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PangenomeTIGR4
serotype 4
D39serotype 2
D39Vserotype 2
Hungary19A-6serotype 19A
EF3030serotype 19F
670-6Bserotype 6B
6A-10serotype 6A
70585serotype 5
A026serotype 19F
A66serotype 3
AP200serotype 11A
ASP0581serotype 12F
ATCC 49619serotype 19F
ATCC 700669serotype 23F
BVJ1JLserotype 1
CGSP14serotype 14
G54serotype 19F
HU-OHserotype 3
Hu15serotype 19A
Hu17serotype 19A
INV104serotype 1
INV200serotype 14
JJAserotype 14
MDRSPN001serotype 19F
NCTC7466serotype 2
NU83127serotype 4
OXC141serotype 3
P1031serotype 1
R6serotype 2
SP49serotype 19A
SPN032672serotype 1
SPN034156serotype 3
SPN034183serotype 3
SPN994038serotype 3
SPN994039serotype 3
SPNA45serotype 3
ST556serotype 19F
TCH8431/19Aserotype 19A
Taiwan19F-14serotype 19F
Xen35serotype 4
gamPNI0373serotype 1
NCBI: 16-MAY-2019
⊟Summary[edit | edit source]
- organism: Streptococcus pneumoniae EF3030
- locus tag: EF3030_00420 [new locus tag: EF3030_RS00420 ]
- pan locus tag?: PNEUPAN000734000
- symbol: pavB
- pan gene symbol?: pavB
- synonym:
- product: fibronectin-binding SSURE repeat adhesin PavB
⊟Genome View[edit | edit source]
⊟Gene[edit | edit source]
⊟General[edit | edit source]
- type: CDS, pseudogene
- locus tag: EF3030_00420 [new locus tag: EF3030_RS00420 ]
- symbol: pavB
- product: fibronectin-binding SSURE repeat adhesin PavB
- replicon: chromosome
- strand: +
- coordinates: 80531..83561
- length: 3031
- essential: unknown
⊟Accession numbers[edit | edit source]
- Location: CP035897 (80531..83561) NCBI
- BioCyc: see EF3030_RS00420
- MicrobesOnline:
- PneumoBrowse for strain D39V: SPV_0080 PneumoBrowse
⊟Phenotype[edit | edit source]
Share your knowledge and add information here. [edit]
⊟DNA sequence[edit | edit source]
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3001ATGAAATTCAATCCAAATCAAAGATATACTCGTTGGTCTATTCGCCGTCTCAGTGTCGGT
GTTGCCTCAGTTGTTGTGGCTAGTGGCTTCTTTGTCCTAGTTGGTCAGCCAAGTTCTGTA
CGTGCCGATGGGCTCAATCCAACCCCAGGTCAAGTCTTACCTGAAGAGACATCGGGAACG
AAAGAGGGTGACTTATCAGAAAAACCAGGAGACACCGTTCTCACTCAAGCGAAACCTGAG
GGCGTTACTGGAAATACGAATTCACTTCCGACACCTACAGAAAGAACTGAAGTGAGCGAG
GAAACAAGCCCTTCTAGTCTGGATACACTTTTTGAAAAAGATGAAGAAGCTCAAAAAAAT
CCAGAGCTAACAGATGTCTTAAAAGAAACTGTAGATACAGCTGATGTGGATGGGACACAA
GCAAGTCCAGCAGAAACTACTCCTGAACAAGTAAAAGGTGGAGTGAAAGAAAATACAAAA
GACAGCATCGATGTTCCTGCTGCTTATCTTGAAAAAGCTGAAGGGAAAGGTCCTTTCACT
GCCGGTGTAAACCAAGTAATTCCTTATGAACTATTCGCTGGTGATGGTATGTTAACTCGT
CTATTACTAAAAGCTTCGGATAATGCTCCTTGGTCTGACAATGGTACTGCTAAAAATCCT
