PangenomeTIGR4

serotype 4

D39

serotype 2

D39V

serotype 2

Hungary19A-6

serotype 19A

EF3030

serotype 19F

670-6B

serotype 6B

6A-10

serotype 6A

70585

serotype 5

A026

serotype 19F

A66

serotype 3

AP200

serotype 11A

ASP0581

serotype 12F

ATCC 49619

serotype 19F

ATCC 700669

serotype 23F

BVJ1JL

serotype 1

CGSP14

serotype 14

G54

serotype 19F

HU-OH

serotype 3

Hu15

serotype 19A

Hu17

serotype 19A

INV104

serotype 1

INV200

serotype 14

JJA

serotype 14

MDRSPN001

serotype 19F

NCTC7466

serotype 2

NU83127

serotype 4

OXC141

serotype 3

P1031

serotype 1

R6

serotype 2

SP49

serotype 19A

SPN032672

serotype 1

SPN034156

serotype 3

SPN034183

serotype 3

SPN994038

serotype 3

SPN994039

serotype 3

SPNA45

serotype 3

ST556

serotype 19F

TCH8431/19A

serotype 19A

Taiwan19F-14

serotype 19F

Xen35

serotype 4

gamPNI0373

serotype 1

NCBI: 09-DEC-2016

⊟Summary

• organism: Streptococcus pneumoniae SP49
• locus tag: BMJ42_00196 [new locus tag: BMJ42_RS01030 ]
• pan locus tag^?: PNEUPAN000756000
• symbol: ugpB
• pan gene symbol^?: ABC-SBP_1
• synonym:
• product: ABC transporter substrate-binding protein, UgpB

⊟Genome View

⊟Gene

⊟General

• type: CDS
• locus tag: BMJ42_00196 [new locus tag: BMJ42_RS01030 ]
• symbol: ugpB
• product: ABC transporter substrate-binding protein, UgpB
• replicon: chromosome
• strand: +
• coordinates: 165124..166599
• length: 1476
• essential: unknown

⊟Accession numbers

• Location: CP018136 (165124..166599) NCBI
• BioCyc: see BMJ42_RS01030
• MicrobesOnline:
• PneumoBrowse for strain D39V: SPV_0090 PneumoBrowse

⊟Phenotype

Share your knowledge and add information here. [edit]

⊟DNA sequence

• 1
  61
  121
  181
  241
  301
  361
  421
  481
  541
  601
  661
  721
  781
  841
  901
  961
  1021
  1081
  1141
  1201
  1261
  1321
  1381
  1441
  
  ATGAAAAACTGGAAAAAATATGCTTTTGCATCTGCTAGTGTAGTCGCTCTGGCTGCAGGT
  CTTGCTGCTTGTGGAAATTTGACAGGTAACAGCAAAAAAGCTGCTGATTCAGGTGACAAA
  CCTGTTATCAAAATGTACCAAATCGGTGACAAACCAGATAACTTGGATGAATTGTTAGCA
  AATGCCAACAAAATCATCGAAGAAAAAGTTGGTGCTAAATTGGATATCCAATACCTTGGC
  TGGGGTGACTATGGTAAGAAAATGTCAGTTATCACATCATCTGGTGAAAACTATGATATC
  GCCTTTGCAGATAACTATATTGTAAATGCTCAAAAAGGTGCTTATGCTGACTTGACAGAA
  TTGTACAAAAAAGAAGGTAAAGACCTTTACAAGGCACTTGATCCAGCTTATATCAAGGGT
  AATACTGTAAATGGTAAGATTTACGCTGTACCAGTTGCAGCCAACGTAGCATCATCTCAA
  AACTTTGCCTTCAACGGAACTCTCCTTGCCAAATATGGTATCGATATTTCAGGTGTTACT
  TCTTACGAAACTCTTGAGCCAGTCTTGAAACAAATCAAAGAAAAAGCTCCAGACGTAGTA
  CCATTTGCTATTGGTAAAGTTTTCATCCCATCTGATAACTTTGACTACCCAGTAGCAAAC
  GGTCTTCCATTCGTTATTGACCTTGAAGGCGATACTACTAAAGTTGTAAACCGTTACGAA
  GTACCTCGTTTCAAAGAACACTTGAAGACTCTTCACAAATTCTATGAAGCTGGCTACATT
  CCAAAAGACGTCGCAACAAGCGATACTTCCTTTGACCTTCAACAAGATACTTGGTTCGTT
  CGTGAAGAAACAGTAGGACCAGCTGACTACGGTAACAGCTTGCTTTCACGTGTTGCCAAC
  AAAGATATCCAAATCAAACCAATTACTAACTTCATCAAGAAAAACCAAACAACACAAGTT
  GCTAACTTTGTCATCTCAAACAACTCTAAGAACAAAGAAAAATCAATGGAAATCTTGAAC
  CTCTTGAATACGAACCCAGAACTCTTGAACGGTCTTGTTTACGGTCCAGAAGGCAAGAAC
  TGGGAAAAAATTGAAGGTAAAGAAAACCGTGTTCGCGTTCTTGATGGCTACAAAGGAAAC
  ACTCACATGGGTGGATGGAACACTGGTAACAACTGGATCCTTTACATCAACGAAAACGTT
  ACAGACCAACAAATCGAAAATTCTAAGAAAGAATTGGCAGAAGCTAAAGAATCTCCAGCG
  CTTGGATTTATCTTTAATACTGACAATGTGAAATCTGAAATCTCAGCTATTGCTAACACA
  ATGCAACAATTTGATACAGCTATCAACACTGGTACTGTAGACCCAGATAAAGCGATTCCA
  GAATTGATGGAAAAATTGAAATCTGAAGGTGCCTACGAAAAAGTATTGAACGAAATGCAA
  AAACAATACGATGAATTCTTGAAAAACAAAAAATAA
  60
  120
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  240
  300
  360
  420
  480
  540
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  840
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  960
  1020
  1080
  1140
  1200
  1260
  1320
  1380
  1440
  1476
  

