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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 16-MAY-2019

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae EF3030
  • locus tag: EF3030_01255 [new locus tag: EF3030_RS01255 ]
  • pan locus tag?: PNEUPAN000983000
  • symbol: EF3030_01255
  • pan gene symbol?: PTS-EIIC_2
  • synonym:
  • product: PTS sugar transporter subunit IIC

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: EF3030_01255 [new locus tag: EF3030_RS01255 ]
  • symbol: EF3030_01255
  • product: PTS sugar transporter subunit IIC
  • replicon: chromosome
  • strand: +
  • coordinates: 217257..218579
  • length: 1323
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    GTGGGTAAGAAAAGGAGATTTATTATGTCAAAGATGGATGTTCAGAAAATCATTGCACCG
    ATGATGAAGTTTGTGAATATGCGTGGCATTATAGCTCTAAAAGATGGGATGTTAGCAATT
    TTGCCATTGACAGTAGTTGGTAGTTTATTCTTGATTATGGGACAATTGCCGTTCGAAGGA
    TTAAATAAGAGCATTGCTAGTGTTTTTGGAGCTAATTGGACAGAGCCGTTTATGCAAGTA
    TATTCAGGAACTTTTGCTATTATGGGTCTAATTTCTTGTTTTTCAATTGCCTATTCTTAT
    GCTAAGAATAGCGGAGTAGAGGCTTTACCAGCTGGAGTTCTATCTGTATCTGCATTCTTT
    ATTTTGCTAAGATCATCTTATATCCCTAAACAAGGTGAGGCGATTGGGGACGCTATTAGT
    AAAGTTTGGTTTGGAGGCCAAGGAATTATCGGTGCTATCATTATAGGTTTGGTAGTAGGA
    AGTATTTATACCTTCTTTATAAAGAGAAAAATTGTTATTAAGATGCCAGAACAAGTTCCA
    CAAGCTATTGCCAAACAGTTTGAAGCAATGATTCCAGCATTTGTAATTTTCTTATCTTCT
    ATGATTGTATATATTTTAGCGAAGTCATTGACTAATGGCGGAACATTCATAGAAATGATT
    TATTCTGCTATTCAAGTTCCGTTGCAAGGTTTAACTGGATCTTTGTATGGTGCTATTGGA
    ATTGCATTCTTTATATCATTTTTGTGGTGGTTTGGTGTTCATGGGCAATCGGTAGTAAAT
    GGAGTAGTGACAGCTCTGCTTTTATCTAATCTTGACGCTAATAAAACTATGTTAGCCTCT
    GCTAATCTATCATTAGAAAATGGTGCACATATTGTTACTCAACAATTTTTAGATTCATTT
    TTAATTCTATCAGGTTCAGGGATTACGTTTGGTCTTGTAGTTGCCATGCTTTTTGCAGCA
    AAATCAAAACAATACCAAGCCTTAGGAAAAGTTGCAGCTTTTCCAGCAATATTTAACGTA
    AATGAGCCAGTTGTATTTGGATTTCCGATTGTCATGAATCCAGTTATGTTTGTACCTTTC
    ATTCTTGTTCCTGTACTTGCAGCTGTGATAGTATATGGAGCTATTGCAACAGGTTTCATG
    CAGCCATTCTCAGGGGTAACATTGCCTTGGAGTACACCAGCTATTCTATCAGGATTTTTG
    GTGGGTGGATGGCAAGGTGTTGTGACTCAGTTATTAGTATTGGTGATATCTACAGTGGTT
    TACTTTCCATTCTTTAAGATACAAGATCGTTTAGCTTACCAAAATGAAATCAAACAATCT
    TAG
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1323

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: EF3030_01255 [new locus tag: EF3030_RS01255 ]
  • symbol: EF3030_01255
  • description: PTS sugar transporter subunit IIC
  • length: 440
  • theoretical pI: 10.0661
  • theoretical MW: 47556.5
  • GRAVY: 0.846136

⊟Function[edit | edit source]

  • TIGRFAM:
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids PTS system, cellobiose-specific IIC component (TIGR00359; EC 2.7.1.69; HMM-score: 385.6)
    Signal transduction Signal transduction PTS PTS system, cellobiose-specific IIC component (TIGR00359; EC 2.7.1.69; HMM-score: 385.6)
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids PTS system, lactose/cellobiose family IIC component (TIGR00410; EC 2.7.1.69; HMM-score: 385.6)
    Signal transduction Signal transduction PTS PTS system, lactose/cellobiose family IIC component (TIGR00410; EC 2.7.1.69; HMM-score: 385.6)
    and 2 more
    Metabolism Transport and binding proteins Carbohydrates, organic alcohols, and acids PTS system, lactose-specific IIC component (TIGR00394; EC 2.7.1.69; HMM-score: 188.1)
    Signal transduction Signal transduction PTS PTS system, lactose-specific IIC component (TIGR00394; EC 2.7.1.69; HMM-score: 188.1)
  • TheSEED: data available for D39, Hungary19A-6, TIGR4
  • PFAM:
    PTS_EIIC (CL0493) PTS_EIIC; Phosphotransferase system, EIIC (PF02378; HMM-score: 223.1)
    and 2 more
    no clan defined UPF0154; Uncharacterised protein family (UPF0154) (PF03672; HMM-score: 12.3)
    DUF3311; Protein of unknown function (DUF3311) (PF11755; HMM-score: 6.4)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 10
    • Cellwall Score: 0
    • Extracellular Score: 0
    • Internal Helices: 10
  • DeepLocPro: Cytoplasmic Membrane
    • Cytoplasmic Score: 0
    • Cytoplasmic Membrane Score: 0.9988
    • Cell wall & surface Score: 0
    • Extracellular Score: 0.0012
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.00645
    • TAT(Tat/SPI): 0.00035
    • LIPO(Sec/SPII): 0.000967
  • predicted transmembrane helices (TMHMM): 10

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: QBF68277 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MGKKRRFIMSKMDVQKIIAPMMKFVNMRGIIALKDGMLAILPLTVVGSLFLIMGQLPFEGLNKSIASVFGANWTEPFMQVYSGTFAIMGLISCFSIAYSYAKNSGVEALPAGVLSVSAFFILLRSSYIPKQGEAIGDAISKVWFGGQGIIGAIIIGLVVGSIYTFFIKRKIVIKMPEQVPQAIAKQFEAMIPAFVIFLSSMIVYILAKSLTNGGTFIEMIYSAIQVPLQGLTGSLYGAIGIAFFISFLWWFGVHGQSVVNGVVTALLLSNLDANKTMLASANLSLENGAHIVTQQFLDSFLILSGSGITFGLVVAMLFAAKSKQYQALGKVAAFPAIFNVNEPVVFGFPIVMNPVMFVPFILVPVLAAVIVYGAIATGFMQPFSGVTLPWSTPAILSGFLVGGWQGVVTQLLVLVISTVVYFPFFKIQDRLAYQNEIKQS

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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