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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 12-FEB-2025

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae NCTC7466
  • locus tag: DQM66_RS00010 [old locus tag: NCTC7466_00002 ]
  • pan locus tag?: PNEUPAN000169000
  • symbol: dnaN
  • pan gene symbol?: dnaN
  • synonym:
  • product: DNA polymerase III subunit beta

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: DQM66_RS00010 [old locus tag: NCTC7466_00002 ]
  • symbol: dnaN
  • product: DNA polymerase III subunit beta
  • replicon: chromosome
  • strand: +
  • coordinates: 1521..2657
  • length: 1137
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

  • Location: NZ_LS483374 (1521..2657) NCBI
  • BioCyc:
  • MicrobesOnline:
  • PneumoBrowse for strain D39V: SPV_0002 PneumoBrowse

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    ATGATTCATTTTTCAATTAATAAAAATTTATTTCTACAAGCATTAAATATTACTAAGAGA
    GCTATTAGTTCTAAAAATGCCATTCCTATTTTATCAACTGTCAAAATTGACGTGACCAAC
    GAAGGTGTTACTTTAATTGGTTCAAATGGTCAAATTTCAATTGAAAATTTTATTTCTCAA
    AAAAATGAAGATGCTGGTTTGTTAATTACTTCTTTAGGTTCGATCCTTCTTGAAGCTTCT
    TTCTTTATCAATGTAGTATCTAGTTTACCTGATGTAACTCTTGATTTTAAAGAAATTGAA
    CAAAATCAAATTGTTTTAACCAGTGGCAAATCAGAAATTACCCTAAAAGGAAAAGATAGC
    GAACAATATCCACGAATCCAAGAAATTTCAGCAAGCACTCCTTTAATACTTGAAACAAAA
    TTACTCAAGAAAATTATTAATGAAACAGCCTTTGCTGCAAGTACACAAGAGAGTCGTCCG
    ATTTTAACAGGTGTCCACTTCGTATTGAGTCAACACAAAGAGTTAAAAACAGTTGCAACA
    GACTCTCATCGCCTAAGCCAGAAAAAATTAACTCTTGAAAAAAATAGTGATGATTTTGAT
    GTCGTAATTCCTAGCCGTTCTCTACGCGAATTTTCAGCGGTATTTACAGATGATATCGAA
    ACTGTAGAGATTTTCTTTGCCAATAACCAAATCCTCTTTAGAAGCGAAAATATTAGCTTC
    TATACTCGTCTCCTAGAAGGAAACTATCCTGATACAGATCGCTTGATTCCAACAGACTTT
    AACACTACTATTACTTTTAATGTGGTAAACTTACGCCAGTCAATGGAGCGTGCCCGTCTT
    TTATCAAGTGCGACTCAAAATGGTACTGTGAAACTTGAAATTAAGGATGGGGTTGTTAGC
    GCCCATGTTCACTCTCCAGAAGTTGGTAAAGTAAACGAAGAAATCGATACTGATCAGGTT
    ACTGGTGAAGATTTGACCATTAGTTTCAACCCAACTTACTTGATTGATTCTCTTAAAGCT
    TTAAATAGCGAAAAGGTGACCATTAGCTTTATCTCAGCTGTTCGTCCATTTACTCTTGTG
    CCAGCAGATACTGACGAAGACTTCATGCAGCTCATTACACCAGTTCGTACAAATTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1137

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: DQM66_RS00010 [old locus tag: NCTC7466_00002 ]
  • symbol: DnaN
  • description: DNA polymerase III subunit beta
  • length: 378
  • theoretical pI: 4.79238
  • theoretical MW: 42070.4
  • GRAVY: -0.0981481

⊟Function[edit | edit source]

  • reaction:
    EC 2.7.7.7?  ExPASy
    DNA-directed DNA polymerase Deoxynucleoside triphosphate + DNA(n) = diphosphate + DNA(n+1)
  • TIGRFAM:
    Genetic information processing DNA metabolism DNA replication, recombination, and repair DNA polymerase III, beta subunit (TIGR00663; EC 2.7.7.7; HMM-score: 307.8)
  • TheSEED: data available for D39, Hungary19A-6, TIGR4
  • PFAM:
    DNA_clamp (CL0060) DNA_pol3_beta_2; DNA polymerase III beta subunit, central domain (PF02767; HMM-score: 118.3)
    DNA_pol3_beta; DNA polymerase III beta subunit, N-terminal domain (PF00712; HMM-score: 109.9)
    DNA_pol3_beta_3; DNA polymerase III beta subunit, C-terminal domain (PF02768; HMM-score: 106.3)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 9.67
    • Cytoplasmic Membrane Score: 0.01
    • Cellwall Score: 0.15
    • Extracellular Score: 0.17
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.8823
    • Cytoplasmic Membrane Score: 0.0847
    • Cell wall & surface Score: 0.0075
    • Extracellular Score: 0.0256
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.01182
    • TAT(Tat/SPI): 0.000928
    • LIPO(Sec/SPII): 0.001778
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_000581138 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MIHFSINKNLFLQALNITKRAISSKNAIPILSTVKIDVTNEGVTLIGSNGQISIENFISQKNEDAGLLITSLGSILLEASFFINVVSSLPDVTLDFKEIEQNQIVLTSGKSEITLKGKDSEQYPRIQEISASTPLILETKLLKKIINETAFAASTQESRPILTGVHFVLSQHKELKTVATDSHRLSQKKLTLEKNSDDFDVVIPSRSLREFSAVFTDDIETVEIFFANNQILFRSENISFYTRLLEGNYPDTDRLIPTDFNTTITFNVVNLRQSMERARLLSSATQNGTVKLEIKDGVVSAHVHSPEVGKVNEEIDTDQVTGEDLTISFNPTYLIDSLKALNSEKVTISFISAVRPFTLVPADTDEDFMQLITPVRTN

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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