GCTTTACCTCCTCTTGAAGGATTAACAAAAGGGAAATACTTCTATGAAGTAGACTTAAAT
GGCAATACTGTTGGTAAACAAGGTCAAGCTTTAATTGATCAACTTCGCGCTAATGGTACT
CAAACTTATAAAGCTACTGTTAAAGTTTACGGAAATAAAGACGGTAAAGCTGACTTGACT
AATCTAGTTGCTACTAAAAATGTAGACATCAACATCAATGGATTAGTTGCTAAAGAAACG
GTTCAAAAAGCCGTTGCAGACAACGTTAAAGACAGTATCGATGTTCCAGCAGCCTACCTA
GAAAAAGCCAAGGGTGAAGGTCCATTCACAGCAGGTGTCAACCATGTGATTCCATACGAA
CTCTTCGCAGGTGATGGCATGTTGACTCGTCTCTTGCTCAAGGCATCTGACAAGGCACCA
TGGTCAGATAACGGCGACGCTAAAAACCCAGTCCTATCTCCACTAGGCGAAAACGTGAAG
ACCAAAGGTCAATACTTCTATCAAGTAGCCTTGGACGGAAATGTAGCTGGCAAAGAAAAA
CAAGCGCTCATTGACCAGTTCCGAGCAAATGGTACTCAAACTTACAGCGCTACAGTCAAT
GTCTATGGTAACAAAGACGGTAAACCAGACTTGGACAACATCGTAGCAACTAAAAAAGTC
ACTATTAACATAAACGGTTTAATTTCTAAAGAAACAGTTCAAAAAGCCGTTGCAGACAAC
GTTAAGGACAGTATCGATGTTCCAGCAGCCTACCTAGAAAAGGCCAAGGGTGAAGGTCCA
TTCACAGCAGGTGTCAACCATGTGATTCCATACGAACTCTTCGCAGGTGATGGTATGTTG
ACTCGTCTCTTGCTCAAGGCATCTGACAAGGCACCATGGTCAGATAACGGCGACGCTAAA
AACCCAGCCCTATCTCCACTAGGTGAAAACGTGAAGACCAAAGGTCAATACTTCTATCAA
GTAGCCTTGGACGGAAATGTAGCTGGCAAAGAAAAAACAAGCGCTCATTGACCAGTTCCG
AGCAAATGGTACTCAAACTTACAGCGCTACAGTCAATGTCTATGGTAACAAAGACGGTAA
ACCAGACTTGGACAACATCGTAGCAACTAAAAAAGTCACTATTAACATAAACGGTTTAAT
TTCTAAAGAAACAGTTCAAAAAGCCGTTGCAGACAACGTTAAGGACAGTATCGATGTTCC
AGCAGCCTACCTAGAAAAGGCCAAGGGTGAAGGTCCATTCACAGCAGGTGTCAACCATGT
GATTCCATACGAACTCTTCGCAGGTGATGGTATGTTGACTCGTCTCTTGCTCAAGGCATC
TGACAAGGCACCATGGTCAGATAACGGTGACGCTAAAAACCCAGCCCTATCTCCACTAGG
TGAAAACGTGAAGACCAAAGGTCAATACTTCTATCAATTAGCCTTGGACGGAAATGTAGC
TGGCAAAGAAAAACAAGCGCTCATTGACCAGTTCCGAGCAAATGGTACTCAAACTTACAG
CGCTACAGTCAATGTCTATGGTAACAAAGACGGTAAACCAGACTTGGACAACATCGTAGC
AACTAAAAAAGTCACTATTAACATAAACGGTTTAATTTCTAAAGAAACAGTTCAAAAAGC
CGTTGCAGACAACGTTAAGGACAGTATCGATGTTCCAGCAGCCTACCTAGAAAAGGCCAA
GGGTGAAGGTCCATTCACAGCAGGTGTCAACCATGTGATTCCATACGAACTCTTCGCAGG
TGATGGTATGTTGACTCGTCTCTTGCTCAAGGCATCTGACAAGGCACCATGGTCAGATAA
CGGCGACGCTAAAAACCCAGCTCTATCTCCACTAGGTGAAAACGTGAAGACCAAAGGTCA
ATACTTCTATCAAGTAGCCTTGGACGGAAATGTAGCTGGCAAAGAAAAACAAGCGCTCAT
TGACCAGTTCCGAGCAAACGGTACTCAAACTTACAGCGCTACAGTCAATGTCTATGGTAA
CAAAGACGGTAAACCAGACTTGGACAACATCGTAGCAACTAAAAAAGTCACTATTAAGAT
AAATGTTAAAGAAACATCAGACACAGCAAATGGTTCATTATCACCTTCTAACTCTGGTTC
TGGCGTGACTCCGATGAATCACAATCATGCTACAGGTACTACAGATAGCATGCCTGCTGA
CACCATGACAAGTTCTACCAACACGATGGCAGGTGAAAACATGGCTGCTTCTGCTAACAA
GATGTCTGATACGATGATGTCAGAGGATAAAGCTATGCTACCAAATACTGGTGAGACTCA
AACATCAATGGCAAGTATTGGTTTCCTTGGGCTTGCGCTTGCAGGTTTACTCGGTGGTCT
AGGTTTGAAAAACAAAAAAGAAGAAAACTAA60
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⊟Protein[edit | edit source]
⊟General[edit | edit source]
