From PneumoWiki
Jump to navigation Jump to search
PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 09-DEC-2016

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae SP49
  • locus tag: BMJ42_00186 [new locus tag: BMJ42_RS00960 ]
  • pan locus tag?: PNEUPAN000707000
  • symbol: BMJ42_00186
  • pan gene symbol?: epsH
  • synonym:
  • product: glycosyltransferase involved in cell wall biogenesis

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: BMJ42_00186 [new locus tag: BMJ42_RS00960 ]
  • symbol: BMJ42_00186
  • product: glycosyltransferase involved in cell wall biogenesis
  • replicon: chromosome
  • strand: +
  • coordinates: 154702..155151
  • length: 450
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: CP018136 (154702..155151) NCBI
  • BioCyc: see BMJ42_RS00960
  • MicrobesOnline:
  • PneumoBrowse for strain D39V:

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    ATGAAGTTATTGTCTATCGCCATTTCTAGCTATAATGCAGCAGCCTATCTTCATTACTGT
    GTGGAGTCGCTAGTGATTGGTGGTGAGCAAGTTGAGATTTTGATTATCAATGACGGGTCT
    CAGGATCAGACTCAGGAAATCGCTGAGTGTTTAGCTAGCAAGTATCCTAACATCGTTAGA
    GCCATCTATCAGGAAAATAAAGGCCATGGCGGTGTGGTCAATTGCGGTTTGGCAGAGGCT
    TCTGGGCGCTATTTTAAAGTAGTTGACAGTGATGACTGGGTGGATCCTCGTGCCTACTTG
    AAAATTCTTGAAACCTTGCAGGAACTTGAGAGCAAGGGTCAAGAGGTGGATGCCTTTGTG
    ACCAATTTTGTCTATGAAAAGGAAGGTCAGTCTCGTAAGAAGAGTATGAGTTACGAGTCA
    GTCTTGCCTGTTCGGCAGATTTTTGACTAG
    60
    120
    180
    240
    300
    360
    420
    450

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: BMJ42_00186 [new locus tag: BMJ42_RS00960 ]
  • symbol: BMJ42_00186
  • description: glycosyltransferase involved in cell wall biogenesis
  • length: 149
  • theoretical pI: 4.4683
  • theoretical MW: 16677.7
  • GRAVY: -0.209396

⊟Function[edit | edit source]

  • TIGRFAM:
    poly-beta-1,6 N-acetyl-D-glucosamine synthase (TIGR03937; EC 2.4.1.-; HMM-score: 50.5)
    and 7 more
    Unknown function Enzymes of unknown specificity transferase 2, rSAM/selenodomain-associated (TIGR04283; EC 2.-.-.-; HMM-score: 36.1)
    putative glycosyltransferase, exosortase G-associated (TIGR03111; HMM-score: 34.6)
    mycofactocin system glycosyltransferase (TIGR03965; HMM-score: 26.2)
    glycosyltransferase, TIGR04182 family (TIGR04182; HMM-score: 21.2)
    colanic acid biosynthesis glycosyltransferase WcaE (TIGR04009; EC 2.4.-.-; HMM-score: 18.4)
    colanic acid biosynthesis glycosyltransferase WcaA (TIGR04017; EC 2.4.-.-; HMM-score: 17)
    hopene-associated glycosyltransferase HpnB (TIGR03469; HMM-score: 13.3)
  • TheSEED: data available for D39
  • PFAM:
    GT-A (CL0110) Glycos_transf_2; Glycosyl transferase family 2 (PF00535; HMM-score: 83.7)
    and 4 more
    Glyco_tranf_2_3; Glycosyltransferase like family 2 (PF13641; HMM-score: 38.3)
    Glyco_tranf_2_2; Glycosyltransferase like family 2 (PF10111; HMM-score: 23)
    Glyco_tranf_2_4; Glycosyl transferase family 2 (PF13704; HMM-score: 13.4)
    no clan defined BSD; BSD domain (PF03909; HMM-score: 12.2)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 1.05
    • Cytoplasmic Membrane Score: 8.78
    • Cellwall Score: 0.08
    • Extracellular Score: 0.09
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.4594
    • Cytoplasmic Membrane Score: 0.3271
    • Cell wall & surface Score: 0.004
    • Extracellular Score: 0.2094
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.150498
    • TAT(Tat/SPI): 0.000748
    • LIPO(Sec/SPII): 0.018635
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: APJ29528 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MKLLSIAISSYNAAAYLHYCVESLVIGGEQVEILIINDGSQDQTQEIAECLASKYPNIVRAIYQENKGHGGVVNCGLAEASGRYFKVVDSDDWVDPRAYLKILETLQELESKGQEVDAFVTNFVYEKEGQSRKKSMSYESVLPVRQIFD

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Expression data[edit | edit source]

  • PneumoExpress for strain D39V:

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

Retrieved from "http://pneumowiki.med.uni-greifswald.de/index.php?title=BMJ42_00186&oldid=133233"