From PneumoWiki
Jump to navigation Jump to search
PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 08-MAR-2025

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae SP49
  • locus tag: BMJ42_RS07705 [old locus tag: BMJ42_01456 ]
  • pan locus tag?: PNEUPAN002786000
  • symbol: BMJ42_RS07705
  • pan gene symbol?: bepA
  • synonym:
  • product: tetratricopeptide repeat protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: BMJ42_RS07705 [old locus tag: BMJ42_01456 ]
  • symbol: BMJ42_RS07705
  • product: tetratricopeptide repeat protein
  • replicon: chromosome
  • strand: -
  • coordinates: 1384716..1385945
  • length: 1230
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: NZ_CP018136 (1384716..1385945) NCBI
  • BioCyc: BMJ42_RS07705 BioCyc
  • MicrobesOnline:
  • PneumoBrowse for strain D39V: SPV_1331 PneumoBrowse

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    GTGAACAATAGTCAACAGATGTTACAGGCTTTGGAGGAGCAAGATTTAACTAAGGCTGAG
    CATTATTTCGCCAAAGCTTTAGAAAATGATTCAAGTGATCTTCTGTATGAGTTGGCAACT
    TATCTTGAAGGGATTGGTTTCTATCCTCAGGCCAAGGAAATTTACCTGAAAATTGTAGAG
    GATTTTCCAGAGGTTCATCTTAATCTAGCTGCAATTGCTAGCGAGGATGGTCAAATAGAA
    GAAGCCTTTACCTATCTTGAGGAAATCCAAGCTGACAGTGACTGGTATGTCTCGTCTTTG
    GCTCTGAAGGCAGACCTTTACCAGCTGGAAGGTTTGACAGATGTGGCACGTGAGAAATTA
    TTGGAGGCCTTGACCTACTCAGAGGATTCTCTCTTGATATTGGGTTTGGCAGAGTTGGAT
    AGTGAGTTGGAAAATTACCAAGCGGCTATTCAAGCCTATGCCCAGTTAGATAATCGCTCG
    ATTTATGAGCAAACGGGCATTTCCACCTATCAACGAATTGGCTTTGCCTATGCTCAGTTA
    GGGAAATTTGAAACGGCTACTGAGTTTTTAGAAAAAGCCCTGGAGTTAGAATACGATGAC
    TTAACAGCTTTTGAGTTGGCCAGTCTTTATTTTGATCAAGAAGAATATCAAAAAGCCACC
    CTCTACTTTAAGCAGCTTGATACCATTTCTCCTGACTTTGAAGGCTATGAGTATGGGTAC
    AGTCAGGCTTTACATAAGGAACATCAAGTTCAAGAAGCCCTGCGTATCGCTAAGCAAGGA
    TTAGAGAAAAATCCCTTTGAAACTCGCCTCTTGCTAGCTGCTTCACAATTTTCTTATGAA
    TTGCATGATGCTAGTGGTGCAGAAAATTATCTCCTTACTGCAAAAGAAGACGCTGAGGAT
    ACAGAAGAAATCTTGCTTCGTTTAGCCACTATTTATCTGGAGCAGGAGCGTTATGAGGAT
    ATTCTAGACTTGCAGAGTGAGGAGCCAGAAAATCTTTTGACCAAGTGGATGATTGCTCGT
    TCTTATCAAGAAATGGACGATTTGGATACTGCTTATGAGCATTATCAAGAGTTGACAGGA
    GATTTGAAGGACAATCCAGAATTTCTGGAACACTATATCTATCTCTTGCGTGAATTGGGA
    CATTTTGAAGAAGCAAAAGTCCATGCTCACACTTACTTAAAACTGGTTCCAGATGATGTG
    CAAATGCAAGAACTGTTTGAGAGATTGTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1230

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: BMJ42_RS07705 [old locus tag: BMJ42_01456 ]
  • symbol: BMJ42_RS07705
  • description: tetratricopeptide repeat protein
  • length: 409
  • theoretical pI: 3.92786
  • theoretical MW: 47483.3
  • GRAVY: -0.458924

⊟Function[edit | edit source]

