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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 11-FEB-2025

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae SPN032672
  • locus tag: SPN032672_RS13250
  • pan locus tag?: PNEUPAN003225000
  • symbol: SPN032672_RS13250
  • pan gene symbol?: psrP
  • synonym:
  • product: accessory Sec-dependent serine-rich glycoprotein adhesin

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPN032672_RS13250
  • symbol: SPN032672_RS13250
  • product: accessory Sec-dependent serine-rich glycoprotein adhesin
  • replicon: chromosome
  • strand: -
  • coordinates: 685967..690259
  • length: 4293
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: NC_021003 (685967..690259) NCBI
  • BioCyc:
  • MicrobesOnline:
  • PneumoBrowse for strain D39V:

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    1441
    1501
    1561
    1621
    1681
    1741
    1801
    1861
    1921
    1981
    2041
    2101
    2161
    2221
    2281
    2341
    2401
    2461
    2521
    2581
    2641
    2701
    2761
    2821
    2881
    2941
    3001
    3061
    3121
    3181
    3241
    3301
    3361
    3421
    3481
    3541
    3601
    3661
    3721
    3781
    3841
    3901
    3961
    4021
    4081
    4141
    4201
    4261
    ATATTTTTTAGACGTCAGAAGGGTGAATATAGAGAAACAGACCGAGTAACTCGGTTCAAA
    TTAATCAAATCAGGGAAGCATTGGCTACGGGCCTCGACTTCTCTTTTTGGCTTGTTTAAG
    GTCATGCGTGGTGGTGTTGATACTACTCAGGTCATGACCGAAACGGTAGAAGATAAAGTA
    AGTCATTCAATTACTGGGCTTGATATCCTCAAGGGAATAGTTGCTGCGGGAACTGTCATA
    AGTGGAACCGTTGCAACTCAAACGAAGGTATTTACAAATGAGTCGGCAGTACTTGAAAAA
    ACTGTAGAGAAAACGGATGCTTTGGCAACAAATGATACAGTAGTTCTAGGTACGATATCT
    ACAAGTAATTCAGCGAGTTCAACTAGTTTGTCAGCTTCAGAGTCGGCAAGTACATCTGCA
    TCTGAGTCAGCCTCAACCAGCGCTTCGACCTCAGCGAGTACAAGTGCATCAGAATCAGCA
    AGTACATCGGCTTCGACAAGTATCTCTGCATCATCTACTGTGGTAGGATCACAAACAGCT
    GCCGCTACAGAAGCAACTGCTAAGAAGGTCGAAGAAGATCGTAAGAAACCAGCTAGTGAT
    TATGCAGCATCAGTTACAAATGTCAATCTCCAATCTTATGCTAAGCGACGCAAGCGTTCA
    GTGGATTCCATCGAGCAATTGCTGGCTTCTATAAAAGCTGCTGTTTTTTCTGGCAATACG
    ATTGTAAATGGCGCCCCTGCAATTAATGCAAGTCTAAACATTGCTAAAAGTGAGACAAAA
    GTTTATACAGGTACAGGTTTAGATTCGGTATATCATGTTCCAATTTACTATAAATTGACA
