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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 14-DEC-2020

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae NCTC7466
  • locus tag: DQM66_RS09805 [old locus tag: NCTC7466_01882 ]
  • pan locus tag?: PNEUPAN003622000
  • symbol: DQM66_RS09805
  • pan gene symbol?: ulaD
  • synonym:
  • product: 3-keto-L-gulonate-6-phosphate decarboxylase UlaD

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: DQM66_RS09805 [old locus tag: NCTC7466_01882 ]
  • symbol: DQM66_RS09805
  • product: 3-keto-L-gulonate-6-phosphate decarboxylase UlaD
  • replicon: chromosome
  • strand: -
  • coordinates: 1830659..1831324
  • length: 666
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: NZ_LS483374 (1830659..1831324) NCBI
  • BioCyc:
  • MicrobesOnline:
  • PneumoBrowse for strain D39V: SPV_1844 PneumoBrowse

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    ATGACAAAAAGAATACCTAATTTACAAGTTGCATTAGACCATTCAGACTTGCAAGGAGCG
    ATTAAAGCAGCTGTTTCTGTTGGTCAGGAAGTAGATATTATCGAAGCTGGAACTGTTTGC
    TTGCTTCAAGTTGGAAGTGAACTGGCTGAAGTCTTGCGTAGCCTTTTCCCAGATAAGATT
    ATTGTGGCAGACACAAAATGTGCTGATGCTGGTGGAACAGTTGCTAAAAATAATGCGGTT
    CGTGGAGCAGACTGGATGACTTGTATCTGTTGTGCAACCATCCCTACTATGGAAGCAGCT
    CTAAAGGCTATCAAGACTGAACGAGGAGAACGAGGCGAAATCCAGATCGAGCTTTATGGC
    GATTGGACTTTTGAACAAGCTCAGCTTTGGCTAGATGCAGGTATTTCACAAGCTATTTAT
    CACCAATCTCGTGATGCTCTTCTTGCTGGTGAAACTTGGGGTGAAAAAGACCTTAATAAG
    GTTAAAAAACTCATTGACATGGGCTTCCGTGTATCTGTAACAGGTGGTCTAGATGTAGAT
    ACTCTCAAACTCTTTGAAGGTGTTGATGTCTTTACCTTTATCGCAGGTCGTGGAATTACA
    GAGGCTGCGGATCCAGCAGGAGCAGCGCGTGCCTTCAAGGATGAAATCAAACGAATTTGG
    GGGTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    666

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: DQM66_RS09805 [old locus tag: NCTC7466_01882 ]
  • symbol: DQM66_RS09805
  • description: 3-keto-L-gulonate-6-phosphate decarboxylase UlaD
  • length: 221
  • theoretical pI: 4.64266
  • theoretical MW: 23854.2
  • GRAVY: 0.0438914

⊟Function[edit | edit source]

  • TIGRFAM:
    3-hexulose-6-phosphate synthase (TIGR03128; EC 4.1.2.43; HMM-score: 103.1)
    and 3 more
    Metabolism Purines, pyrimidines, nucleosides, and nucleotides Pyrimidine ribonucleotide biosynthesis orotidine 5'-phosphate decarboxylase (TIGR01740; EC 4.1.1.23; HMM-score: 36.7)
    Metabolism Energy metabolism Electron transport NADH-quinone oxidoreductase, B subunit (TIGR01957; HMM-score: 13)
    conserverd hypothetical protein (TIGR02448; HMM-score: 12.1)
  • TheSEED: data available for D39, Hungary19A-6, TIGR4
  • PFAM:
    TIM_barrel (CL0036) OMPdecase; Orotidine 5'-phosphate decarboxylase / HUMPS family (PF00215; HMM-score: 94.4)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.005219
    • TAT(Tat/SPI): 0.00057
    • LIPO(Sec/SPII): 0.000349
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_000166727 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MTKRIPNLQVALDHSDLQGAIKAAVSVGQEVDIIEAGTVCLLQVGSELAEVLRSLFPDKIIVADTKCADAGGTVAKNNAVRGADWMTCICCATIPTMEAALKAIKTERGERGEIQIELYGDWTFEQAQLWLDAGISQAIYHQSRDALLAGETWGEKDLNKVKKLIDMGFRVSVTGGLDVDTLKLFEGVDVFTFIAGRGITEAADPAGAARAFKDEIKRIWG

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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