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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 12-FEB-2025

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae ATCC 49619
  • locus tag: EL263_RS06540 [old locus tag: SPAT_1242 ]
  • pan locus tag?: PNEUPAN000141000
  • symbol: EL263_RS06540
  • pan gene symbol?: lanL
  • synonym:
  • product: protein kinase domain-containing protein

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: EL263_RS06540 [old locus tag: SPAT_1242 ]
  • symbol: EL263_RS06540
  • product: protein kinase domain-containing protein
  • replicon: chromosome
  • strand: -
  • coordinates: 1241385..1242788
  • length: 1404
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: NZ_AP018938 (1241385..1242788) NCBI
  • BioCyc: EL263_RS06540 BioCyc
  • MicrobesOnline:
  • PneumoBrowse for strain D39V: SPV_1179 PneumoBrowse

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    1201
    1261
    1321
    1381
    ATGAATAATGATGAGTGGGTTTATCAATACCCTATTGGAAAATTTGTTGAAAGACAAGGG
    TGGAAAATACACATTAGTTCAGAGTATAATAGTTCACACGAATTGTTACAAGATGTAGCA
    AAAATTTGCCATGAAATGCGAATTCCATTTAAACATCTTAGTACAGAAGACAAATTTATC
    ATGCGAAACGGGAAATTGGTTAGTCGAGGATTTTCTGGTAAATTTATTACATGTTATCCA
    AATCAAAATGAATTAGAGTCGGTTTTGCAAAGGTTAGAAAGTGCCTTAAAGCAATATAAT
    GGGCCATATATTTTAAGCGATAAACGTTGGGATGAAGCACCAATATATCTGAGGTATGGT
    GTGTTTAGGCCGTCAAGGGATGATGAAAAGAAGGTTGTTATTGATGAATTAATTGTTGGC
    GATGAAGTTGTTAAAGATGAACGTTTACCAGTATTTAAAATTCCAAAAGGTATAGTGCCC
    CCTGACTTTTTGAATAAATGGCTTGACAAGAAAGATAAAAAACAGGGAGACTTTCCCTTT
    ATTATAGATAATGCAATTAGATTTTCAAACAGTGGTGGGATATATAATGCTAGACTAAAA
    GAAGATGGGAAAAAAATAATTTTAAAAGAGGCTAGACCGTATACAGGTCTAGGATTTGAT
    GGTACTTATTCTTCAGAGAGATTAGCTTCGGAGTGCAAAGCACTAAAAATTCTAAATGAA
    TGGAGTGAGACGCCTAAAATATACTGGCACGGTAAGATCTGGGAGCACACCTTCTTAGGA
    ATTGAACATATGAAGGGCGTTCCACTAAATAGATGGGTTACCAATAATTTTCCTTTATAT
    GAAGTTGTTGATAAGACCAAAGATTATCTATTGAGAGTTTCAAAGATAGTAGAAAAACTC
    ATCGATTTAACGAATAAGTTTCATTCTGAAAATGTATATCATCAAGATTTACATTTAGGA
    AATATCTTGGTTAAGGATGAAGATGAGATTAGTATAATAGACTGGGAACAGGCTGTCTTT
    TCAAATGATGAAAAAGTTGTACATAAAGTTGCAGCCCCTGGTTTTAGAGCATGGCGAGAA
    ACACTTCCCAGTGAGATAGATTGGTATGGTATTAGACAAATAGCTCATTATTTATACATG
    CCACTAGTAACTACATCGGATTTGACATACAACTATGTAAGTCAAACCAGGATAGAAGGA
    AAAAAACTATTTGAGTCTTTGGGTTATACAAGAGAACATATAGATTATGTAGAAAGTTTA
    TTGTCATATCTAGATTCTAAATGTCCACAGATTGAGAATATTTCCAGGAAAAAAGTTTTA
    AAACCCATGCATGAGATTAGAACTATCGAGAGTGAGCAAGATATACAAGATTTTATTATA
    AAAGCTTTTCTTTTAGTGAACTGA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1080
    1140
    1200
    1260
    1320
    1380
    1404

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: EL263_RS06540 [old locus tag: SPAT_1242 ]
  • symbol: EL263_RS06540
  • description: protein kinase domain-containing protein
  • length: 467
  • theoretical pI: 6.89182
  • theoretical MW: 54796.3
  • GRAVY: -0.494433

⊟Function[edit | edit source]

  • TIGRFAM:
    Unknown function General Kae1-associated kinase Bud32 (TIGR03724; EC 2.7.-.-; HMM-score: 29.5)
    and 2 more
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Menaquinone and ubiquinone 2-polyprenylphenol 6-hydroxylase (TIGR01982; EC 1.14.13.-; HMM-score: 18.8)
    Metabolism Biosynthesis of cofactors, prosthetic groups, and carriers Thiamine thiamine kinase (TIGR02721; EC 2.7.1.89; HMM-score: 14)
  • TheSEED: data available for D39, Hungary19A-6, TIGR4
  • PFAM:
    PKinase (CL0016) Pkinase; Protein kinase domain (PF00069; HMM-score: 33)
    ABC1; ABC1 atypical kinase-like domain (PF03109; HMM-score: 27.1)
    and 8 more
    APH; Phosphotransferase enzyme family (PF01636; HMM-score: 25.4)
    RIO1; RIO1 family (PF01163; HMM-score: 21.6)
    Kdo; Lipopolysaccharide kinase (Kdo/WaaP) family (PF06293; HMM-score: 21.6)
    Choline_kinase; Choline/ethanolamine kinase (PF01633; HMM-score: 19.1)
    Haspin_kinase; Haspin like kinase domain (PF12330; HMM-score: 18.6)
    TCAD9; Ternary complex associated domain 9 (PF19974; HMM-score: 15.5)
    OB (CL0021) OB_Dis3; Dis3-like cold-shock domain 2 (CSD2) (PF17849; HMM-score: 12.9)
    PKinase (CL0016) PK_Tyr_Ser-Thr; Protein tyrosine and serine/threonine kinase (PF07714; HMM-score: 11.4)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.7778
    • Cytoplasmic Membrane Score: 0.1776
    • Cell wall & surface Score: 0.0005
    • Extracellular Score: 0.0441
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.005085
    • TAT(Tat/SPI): 0.0002
    • LIPO(Sec/SPII): 0.000586
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_001058022 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MNNDEWVYQYPIGKFVERQGWKIHISSEYNSSHELLQDVAKICHEMRIPFKHLSTEDKFIMRNGKLVSRGFSGKFITCYPNQNELESVLQRLESALKQYNGPYILSDKRWDEAPIYLRYGVFRPSRDDEKKVVIDELIVGDEVVKDERLPVFKIPKGIVPPDFLNKWLDKKDKKQGDFPFIIDNAIRFSNSGGIYNARLKEDGKKIILKEARPYTGLGFDGTYSSERLASECKALKILNEWSETPKIYWHGKIWEHTFLGIEHMKGVPLNRWVTNNFPLYEVVDKTKDYLLRVSKIVEKLIDLTNKFHSENVYHQDLHLGNILVKDEDEISIIDWEQAVFSNDEKVVHKVAAPGFRAWRETLPSEIDWYGIRQIAHYLYMPLVTTSDLTYNYVSQTRIEGKKLFESLGYTREHIDYVESLLSYLDSKCPQIENISRKKVLKPMHEIRTIESEQDIQDFIIKAFLLVN

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription[edit | edit source]

  • transcription start site:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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