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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 30-NOV-2024

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae EF3030
  • locus tag: EF3030_RS08230 [old locus tag: EF3030_08230 ]
  • pan locus tag?: PNEUPAN003172000
  • symbol: EF3030_RS08230
  • pan gene symbol?: tmcAL
  • synonym:
  • product: nucleotidyltransferase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: EF3030_RS08230 [old locus tag: EF3030_08230 ]
  • symbol: EF3030_RS08230
  • product: nucleotidyltransferase
  • replicon: chromosome
  • strand: -
  • coordinates: 1573286..1574383
  • length: 1098
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: NZ_CP035897 (1573286..1574383) NCBI
  • BioCyc: EF3030_RS08230 BioCyc
  • MicrobesOnline:
  • PneumoBrowse for strain D39V: SPV_1552 PneumoBrowse

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    ATGACCATCACGGGTATTATCGCGGAGTTCAATCCTTTTCATAATGGCCATAAATACCTG
    CTGGATCAGGCAGAGGGACTGAAAATTGTTGCCATGTCAGGGAATTTCATGCAGCGTGGA
    GAGCCTGCTATTGTGGATAAGTGGACAAGGGCCCAGATGGCGCTGGAAAATGGCGCAGAC
    TTGGTAGTGGAATTGCCCTTTTTAGTCAGTGTTCAGGCAGCTGATTTCTTTGGTCAAGGA
    GCTGTGGATATCTTGGATCGCTTGGGCATTGATAGTCTAGTTTTTGGGACAGAGGAAGTT
    CTGGATTACCAGAAAATCGCTGACTTATACACAGAGAAAGGTGCTGAGATGGAGAAATTT
    GTGAAAAATCTGCCTGATTCCCTTTCCTATCCCCAGAAAACCCAAGCTATGTGGAAGGAA
    TTTGCTGGTCTTGATTTTTCAGGTAATACCCCCAATCATGTTCTTGCTCTGGCCTATGCC
    AAGGCGGTTGCAGGACGAAATATCAAGCTGCATCCGATTCAGCGTCAGGGGGCAGGTTAC
    CATTCTGTGAATAAAGATGTGGACTTTGCCTCGGCGACAGCCCTCCGTCAACATCAGAAG
    GACCAAGATTTCTTAGAACGTTTTATGCCTTCTGTTGCCCTATTTGAGCAGGCCAGTAAG
    GTGATCTGGGAAGACTATTTTCCCTTGCTCCGCTATCAAATCTTGTCAAATCCCGACCTA
    ACCACCATCTATCAGGTCAATCAAGAAATGGCTGTGCGCATTAAAGAAGCTATTAAAACA
    GCCCAGTCTGTGGAAGAATTGGTCGAGTTAGTGACTACCAAACGTTACACCAAGGCGCGT
    GTCAGACGCCTATTGACCTATATTTTGATGCAGGCTAGAGAAAGTGACTTGCCAGAAGCC
    ATTCATGTCCTTGGATTTACTGAAAAAGGTAGGCAACATCTCAAGTCTTTGAAAGGTCAG
    GTCAGTCTAGTCAGCCGAATTGGCAAAGAACCTTGGGATGCTATGACCCAAAAAGCAGAC
    CAGATTTACCAACTAGGGAAGCCAAGTATAGCAGAGCAAAATTTTGGAAGAGTGCCGATT
    AGAATAGAAACAAACTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1098

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: EF3030_RS08230 [old locus tag: EF3030_08230 ]
  • symbol: EF3030_RS08230
  • description: nucleotidyltransferase
  • length: 365
  • theoretical pI: 6.73729
  • theoretical MW: 41207.9
  • GRAVY: -0.258904

⊟Function[edit | edit source]

  • TIGRFAM:
    cytidyltransferase-like domain (TIGR00125; HMM-score: 19.7)
    and 2 more
    Genetic information processing Protein fate Protein modification and repair [citrate (pro-3S)-lyase] ligase (TIGR00124; EC 6.2.1.22; HMM-score: 13.1)
    Metabolism Energy metabolism Fermentation [citrate (pro-3S)-lyase] ligase (TIGR00124; EC 6.2.1.22; HMM-score: 13.1)
  • TheSEED: data available for D39, Hungary19A-6, TIGR4
  • PFAM:
    HUP (CL0039) HIGH_NTase1; HIGH Nucleotidyl Transferase (PF05636; HMM-score: 366.3)
    and 3 more
    CTP_transf_like; Cytidylyltransferase-like (PF01467; HMM-score: 18.4)
    Citrate_ly_lig; Citrate lyase ligase C-terminal domain (PF08218; HMM-score: 17.7)
    no clan defined E3_UbLigase_R4; E3 ubiquitin-protein ligase UBR4 (PF13764; HMM-score: 10.5)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.9998
    • Cytoplasmic Membrane Score: 0.0001
    • Cell wall & surface Score: 0
    • Extracellular Score: 0.0001
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.002724
    • TAT(Tat/SPI): 0.000276
    • LIPO(Sec/SPII): 0.000305
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_000156330 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MTITGIIAEFNPFHNGHKYLLDQAEGLKIVAMSGNFMQRGEPAIVDKWTRAQMALENGADLVVELPFLVSVQAADFFGQGAVDILDRLGIDSLVFGTEEVLDYQKIADLYTEKGAEMEKFVKNLPDSLSYPQKTQAMWKEFAGLDFSGNTPNHVLALAYAKAVAGRNIKLHPIQRQGAGYHSVNKDVDFASATALRQHQKDQDFLERFMPSVALFEQASKVIWEDYFPLLRYQILSNPDLTTIYQVNQEMAVRIKEAIKTAQSVEELVELVTTKRYTKARVRRLLTYILMQARESDLPEAIHVLGFTEKGRQHLKSLKGQVSLVSRIGKEPWDAMTQKADQIYQLGKPSIAEQNFGRVPIRIETN

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription[edit | edit source]

  • transcription start site:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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