    GTGACAAATGATGGTTCAAAACTGACCTTTACCTATACGGTTACGTATGTAGATCCTACC
    ACAAGGGCTCTTGGTAATCTTTCAAAGATGGGTCATGGGTATTCTATCTATAATACAGGT
    ACTTCAATACAAACAATGTTAACCCTTGGCAGTGATCTTGGTACCCCTTCAGATGTAAAG
    AACTACATTACTGACAAAGATGGTGTACTGGTTCGATCCTATAATACATCTACAATGACG
    ACGTGGGGTAGTGGGTATACTTGGGGAAATGGTGCCCAAATGAATGGTTTCTTTGCTAAG
    CAAGGATATGGATTAACATCATCTTGGACTGTACCAATTACTGGAACGGATACATCCTTT
    ACATTTACCCCTTACGCTGCTAAAACAGATAACATTAGAACTAACTACTTCAAGGGTAGA
    GGAAAGGTAGTTGAATCTAGCACGACCAGTCAGTCACTTTCACAGTCTAAGTCACTCTCA
    GTAAGTGCTAGTCAAAGCGCCTCAGCCTCAGCAAGCACCTCAGCTTCTGAATCGGCCTCA
    ACCAGCGCATCAGCCTCAGCAAGTACAAGTGCCTCAGCCTCAGCATCAACGAGTGCGTCA
    GCTTCCGCATCAACGAGTGCCTCAGCTTCAGCAAGTACCTCAGCGTCTGAATCTGCATCA
    ACGAGTGCGTCAGCTTCCGCATCAACGAGTGCGTCGGCTTCAGCAAGCACTAGCGCCTCG
    GCTTCAGCAAGCACCAGTGCGTCGGCTTCAGCAAGTACCAGTGCTTCGGCCTCAGCGTCA
    ACCAGTGCATCAGCTTCAGCGTCAACCAGTGCGTCAGCTTCAGCAAGTACCTCAGCGTCT
    GAATCTGCATCAACGAGTGCGTCAGCTTCCGCATCAACGAGTGCGTCGGCTTCAGCAAGC
    ACTAGCGCCTCGGCTTCAGCAAGCACCAGTGCGTCGGCTTCAGCAAGTACCAGTGCTTCG
    GCCTCAGCGTCAACCAGTGCATCAGCTTCAGCGTCAACCAGTGCGTCAGCTTCAGCAAGT
    ACCTCAGCGTCTGAATCGGCCTCAACCAGTGCATCTGAATCGGCATCAACCAGTGCCTCA
    GCCTCAGCAAGTACTAGCGCCTCAGCTTCAGCATCAACGAGTGCATCAGCTTCCGCATCA
    ACAAGTGCATCAGCTTCCGCATCAACGAGTGCATCGGCTTCAGCAAGCACAAGTGCGTCA
    GCCTCAGCAAGTACCAGTGCATCAGAGTCAGCAAGTACCAGTGCTTCAGCTTCAGCATCA
    ACGAGTGCGTCCGCTTCAGCAAGCACAAGTGCGTCAGCCTCAGCAAGTACCAGTGCATCA
    GAGTCAGCAAGTACTAGCGCCTCAGCCTCAGCCTCAACCAGCGCGTCAGCTTCAGCGTCA
    ACCAGTGCATCAGCTTCAGCGTCAACCAGTGCTTCAGCTTCAGCGTCGACAAGTGCGTCA
    GCCTCAGCATCGACAAGCGCTTCAGCTTCAGCCTCAACGAGTGCGTCGGCTTCAGCAAGC
    ACAAGCGCCTCAGCTTCCGCATCAACCAGTGCGTCAGCCTCAGCAAGCACAAGTGCGTCT
    GAATCTGCATCAACGAGTGCGTCAGCCTCAGCATCAACAAGTGCCTCAGCTTCATCAAGC
    ACAAGCGCATCAGCCTCAGCATCAACAAGCGCCTCAGCTTCAGCGTCAACCAGTGCCTCG
    GCTTCAGCATCAACGAGTGCGTCAGCTTCAGCCTCAACGAGTGCGTCTGAGTCAGCCTCA
    ACGAGTGCGTCGGCTTCAGCAAGTACCAGTGCTTCGGCCTCAGCAAGCACAAGTGCGTCT
    GAATCCGCATCAACGTCTGCCTCAGCCTCAGCATCGACAAGCGCTTCAGCTTCAGCGTCG
    ACAAGTGCGTCAGCCTCAGCATCGACAAGCGCTTCAGCTTCAGCGTCGACAAGTGCTTCG
    GCTTCAGCAAGCACCAGTGCCTCGGCTTCAGCGTCGACAAGTGCCTCAGCTTCAGCAAGT
    ACCAGTGCGTCAGCCTCAGCATCAACGAGTGCGTCGGCTTCAGCATCAACGAGTGCATCA
