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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 12-FEB-2025

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae HU-OH
  • locus tag: EL271_RS01345 [old locus tag: SPOH_0241 ]
  • pan locus tag?: PNEUPAN001003000
  • symbol: EL271_RS01345
  • pan gene symbol?: luxA
  • synonym:
  • product: LLM class flavin-dependent oxidoreductase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: EL271_RS01345 [old locus tag: SPOH_0241 ]
  • symbol: EL271_RS01345
  • product: LLM class flavin-dependent oxidoreductase
  • replicon: chromosome
  • strand: +
  • coordinates: 232425..233474
  • length: 1050
  • essential: unknown

⊟Accession numbers[edit | edit source]

  • Location: NZ_AP018937 (232425..233474) NCBI
  • BioCyc: EL271_RS01345 BioCyc
  • MicrobesOnline:
  • PneumoBrowse for strain D39V: SPV_0249 PneumoBrowse

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    ATGGTAGAATTGGGAATTTCAACATTTGGGGAAATAACGGAGCTTGAAGGGACTGGACAA
    ACTTACAGTCATGCTGAACGCATTCGCCAGTTGGTGGCAGAGATTGAGCTGGCTGACAAG
    GTTGGTTTGGACGTATATGGGATTGGCGAGCACCATCGGGCGGATTTTGCAGTATCAGCC
    CCAGAGATTGTCCTGGCCGCTGGGGCAGTCAATACCAAGAAAATCCGTTTGACCAGTGCA
    GTCAGCATTCTGTCAAGCATGGACCCGATTCGTTTGTTCCAACAGTATGCCACTATCGAT
    GCTTTGTCAAATGGACGATCGGAGATTATGGCTGGAAGGGGCTCTTTCACGGAATCTTTC
    CCTCTGTTTGGTTATGACTTGAAAGACTACGACTCTCTTTTTGATGAGAAATTAGACTTG
    CTTCAGTTAGTCAATGAAAAGACCAAGTTAGACTGGCAAGGTCGATTGACTCAAACGATT
    GCTGGTAAAGAAGTTTATCCTCGTCCAGTTCAGGACAAATTGCCCTTGTGGATAGCTACA
    GGTGGTCATGTCGAATCAACAGTGAAGATTGCTCAGGCTGGTCTACCGATTGTATATGCT
    ATTATTGGTGGTAATCCACGTTATTTTAAAAAGTTGATTCAGGCTTATCGTGAGATTGGA
    AGCGAAGCGGGCCATGCTGACAAAGACTTGAAAGTGGGAGCCCATTCTTGGGGGTGGATT
    GCGGAAGATGGTGAGCAGGCGGTGAAAGATTATTTCCATCCGACTAAGCAAGTGGTGGAT
    GCTATTTCCAAAGACCGTCCGCACTGGCAGGAATTGCGTTATGAGCAATATTTGGAGCAG
    GTAGGGTCAAATGGCGCCATGTTTGTTGGCAATCCAGATCAGGTGGCCGAAAAATTGATT
    CGCATGATAGAGGATTTAGGATTGGACCGCTTCATGCTTCATCTACCGCTTGGTTCTATG
    CCTCATGACCAGGTTCTGAGAGCTATTGAACTCTTCGGAACACAAGTTGCACCCAAAGTA
    CGAGCTTATTTTGCTATGAAAGAGGCTTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1050

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: EL271_RS01345 [old locus tag: SPOH_0241 ]
  • symbol: EL271_RS01345
  • description: LLM class flavin-dependent oxidoreductase
  • length: 349
  • theoretical pI: 5.43379
  • theoretical MW: 38875
  • GRAVY: -0.206304

⊟Function[edit | edit source]

