAGCATCAACAAGTGCCTCG
    GCTTCAGCATCAACAAGTGCCTCGGCTTCAGCATCAACGAGTGCTTCAGCTTCAGCATCA
    ACAAGTGCTTCAGCTTCAGCAAGTACCAGTGCGTCGGCTTCAGCATCAACGAGTGCTTCA
    GTCTCAGCGTCAACCAGTGCCTCTGAATCCGCATCAACCAGTGCCTCGGCTTCAGCAAGC
    ACCAGTGCTTCGGCTTCAGCAAGTACTAGCGCCTCAGCCTCAGCATCAACCAGTGCATCA
    GCCTCAGCAAGTATCTCAGCGTCTGAATCGGCATCAACGAGTGCGTCAGTCTCAGCATCA
    ACGAGTGCCTCGGCTTCAGCAAGTACCAGTGCGTCAGCTTCAGCAAGCACAAGTGCTTCA
    GTCTCAGCGTCAACGAGTGCTTCGGCTTCAGCAAGTACCAGTGCGTCAGCTTCAGCAAGT
    ACCAGTGCGTCAGCCTCAGCAAGTACTAGTGCATCAGCTTCAGCATCAACGAGTGCTTCG
    GCTTCAGCAAGTACAAGTGCCTCAGCTTCAGCAAGTACCAGTGCGTCAGCTTCAGCCTCA
    ACAAGCGCCTCAGCTTCAGCATCAACAAGTGCATCGGCTTCAGCATCAACGAGTGCGTCA
    GCCTCAGCAAGCACATCAGCTTCTGAATCTGCATCAACCAGTGCGTCAGCCTCAGCAAGT
    ACCAGTGCATCAGAGTCAGCAAGTACCAGTGCGTCAGCTTCAGCGTCAACGAGTGCGTCA
    GCCTCAGCAAGCACCTCAGCGTCTGAATCGGCATCAACAAGTGCGTCGGCCTCAGCAAGT
    ACCAGTGCCTCATCCTCAGCAAGCACAAGTGCCTCAGCTTCAGCAAGTACAAGCGCCTCA
    GCCTCAGCCTCGACAAGTGCTTCGGCTTCAGCAAGCACAAGCGCCTCATCCTCAGCAAGC
    ACAAGTGCCTCAGCTTCAGCAAGTACAAGTGCGTCAACCTCAGCATCAACCAGTGCTTCG
    GCTTCAGCAGGTAAGTCAAGACAGCAATTGCCAAATACAGGTACAGAAGTTTCCAAGTCA
    TCTGTAGCAAGTATCTCAGCGTCTGAATCGGCATCAACGAGTGCGTCAGCCTCAGCAAGT
    ACTAGTGCATCAGCTTCAGCAAGCACCAGTGCGTCAGCTTCCGCATCAACGAGTGCGTCC
    GCTTCAGCAAGCACAAGTGCGTCAGCCTCAGCAAGTACCAGTGCATCAGAGTCAGCAAGT
    ACCAGTGCGTCAGCTTCCGCATCAACGAGTGCGTCCGCTTCAGCAAGCACAAGTGCCTCA
    GCCTCAGCAAGTACCAGTGCATCAGAGTCAGCAAGTACCAGTGCGTCAGCTTCAGCGTCA
    ACCAGCGCCTCAGCCTCAGCAAGTACCAGTGCTTCGGCCTCAGCATCGACCAGTGCGTCA
    GCCTCAGCAAGTACCTCAGCGTCTGAATCAGCATCAACCAGTGCCTCAGCTTCAGCGTCG
    ACAAGTGCGTCAGCTTCAGCAAGTACCTCAGTTTCAAATTCAGCAAACCATTCGAACTCA
    CAAGTTGGAAATACTTCTGGATCGACAGGTAAATCCCAAAAAGAATTGCCTAATACAGGT
    ACTGAGTCGTCAATTGGATCTGTGTTACTTGGAGTTCTAGCAGCTGTTACAGGTATTGGA
    TTGGTTGCGAAACGCCGTAAACGTGATGAAGAAGAGTAA
    60
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    5220
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    5340
    5379

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: AT689_RS11650
  • symbol: AT689_RS11650
  • description: accessory Sec-dependent serine-rich glycoprotein adhesin
  • length: 1792
  • theoretical pI: 4.81529
  • theoretical MW: 162043
  • GRAVY: -0.0355469

⊟Function[edit | edit source]