⊟Protein

⊟General

• locus tag: BMJ42_00196 [new locus tag: BMJ42_RS01030 ]
• symbol: UgpB
• description: ABC transporter substrate-binding protein, UgpB
• length: 491
• theoretical pI: 5.30604
• theoretical MW: 54485.2
• GRAVY: -0.470468

⊟Function

• TIGRFAM:
• TheSEED: data available for D39, Hungary19A-6, TIGR4
• PFAM:
  no clan defined DUF3502; Domain of unknown function (DUF3502) (PF12010; HMM-score: 118)
  and 2 more
  Mak16; Mak16 protein C-terminal region (PF04874; HMM-score: 12)
  LppaM (CL0421) LPAM_2; Prokaryotic lipoprotein-attachment site (PF13627; HMM-score: 9.3)

⊟Structure, modifications & cofactors

• domains:
• modifications:
• cofactors:
• effectors:

⊟Localization

• PSORTb: unknown (no significant prediction)
  • Cytoplasmic Score: 2.5
  • Cytoplasmic Membrane Score: 2.5
  • Cellwall Score: 2.5
  • Extracellular Score: 2.5
  • Internal Helix: 1
• SignalP: Signal peptide LIPO(Sec/SPII) length 23 aa
  • SP(Sec/SPI): 0.00546
  • TAT(Tat/SPI): 0.000164
  • LIPO(Sec/SPII): 0.994125
  • Cleavage Site: CS pos: 23-24. LAA-CG. Pr: 0.9945
• predicted transmembrane helices (TMHMM): 1

⊟Accession numbers

• GI:
• RefSeq: APJ29538 NCBI
• UniProt:

⊟Protein sequence

• MKNWKKYAFASASVVALAAGLAACGNLTGNSKKAADSGDKPVIKMYQIGDKPDNLDELLANANKIIEEKVGAKLDIQYLGWGDYGKKMSVITSSGENYDIAFADNYIVNAQKGAYADLTELYKKEGKDLYKALDPAYIKGNTVNGKIYAVPVAANVASSQNFAFNGTLLAKYGIDISGVTSYETLEPVLKQIKEKAPDVVPFAIGKVFIPSDNFDYPVANGLPFVIDLEGDTTKVVNRYEVPRFKEHLKTLHKFYEAGYIPKDVATSDTSFDLQQDTWFVREETVGPADYGNSLLSRVANKDIQIKPITNFIKKNQTTQVANFVISNNSKNKEKSMEILNLLNTNPELLNGLVYGPEGKNWEKIEGKENRVRVLDGYKGNTHMGGWNTGNNWILYINENVTDQQIENSKKELAEAKESPALGFIFNTDNVKSEISAIANTMQQFDTAINTGTVDPDKAIPELMEKLKSEGAYEKVLNEMQKQYDEFLKNKK

⊟Experimental data

• protein localization:
• interaction partners:

⊟Expression & Regulation

⊟Operon

⊟Regulation

• data available for TIGR4

⊟Expression data

• PneumoExpress for strain D39V: SPV_0090 PneumoExpress

⊟Biological Material

⊟Mutants

⊟Expression vector

⊟lacZ fusion

⊟GFP fusion

⊟two-hybrid system

⊟FLAG-tag construct

⊟Antibody

⊟Other Information

You are kindly invited to share additional interesting facts.

⊟Literature

⊟References

⊟Relevant publications