  • reaction:
    EC 1.-.-.-?  ExPASy
  • TIGRFAM:
    probable oxidoreductase, LLM family (TIGR03858; EC 1.-.-.-; HMM-score: 523.3)
    and 19 more
    Unknown function Enzymes of unknown specificity putative luciferase-like monooxygenase, FMN-dependent, CE1758 family (TIGR04036; EC 1.-.-.-; HMM-score: 166.9)
    Unknown function Enzymes of unknown specificity probable F420-dependent oxidoreductase, Rv2161c family (TIGR03619; EC 1.-.-.-; HMM-score: 85.2)
    natural product biosynthesis luciferase-like monooxygenase domain (TIGR04020; EC 1.-.-.-; HMM-score: 84.3)
    Unknown function Enzymes of unknown specificity putative FMN-dependent luciferase-like monooxygenase, KPN_01858 family (TIGR04027; EC 1.-.-.-; HMM-score: 75.7)
    Unknown function Enzymes of unknown specificity luciferase family oxidoreductase, group 1 (TIGR03558; EC 1.-.-.-; HMM-score: 69.6)
    Metabolism Central intermediary metabolism Sulfur metabolism dimethyl sulfone monooxygenase SfnG (TIGR04021; EC 1.14.-.-; HMM-score: 51.8)
    Unknown function Enzymes of unknown specificity luciferase-type oxidoreductase, BA3436 family (TIGR03571; EC 1.-.-.-; HMM-score: 51.2)
    Metabolism Energy metabolism Methanogenesis 5,10-methylenetetrahydromethanopterin reductase (TIGR03555; EC 1.5.98.2; HMM-score: 47.6)
    Unknown function Enzymes of unknown specificity probable F420-dependent oxidoreductase, Rv1855c family (TIGR03560; HMM-score: 46.9)
    Unknown function Enzymes of unknown specificity probable F420-dependent oxidoreductase, MSMEG_2516 family (TIGR03621; HMM-score: 40.2)
    Unknown function Enzymes of unknown specificity probable F420-dependent oxidoreductase, Rv3520c family (TIGR03559; HMM-score: 37.6)
    Unknown function Enzymes of unknown specificity FMN-dependent oxidoreductase, nitrilotriacetate monooxygenase family (TIGR03860; EC 1.-.-.-; HMM-score: 34.9)
    Metabolism Central intermediary metabolism Sulfur metabolism alkanesulfonate monooxygenase, FMNH(2)-dependent (TIGR03565; EC 1.14.14.5; HMM-score: 32.1)
    Unknown function Enzymes of unknown specificity probable F420-dependent oxidoreductase, MSMEG_3544 family (TIGR03854; HMM-score: 22.4)
    Unknown function Enzymes of unknown specificity F420-dependent oxidoreductase, MSMEG_4879 family (TIGR03564; EC 1.-.-.-; HMM-score: 18.9)
    Unknown function Enzymes of unknown specificity probable F420-dependent oxidoreductase, MSMEG_2906 family (TIGR03856; HMM-score: 18.8)
    Unknown function Enzymes of unknown specificity F420-dependent oxidoreductase, G6PDH family (TIGR03557; EC 1.-.-.-; HMM-score: 17.3)
    Unknown function Enzymes of unknown specificity coenzyme F420-dependent oxidoreductase, NP1902A family (TIGR04024; EC 1.14.-.-; HMM-score: 14.4)
    Unknown function Enzymes of unknown specificity probable F420-dependent oxidoreductase, MSMEG_2249 family (TIGR03857; HMM-score: 14.1)
  • TheSEED: data available for D39, Hungary19A-6, TIGR4
  • PFAM:
    no clan defined Bac_luciferase; Luciferase-like monooxygenase (PF00296; HMM-score: 147.1)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.9202
    • Cytoplasmic Membrane Score: 0.0362
    • Cell wall & surface Score: 0.0004
    • Extracellular Score: 0.0432
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.0074
    • TAT(Tat/SPI): 0.000402
    • LIPO(Sec/SPII): 0.000558
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_000229773 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MVELGISTFGEITELEGTGQTYSHAERIRQLVAEIELADKVGLDVYGIGEHHRADFAVSAPEIVLAAGAVNTKKIRLTSAVSILSSMDPIRLFQQYATIDALSNGRSEIMAGRGSFTESFPLFGYDLKDYDSLFDEKLDLLQLVNEKTKLDWQGRLTQTIAGKEVYPRPVQDKLPLWIATGGHVESTVKIAQAGLPIVYAIIGGNPRYFKKLIQAYREIGSEAGHADKDLKVGAHSWGWIAEDGEQAVKDYFHPTKQVVDAISKDRPHWQELRYEQYLEQVGSNGAMFVGNPDQVAEKLIRMIEDLGLDRFMLHLPLGSMPHDQVLRAIELFGTQVAPKVRAYFAMKEA

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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