  • TIGRFAM:
    serine-rich repeat adhesion glycoprotein (TIGR04224; HMM-score: 69.4)
    and 2 more
    Cell structure Cell envelope Other LPXTG cell wall anchor domain (TIGR01167; HMM-score: 35.6)
    KxYKxGKxW signal peptide (TIGR03715; HMM-score: 29.7)
  • TheSEED:
  • PFAM:
    no clan defined Gram_pos_anchor; LPXTG cell wall anchor motif (PF00746; HMM-score: 53.2)
    and 1 more
    KxYKxGKxW_sig; KxYKxGKxW signal peptide (PF19258; HMM-score: 36.9)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cellwall
    • Cytoplasmic Score: 0.01
    • Cytoplasmic Membrane Score: 0.01
    • Cellwall Score: 9.97
    • Extracellular Score: 0.01
    • Internal Helices: 2
  • DeepLocPro: Cell wall & surface
    • Cytoplasmic Score: 0.0001
    • Cytoplasmic Membrane Score: 0.0207
    • Cell wall & surface Score: 0.9694
    • Extracellular Score: 0.0098
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.032521
    • TAT(Tat/SPI): 0.006058
    • LIPO(Sec/SPII): 0.002901
  • predicted transmembrane helices (TMHMM): 1

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_078376735 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MFFRRQKGEYRETDRVTRFKLIKSGKHWLRASTSLFGLFKVLRGGVDTTQVVTETVEDKVSHSITGLDILKGIVAAGTVISGTVATQTKVFTNESAVLEKTVEKTDALATNGTVVLGTISTSNSASSTSLSASESASTSASESASTSASTSASTSASESASTSDSTSISASSTVVGSQTAAATEATAKKVEEDRKKPASDYAASVTNVNLQSYAKRRKRSVDSIEQLLASINAAVFSGNTTVNGAPAINASLNIAKSETKVYTGEGVDSVYRVPIYYQLTVINDGSKLTFTYTVTYVNPTTKTLGSISRMSNGYSIYNSGTSIQTMLTLGSGLGKPSGVKNYITDKNGRQVRSYNTSTMTTHGSGYTWGNGAQMNGFFAKQGYGLTSSWTVPINGTDTSFTFTPYAARTDRIGINYFNGGGKVVESSTTSQSLSQSKSLSVSASQSASASASTSASASASTSASASASTSASASASTSASASASTSASASASTSASESASTSASASASTSASTSASTSASASASISASASASTSASASSSTSASESASTSASVSASTSASASASTSASESASTSASASASTSASASASTSASASASISASESASTSASESASTSASASASTSASASASTSASASASTSASASASTSASASASTSASVSASTSASASASTSASESASTSASASASTSASASASTSASASASTSASESASTSASASASTSASASASTSASASASTSASESASTSASASASTSASASASTSASESASTSASASASTSASASASTSASESASTSASESASTSASASASTSASASASTSASASASTSASASASTSASASASTSASASASTSASASASTSASESASTSASESASTSASASASTSASASASTSASASASTSASASASTSASASASTSASVSASTSASASASTSASESASTSASASASTSASASASTSASASASTSASVSASTSASASASTSASASASTSASESASTSASASASTSASASASTSASASASTSASVSASTSASASASTSASASASTSASASASTSASASASTSASASASTSASESASTSASASASTSASASASTSASESASTSASASASTSASASASISASESASTSASASASTSASASASTSASASASTSASASASTSASASASTSASESASTSASASASTSASESASTSASASASTSASASASTSASASASTSASASASTSASASASTSASASASTSASASASTSASASASTSASASASTSASASASTSASASASTSASASASTSASVSASTSASESASTSASASASTSASASASTSASASASTSASASASISASESASTSASVSASTSASASASTSASASASTSASVSASTSASASASTSASASASTSASASASTSASASASTSASASASTSASASASTSASASASTSASASASTSASASASTSASASASTSASESASTSASASASTSASESASTSASASASTSASASASTSASESASTSASASASTSASSSASTSASASASTSASASASTSASASASTSASSSASTSASASASTSASTSASTSASASAGKSRQQLPNTGTEVSKSSVASISASESASTSASASASTSASASASTSASASASTSASASASTSASASASTSASESASTSASASASTSASASASTSASASASTSASESASTSASASASTSASASASTSASASASTSASASASTSASESASTSASASASTSASASASTSVSNSANHSNSQVGNTSGSTGKSQKELPNTGTESSIGSVLLGVLAAVTGIGLVAKRRKRDEEE

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Expression data[edit | edit source]

  • PneumoExpress for strain D39V:

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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