    GCTTCAGCATCAACGAGTGCGTCGGCTTCAGCAAGCACATCAGCTTCTGAATCAGCATCA
    ACCAGTGCATCAGCCTCAGCAAGCACCAGTGCGTCGGCTTCAGCAAGTACAAGTGCGTCA
    GCCTCAGCATCAACAAGTGCCTCAGCTTCAGCCTCAGCAAGTATCTCAGCGTCTGAATCT
    GCATCAACCAGTGCGTCAGCATCCGCATCAACGAGTGCATCAGCTTCAGCAAGCACCAGT
    GCTTCAGCTTCAGCATCAACCAGTGCCTCAGCTTCGGCCTCAACAAGTGCGTCAGCTTCA
    GCAAGCACCAGTGCTTCGGCTTCAGCGTCGACAAGTGCGTCAACCTCAGCAAGTACAAGT
    GCATCGGCTTCAGCAAGCACCAGTGCTTCGGCTTCAGCAAGCACGTCAGCATCAACAAGC
    ACAAGTACATCGGCAAGCACGTCAGCATCGACAAGTGCAAGCACATCGGCGTCAACAAGT
    GCAAGTACGTCAGCATCTGAATCGGCCTCAACCAGTGCGTCGACTTCAGCAAGTACAAGC
    GCCTCAGCCTCAGCAAGTATCTCAGCGTCTGAATCGGCATCAACCAGCGCCTCAGCCTCA
    GCATCAACAAGTGCATCAGCTTCAGCAAGCACCTCAGCGTCTGAATCGGCATCAACGAGT
    GCCTCAGCTTCAGCAAGCACCAGTACCTCAGCTTCTGAATCGGCCTCAACCAGTGCCTCA
    GCTTCAGCGTCAACCAGTGCCTCAGCTTCTGCATCAACCAGCGCCTCGGCCTCAGCAAGC
    ACCTCAGCATCTGAATCCGCATCAACGAGTACCTCAGCTTCTGAATCGGCCTCAACAAGT
    GCCTCGGCCTCAGCAAGCACAAGCGCCTCAGCTTCAGCAAGTACCAGTGCGTCAGCTTCC
    GCATCAACGAGTGCTTCGGCTTCAGCCTCAACGAGTGCCTCAGCTTCAGCGTCAACCAGT
    GCTTCAGCCTCAGCATCAACGAGTGCTTCGGCTTCAGCAAGTACCAGTGCTTCGGCCTCA
    GCATCGACAAGTGCCTCAGCTTCAGCAAGTACTAGCGCCTCAGCCTCAGCATCAACCAGT
    GCCTCGGCTTCAGCAAGTACTAGCGCCTCAGCTTCAGCGTCAACCAGTGCCTCAGCATCA
    GCAAGCACCTCAGCGTCTGAATCGGCATCAACCAGTGCGTCTGAGTCAGCATCAACGAGT
    GCGTCAGCCTCAGCAAGTACATCAGTTTCAAATTCAGCAAACCATTCGAACTCACAAGTT
    GGAAATGCTTCTGGATCGACAGGTAAATCCCAAAAAGAATTGCCTAATACAGGTACTGAG
    TCGTCAATTGGATCTGTGTTACTTGGAGTTCTAGCAGCTGTTACAGGTATTGGATTGGTT
    GCGAAACGCCGTAAACGTGATGAAGAAGAGTAA
    60
    120
    180
    240
    300
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    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
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    1260
    1320
    1380
    1440
    1500
    1560
    1620
    1680
    1740
    1800
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    1920
    1980
    2040
    2100
    2160
    2220
    2280
    2340
    2400
    2460
    2520
    2580
    2640
    2700
    2760
    2820
    2880
    2940
    3000
    3060
    3120
    3180
    3240
    3300
    3360
    3420
    3480
    3540
    3600
    3660
    3720
    3780
    3840
    3900
    3960
    4020
    4080
    4140
    4200
    4260
    4293