  • TIGRFAM:
    putative PEP-CTERM system TPR-repeat lipoprotein (TIGR02917; HMM-score: 60)
    and 7 more
    type IV pilus biogenesis/stability protein PilW (TIGR02521; HMM-score: 43)
    type III secretion low calcium response chaperone LcrH/SycD (TIGR02552; HMM-score: 23.2)
    tol-pal system protein YbgF (TIGR02795; HMM-score: 21.6)
    Unknown function General heme biosynthesis-associated TPR protein (TIGR00540; HMM-score: 19)
    poly-beta-1,6 N-acetyl-D-glucosamine export porin PgaA (TIGR03939; HMM-score: 16)
    FimV C-terminal domain (TIGR03504; HMM-score: 13.1)
    putative peptide modification system cyclase (TIGR04510; HMM-score: 11.4)
  • TheSEED: data available for D39, Hungary19A-6, TIGR4
  • PFAM:
    TPR (CL0020) TPR_2; Tetratricopeptide repeat (PF07719; HMM-score: 63.5)
    TPR_8; Tetratricopeptide repeat (PF13181; HMM-score: 62.9)
    TPR_19; Tetratricopeptide repeat (PF14559; HMM-score: 61.9)
    TPR_1; Tetratricopeptide repeat (PF00515; HMM-score: 56.7)
    and 17 more
    TPR_14; Tetratricopeptide repeat (PF13428; HMM-score: 49.9)
    TPR_12; Tetratricopeptide repeat (PF13424; HMM-score: 38.8)
    TPR_7; Tetratricopeptide repeat (PF13176; HMM-score: 38.1)
    TPR_16; Tetratricopeptide repeat (PF13432; HMM-score: 34.7)
    TPR_21; Tetratricopeptide repeat-like domain (PF09976; HMM-score: 23.4)
    TPR_17; Tetratricopeptide repeat (PF13431; HMM-score: 21.6)
    TPR_6; Tetratricopeptide repeat (PF13174; HMM-score: 21.4)
    ANAPC3; Anaphase-promoting complex, cyclosome, subunit 3 (PF12895; HMM-score: 21.2)
    TPR_4; Tetratricopeptide repeat (PF07721; HMM-score: 20.3)
    TPR_10; Tetratricopeptide repeat (PF13374; HMM-score: 20)
    Fis1_TPR_C; Fis1 C-terminal tetratricopeptide repeat (PF14853; HMM-score: 18.2)
    TPR_9; Tetratricopeptide repeat (PF13371; HMM-score: 14.7)
    PPR; PPR repeat (PF01535; HMM-score: 13.9)
    ANAPC8; Anaphase promoting complex subunit 8 / Cdc23 (PF04049; HMM-score: 13.8)
    Wzy_C_2; Virulence factor membrane-bound polymerase, C-terminal (PF11846; HMM-score: 13.7)
    TPR_11; TPR repeat (PF13414; HMM-score: 11.8)
    SHNi-TPR; SHNi-TPR (PF10516; HMM-score: 7.6)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.9399
    • Cytoplasmic Membrane Score: 0.0228
    • Cell wall & surface Score: 0.0195
    • Extracellular Score: 0.0178
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.002695
    • TAT(Tat/SPI): 0.000247
    • LIPO(Sec/SPII): 0.000444
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_001065947 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MNNSQQMLQALEEQDLTKAEHYFAKALENDSSDLLYELATYLEGIGFYPQAKEIYLKIVEDFPEVHLNLAAIASEDGQIEEAFTYLEEIQADSDWYVSSLALKADLYQLEGLTDVAREKLLEALTYSEDSLLILGLAELDSELENYQAAIQAYAQLDNRSIYEQTGISTYQRIGFAYAQLGKFETATEFLEKALELEYDDLTAFELASLYFDQEEYQKATLYFKQLDTISPDFEGYEYGYSQALHKEHQVQEALRIAKQGLEKNPFETRLLLAASQFSYELHDASGAENYLLTAKEDAEDTEEILLRLATIYLEQERYEDILDLQSEEPENLLTKWMIARSYQEMDDLDTAYEHYQELTGDLKDNPEFLEHYIYLLRELGHFEEAKVHAHTYLKLVPDDVQMQELFERL

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription[edit | edit source]

  • transcription start site:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

Retrieved from "http://pneumowiki.med.uni-greifswald.de/index.php?title=BMJ42_RS07705&oldid=132197"