- locus tag: EF3030_00420 [new locus tag: EF3030_RS00420 ]
- symbol: PavB
- description: fibronectin-binding SSURE repeat adhesin PavB
- length:
- theoretical pI:
- theoretical MW:
- GRAVY:
⊟Function[edit | edit source]
- TIGRFAM:
- TheSEED: data available for D39, Hungary19A-6, TIGR4
- PFAM:
⊟Structure, modifications & cofactors[edit | edit source]
- domains:
- modifications:
- cofactors:
- effectors:
⊟Localization[edit | edit source]
- PSORTb:
- SignalP:
- predicted transmembrane helices (TMHMM):
⊟Accession numbers[edit | edit source]
- GI:
- RefSeq:
- UniProt:
⊟Protein sequence[edit | edit source]
⊟Experimental data[edit | edit source]
- protein localization:
- interaction partners:
⊟Expression & Regulation[edit | edit source]
⊟Operon[edit | edit source]
⊟Regulation[edit | edit source]
- regulator:
⊟Expression data[edit | edit source]
- PneumoExpress for strain D39V: SPV_0080 PneumoExpress
⊟Biological Material[edit | edit source]
⊟Mutants[edit | edit source]
⊟Expression vector[edit | edit source]
⊟lacZ fusion[edit | edit source]
⊟GFP fusion[edit | edit source]
⊟two-hybrid system[edit | edit source]
⊟FLAG-tag construct[edit | edit source]
⊟Antibody[edit | edit source]
⊟Other Information[edit | edit source]
You are kindly invited to share additional interesting facts.
⊟Literature[edit | edit source]
⊟References[edit | edit source]
⊟Relevant publications[edit | edit source]
Inga Jensch, Gustavo Gámez, Michael Rothe, Sandra Ebert, Marcus Fulde, Daniela Somplatzki, Simone Bergmann, Lothar Petruschka, Manfred Rohde, Roland Nau, Sven Hammerschmidt
PavB is a surface-exposed adhesin of Streptococcus pneumoniae contributing to nasopharyngeal colonization and airways infections.
Mol Microbiol: 2010, 77(1);22-43
[PubMed:20444103] [WorldCat.org] [DOI] (I p)Ulrike Binsker, Thomas P Kohler, Krystin Krauel, Sylvia Kohler, Hansjörg Schwertz, Sven Hammerschmidt
Pneumococcal Adhesins PavB and PspC Are Important for the Interplay with Human Thrombospondin-1.
J Biol Chem: 2015, 290(23);14542-55
[PubMed:25897078] [WorldCat.org] [DOI] (I p)Sajida Kanwal, Inga Jensch, Gottfried J Palm, Mark Brönstrup, Manfred Rohde, Thomas P Kohler, Daniela Somplatzki, Werner Tegge, Howard F Jenkinson, Sven Hammerschmidt
Mapping the recognition domains of pneumococcal fibronectin-binding proteins PavA and PavB demonstrates a common pattern of molecular interactions with fibronectin type III repeats.
Mol Microbiol: 2017, 105(6);839-859
[PubMed:28657670] [WorldCat.org] [DOI] (I p)