From PneumoWiki
Jump to navigation Jump to search
PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 14-DEC-2020

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae ATCC 49619
  • locus tag: EL263_RS10770 [old locus tag: SPAT_2039 ]
  • pan locus tag?: PNEUPAN003829000
  • symbol: argF
  • pan gene symbol?: arcB
  • synonym:
  • product: ornithine carbamoyltransferase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: EL263_RS10770 [old locus tag: SPAT_2039 ]
  • symbol: argF
  • product: ornithine carbamoyltransferase
  • replicon: chromosome
  • strand: +
  • coordinates: 1995458..1996474
  • length: 1017
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: NZ_AP018938 (1995458..1996474) NCBI
  • BioCyc: EL263_RS10770 BioCyc
  • MicrobesOnline:
  • PneumoBrowse for strain D39V: SPV_1976 PneumoBrowse

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    ATGACAAATTCAGTATTCCAAGGACGCAGCTTCTTAGCAGAAAAAGACTTTACCCGTGCA
    GAGTTAGAATACCTTATTGGTCTTTCAGCTCACTTGAAAGATTTGAAAAAACGCAATATT
    CAACACCACTACCTTGCTGGCAAGAATATCGCTCTCCTATTTGAAAAAACATCTACTCGT
    ACTCGTGCAGCCTTTACAACTGCGGCTATCGACCTTGGTGCTCACCCAGAATACCTCGGA
    GCAAATGATATTCAGTTGGGTAAAAAAGAATCTACTGAAGATACTGCTAAAGTATTGGGA
    CGTATGTTTGACGGGATTGAATTCCGCGGATTCAGCCAACGTATGGTTGAAGAATTGGCA
    GAATTCTCAGGCGTTCCAGTATGGAACGGTCTAACTGACGAATGGCACCCAACTCAAATG
    CTCGCTGACTACTTGACTGTTCAAGAAAACTTCGGTCGCTTGGAAGGCTTGACATTGGTA
    TACTGTGGTGATGGACGTAACAACGTTGCCAACAGCTTGCTCGTAACAGGTGCTATCCTT
    GGTGTCAATGTTCACATCTTCTCACCAAAAGAACTCTTCCCAGAAAAAGAAATCGTTGAA
    TTGGCAGAAGGATTTGCTAAAGAAAGTGGCGCACATGTTCTCATCACTGAAGATGCTGAT
    GAAGCAGTTAAAGATGCAGACGTTCTTTACACAGACGTTTGGGTATCAATGGGTGAAGAA
    GACAAATTCGCAGAACGTGTAGCTCTTCTTAAACCTTACCAAGTCAATATGGACTTAGTT
    AAAAAAGCAGGCAATGAAAACTTGATCTTCCTACACTGCTTGCCAGCATTCCACGATACT
    CACACTGTTTATGGTAAAGACGTTGCTGAAAAATTTGGTGTAGAAGAAATGGAAGTAACA
    GACGAAGTCTTCCGCAGCAAGTACGCTCGCCACTTCGATCAAGCAGAAAACCGTATGCAC
    ACTATCAAAGCTGTTATGGCTGCTACACTTGGTAACCTTTATATTCCTAAAGTATAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1017

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: EL263_RS10770 [old locus tag: SPAT_2039 ]
  • symbol: ArgF
  • description: ornithine carbamoyltransferase
  • length: 338
  • theoretical pI: 5.06657
  • theoretical MW: 37910.8
  • GRAVY: -0.219822

⊟Function[edit | edit source]

  • reaction:
    EC 2.1.3.3?  ExPASy
    Ornithine carbamoyltransferase Carbamoyl phosphate + L-ornithine = phosphate + L-citrulline
  • TIGRFAM:
    Metabolism Amino acid biosynthesis Glutamate family ornithine carbamoyltransferase (TIGR00658; EC 2.1.3.3; HMM-score: 410.9)
    and 3 more
    Metabolism Energy metabolism Amino acids and amines putrescine carbamoyltransferase (TIGR04384; EC 2.1.3.6; HMM-score: 259)
    Metabolism Purines, pyrimidines, nucleosides, and nucleotides Pyrimidine ribonucleotide biosynthesis aspartate carbamoyltransferase (TIGR00670; EC 2.1.3.2; HMM-score: 127.4)
    knotted carbamoyltransferase YgeW (TIGR03316; EC 2.1.3.-; HMM-score: 68.6)
  • TheSEED: data available for D39, Hungary19A-6, TIGR4
  • PFAM:
    Asp-glut_race (CL0399) OTCace; Aspartate/ornithine carbamoyltransferase, Asp/Orn binding domain (PF00185; HMM-score: 190.1)
    and 1 more
    no clan defined OTCace_N; Aspartate/ornithine carbamoyltransferase, carbamoyl-P binding domain (PF02729; HMM-score: 151.3)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 9.97
    • Cytoplasmic Membrane Score: 0
    • Cellwall Score: 0.01
    • Extracellular Score: 0.02
    • Internal Helices: 0
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.002693
    • TAT(Tat/SPI): 0.001434
    • LIPO(Sec/SPII): 0.000451
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_000185363 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MTNSVFQGRSFLAEKDFTRAELEYLIGLSAHLKDLKKRNIQHHYLAGKNIALLFEKTSTRTRAAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRMFDGIEFRGFSQRMVEELAEFSGVPVWNGLTDEWHPTQMLADYLTVQENFGRLEGLTLVYCGDGRNNVANSLLVTGAILGVNVHIFSPKELFPEKEIVELAEGFAKESGAHVLITEDADEAVKDADVLYTDVWVSMGEEDKFAERVALLKPYQVNMDLVKKAGNENLIFLHCLPAFHDTHTVYGKDVAEKFGVEEMEVTDEVFRSKYARHFDQAENRMHTIKAVMAATLGNLYIPKV

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

Retrieved from "http://pneumowiki.med.uni-greifswald.de/index.php?title=EL263_RS10770&oldid=50977"