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPN032672_RS13250
  • symbol: SPN032672_RS13250
  • description: accessory Sec-dependent serine-rich glycoprotein adhesin
  • length: 1430
  • theoretical pI: 5.16853
  • theoretical MW: 131221
  • GRAVY: -0.0668531

⊟Function[edit | edit source]

  • TIGRFAM:
    serine-rich repeat adhesion glycoprotein (TIGR04224; HMM-score: 67.3)
    and 2 more
    KxYKxGKxW signal peptide (TIGR03715; HMM-score: 29.9)
    Cell structure Cell envelope Other LPXTG cell wall anchor domain (TIGR01167; HMM-score: 28.5)
  • TheSEED:
  • PFAM:
    no clan defined Gram_pos_anchor; LPXTG cell wall anchor motif (PF00746; HMM-score: 48.2)
    and 1 more
    KxYKxGKxW_sig; KxYKxGKxW signal peptide (PF19258; HMM-score: 37.3)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cellwall
    • Cytoplasmic Score: 0.02
    • Cytoplasmic Membrane Score: 0.74
    • Cellwall Score: 9.24
    • Extracellular Score: 0
    • Internal Helix: 1
  • DeepLocPro: Cell wall & surface
    • Cytoplasmic Score: 0.0002
    • Cytoplasmic Membrane Score: 0.0082
    • Cell wall & surface Score: 0.9869
    • Extracellular Score: 0.0047
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.028946
    • TAT(Tat/SPI): 0.007405
    • LIPO(Sec/SPII): 0.002248
  • predicted transmembrane helices (TMHMM): 1

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_231852905 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MFFRRQKGEYRETDRVTRFKLIKSGKHWLRASTSLFGLFKVMRGGVDTTQVMTETVEDKVSHSITGLDILKGIVAAGTVISGTVATQTKVFTNESAVLEKTVEKTDALATNDTVVLGTISTSNSASSTSLSASESASTSASESASTSASTSASTSASESASTSASTSISASSTVVGSQTAAATEATAKKVEEDRKKPASDYAASVTNVNLQSYAKRRKRSVDSIEQLLASIKAAVFSGNTIVNGAPAINASLNIAKSETKVYTGTGLDSVYHVPIYYKLTVTNDGSKLTFTYTVTYVDPTTRALGNLSKMGHGYSIYNTGTSIQTMLTLGSDLGTPSDVKNYITDKDGVLVRSYNTSTMTTWGSGYTWGNGAQMNGFFAKQGYGLTSSWTVPITGTDTSFTFTPYAAKTDNIRTNYFKGRGKVVESSTTSQSLSQSKSLSVSASQSASASASTSASESASTSASASASTSASASASTSASASASTSASASASTSASESASTSASASASTSASASASTSASASASTSASASASTSASASASTSASASASTSASASASTSASESASTSASASASTSASASASTSASASASTSASASASTSASASASTSASASASTSASASASTSASESASTSASESASTSASASASTSASASASTSASASASTSASASASTSASASASTSASASASTSASESASTSASASASTSASASASTSASASASTSASESASTSASASASTSASASASTSASASASTSASASASTSASASASTSASASASTSASASASTSASASASTSASASASTSASESASTSASASASTSASASSSTSASASASTSASASASTSASASASTSASASASTSASESASTSASASASTSASASASTSASESASTSASASASTSASASASTSASASASTSASASASTSASASASTSASASASTSASASASTSASASASTSASASASTSASASASTSASASASTSASESASTSASASASTSASASASTSASASASTSASASASASISASESASTSASASASTSASASASTSASASASTSASASASTSASASASTSASASASTSASTSASTSASASASTSASASASTSASTSTSTSASTSASTSASTSASTSASTSASESASTSASTSASTSASASASISASESASTSASASASTSASASASTSASESASTSASASASTSTSASESASTSASASASTSASASASTSASASASTSASESASTSTSASESASTSASASASTSASASASTSASASASTSASASASTSASASASTSASASASTSASASASTSASASASTSASASASTSASASASTSASASASTSASASASTSASASASTSASESASTSASESASTSASASASTSVSNSANHSNSQVGNASGSTGKSQKELPNTGTESSIGSVLLGVLAAVTGIGLVAKRRKRDEEE

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Expression data[edit | edit source]

  • PneumoExpress for strain D39V:

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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