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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 14-DEC-2020

Summary[edit | edit source]

  • organism: Streptococcus pneumoniae NCTC7466
  • locus tag: DQM66_RS10750 [old locus tag: NCTC7466_02064 ]
  • pan locus tag?: PNEUPAN003912000
  • symbol: raiA
  • pan gene symbol?: hpf
  • synonym:
  • product: ribosome-associated translation inhibitor RaiA

Genome View[edit | edit source]

Gene[edit | edit source]

General[edit | edit source]

  • type: CDS
  • locus tag: DQM66_RS10750 [old locus tag: NCTC7466_02064 ]
  • symbol: raiA
  • product: ribosome-associated translation inhibitor RaiA
  • replicon: chromosome
  • strand: -
  • coordinates: 2012627..2013175
  • length: 549
  • essential: unknown

Accession numbers[edit | edit source]

  • Location: NZ_LS483374 (2012627..2013175) NCBI
  • BioCyc:
  • MicrobesOnline:
  • PneumoBrowse for strain D39V: SPV_2033 PneumoBrowse

Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    ATGATTAAATATAGTATCCGTGGTGAAAACCTAGAAGTAACAGAAGCAATTCGTGATTAT
    GTAGTTTCTAAACTCGAAAAGATCGAAAAGTACTTCCAACCAGAACAAGAGTTGGATGCC
    CGAATTAACTTAAAAGTTTATCGTGAAAAAACGGCTAAAGTGGAAGTAACGATTCCGCTT
    GGATCTATTACTCTCCGCGCAGAAGATGTATCTCAAGATATGTATGGTTCAATTGACCTT
    GTAACTGATAAAATTGAACGTCAGATTCGTAAAAATAAAACAAAAATCGAGCGTAAAAAT
    AAAAATAAGGTAGCAACTGGTCAATTATTTACAGATGCTTTGGTGGAAGATTCAAATATT
    GTCCAGTCTAAAGTTGTTCGTTCAAAACAAATTGATTTAAAACCAATGGATTTGGAAGAA
    GCAATTCTACAAATGGATTTATTGGGGCATGATTTCTTTATCTATGTGGATGTTGAAGAT
    CAGACAACCAATGTGATTTATCGTCGTGAGGATGGCGAAATTGGTTTGTTAGAGGTTAAA
    GAATCTTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    549

Protein[edit | edit source]

General[edit | edit source]

  • locus tag: DQM66_RS10750 [old locus tag: NCTC7466_02064 ]
  • symbol: RaiA
  • description: ribosome-associated translation inhibitor RaiA
  • length: 182
  • theoretical pI: 4.80433
  • theoretical MW: 21099
  • GRAVY: -0.506593

Function[edit | edit source]

  • TIGRFAM:
    Genetic information processing Protein synthesis Translation factors ribosomal subunit interface protein (TIGR00741; HMM-score: 96.7)
    and 2 more
    Metabolism Energy metabolism ATP-proton motive force interconversion Na,H/K antiporter P-type ATPase, alpha subunit (TIGR01106; EC 3.6.3.-; HMM-score: 14.6)
    Genetic information processing Protein synthesis tRNA aminoacylation serine--tRNA ligase (TIGR00414; EC 6.1.1.11; HMM-score: 11.8)
  • TheSEED: data available for D39, Hungary19A-6, TIGR4
  • PFAM:
    RNase_H (CL0219) Ribosomal_S30AE; Sigma 54 modulation protein / S30EA ribosomal protein (PF02482; HMM-score: 92.7)
    no clan defined Ribosom_S30AE_C; Sigma 54 modulation/S30EA ribosomal protein C terminus (PF16321; HMM-score: 86.7)

Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 9.97
    • Cytoplasmic Membrane Score: 0
    • Cellwall Score: 0.01
    • Extracellular Score: 0.02
    • Internal Helices: 0
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.001454
    • TAT(Tat/SPI): 0.001239
    • LIPO(Sec/SPII): 0.000222
  • predicted transmembrane helices (TMHMM): 0

Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_000599104 NCBI
  • UniProt:

Protein sequence[edit | edit source]

  • MIKYSIRGENLEVTEAIRDYVVSKLEKIEKYFQPEQELDARINLKVYREKTAKVEVTIPLGSITLRAEDVSQDMYGSIDLVTDKIERQIRKNKTKIERKNKNKVATGQLFTDALVEDSNIVQSKVVRSKQIDLKPMDLEEAILQMDLLGHDFFIYVDVEDQTTNVIYRREDGEIGLLEVKES

Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

Expression & Regulation[edit | edit source]

Operon[edit | edit source]

Regulation[edit | edit source]

Expression data[edit | edit source]

Biological Material[edit | edit source]

Mutants[edit | edit source]

Expression vector[edit | edit source]

lacZ fusion[edit | edit source]

GFP fusion[edit | edit source]

two-hybrid system[edit | edit source]

FLAG-tag construct[edit | edit source]

Antibody[edit | edit source]

Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

Literature[edit | edit source]

References[edit | edit source]

Relevant publications[edit | edit source]