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serotype 1

NCBI: 16-DEC-2024

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae CGSP14
  • locus tag: SPCG_RS01450 [old locus tag: SPCG_0277 ]
  • pan locus tag?: PNEUPAN001003000
  • symbol: SPCG_RS01450
  • pan gene symbol?: luxA
  • synonym:
  • product: LLM class flavin-dependent oxidoreductase

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: SPCG_RS01450 [old locus tag: SPCG_0277 ]
  • symbol: SPCG_RS01450
  • product: LLM class flavin-dependent oxidoreductase
  • replicon: chromosome
  • strand: +
  • coordinates: 263826..264875
  • length: 1050
  • essential: unknown

⊟Accession numbers[edit | edit source]

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    ATGGTAGAATTGGGAATTTCAACATTTGGGGAAATAACGGAGCTTGAAGGGACTGGACAA
    ACTTACAGTCATGCTGAACGCATTCGCCAGTTGGTGGCAGAGATTGAGCTGGCTGACAAG
    ATTGGTTTGGACGTATATGGGATTGGCGAGCACCATCGGGCGGATTTTGCAGTATCAGCC
    CCAGAGATTGTCCTGGCCGCTGGGGCAGTCAATACCAAGAAAATCCGTTTGACCAGTGCA
    GTCAGCATTCTGTCAAGCATGGATCCGATTCGTTTGTTCCAACAGTATGCCACTATCGAT
    GCTTTGTCAAATGGACGATCGGAGATTATGGCTGGAAGGGGCTCTTTCACGGAATCTTTC
    CCTCTGTTTGGTTATGACTTGAAAGACTACGACTCTCTTTTTGATGAGAAATTAGACTTG
    CTTCAGTTAGTCAATGAAAAGACCAAGTTAGACTGGCAAGGTCGATTGACTCAAACGATT
    GCTGGTAAAGAAGTTTATCCTCGTCCAGTTCAGGACAAATTGCCCTTGTGGATAGCTACA
    GGTGGTCATGTCGAATCAACAGTGAAGATTGCTCAGGCTGGTCTACCGATTGTATATGCT
    ATTATTGGTGGTAATCCACGTTATTTTAAAAAGTTGATTCAGGCTTATCGTGAGATTGGA
    AGCGAAGCGGGCCATGCTGACAAAGACTTGAAAGTGGGAGCCCATTCTTGGGGGTGGATT
    GCGGAAGATGGTGAGCAGGCGGTGAAAGATTATTTCCATCCGACTAAGCAAGTGGTGGAT
    GCTATTTCCAAAGACCGTCCGCACTGGCAGGAATTGCGTTATGAGCAATATTTGGAGCAG
    GTAGGGCCAAATGGCGCCATGTTTGTTGGCAATCCAGATCAGGTGGCCGAAAAATTGATT
    CGCATGATAGAGGATTTAGGATTGGACCGCTTCATGCTTCATCTACCGCTTGGTTCTATG
    CCTCATGACCAGGTTCTGAGAGCTATTGAACTCTTCGGAACACAAGTTGCACCCAAAGTA
    CGAGCTTATTTTGCTATGAAAGAGGCTTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    600
    660
    720
    780
    840
    900
    960
    1020
    1050

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: SPCG_RS01450 [old locus tag: SPCG_0277 ]
  • symbol: SPCG_RS01450
  • description: LLM class flavin-dependent oxidoreductase
  • length: 349
  • theoretical pI: 5.43379
  • theoretical MW: 38899.1
  • GRAVY: -0.207736

⊟Function[edit | edit source]

  • reaction:
    EC 1.-.-.-?  ExPASy
  • TIGRFAM:
    probable oxidoreductase, LLM family (TIGR03858; EC 1.-.-.-; HMM-score: 522.4)
    and 18 more
    Unknown function Enzymes of unknown specificity putative luciferase-like monooxygenase, FMN-dependent, CE1758 family (TIGR04036; EC 1.-.-.-; HMM-score: 165.5)
    Unknown function Enzymes of unknown specificity probable F420-dependent oxidoreductase, Rv2161c family (TIGR03619; EC 1.-.-.-; HMM-score: 84.9)
    natural product biosynthesis luciferase-like monooxygenase domain (TIGR04020; EC 1.-.-.-; HMM-score: 83.9)
    Unknown function Enzymes of unknown specificity putative FMN-dependent luciferase-like monooxygenase, KPN_01858 family (TIGR04027; EC 1.-.-.-; HMM-score: 74.6)
    Unknown function Enzymes of unknown specificity luciferase family oxidoreductase, group 1 (TIGR03558; EC 1.-.-.-; HMM-score: 68.9)
    Unknown function Enzymes of unknown specificity luciferase-type oxidoreductase, BA3436 family (TIGR03571; EC 1.-.-.-; HMM-score: 51.4)
    Metabolism Central intermediary metabolism Sulfur metabolism dimethyl sulfone monooxygenase SfnG (TIGR04021; EC 1.14.-.-; HMM-score: 50.9)
    Metabolism Energy metabolism Methanogenesis 5,10-methylenetetrahydromethanopterin reductase (TIGR03555; EC 1.5.98.2; HMM-score: 46.6)
    Unknown function Enzymes of unknown specificity probable F420-dependent oxidoreductase, Rv1855c family (TIGR03560; HMM-score: 46.6)
    Unknown function Enzymes of unknown specificity probable F420-dependent oxidoreductase, MSMEG_2516 family (TIGR03621; HMM-score: 38.7)
    Unknown function Enzymes of unknown specificity probable F420-dependent oxidoreductase, Rv3520c family (TIGR03559; HMM-score: 37.3)
    Unknown function Enzymes of unknown specificity FMN-dependent oxidoreductase, nitrilotriacetate monooxygenase family (TIGR03860; EC 1.-.-.-; HMM-score: 33.7)
    Metabolism Central intermediary metabolism Sulfur metabolism alkanesulfonate monooxygenase, FMNH(2)-dependent (TIGR03565; EC 1.14.14.5; HMM-score: 31.6)
    Unknown function Enzymes of unknown specificity probable F420-dependent oxidoreductase, MSMEG_3544 family (TIGR03854; HMM-score: 22.5)
    Unknown function Enzymes of unknown specificity probable F420-dependent oxidoreductase, MSMEG_2906 family (TIGR03856; HMM-score: 19.1)
    Unknown function Enzymes of unknown specificity F420-dependent oxidoreductase, MSMEG_4879 family (TIGR03564; EC 1.-.-.-; HMM-score: 19)
    Unknown function Enzymes of unknown specificity coenzyme F420-dependent oxidoreductase, NP1902A family (TIGR04024; EC 1.14.-.-; HMM-score: 14.3)
    Unknown function Enzymes of unknown specificity probable F420-dependent oxidoreductase, MSMEG_2249 family (TIGR03857; HMM-score: 14.2)
  • TheSEED: see SPCG_0277
  • PFAM:
    no clan defined Bac_luciferase; Luciferase-like monooxygenase (PF00296; HMM-score: 146.3)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 7.5
    • Cytoplasmic Membrane Score: 1.15
    • Cellwall Score: 0.62
    • Extracellular Score: 0.73
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.9314
    • Cytoplasmic Membrane Score: 0.03
    • Cell wall & surface Score: 0.0003
    • Extracellular Score: 0.0382
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.007182
    • TAT(Tat/SPI): 0.00037
    • LIPO(Sec/SPII): 0.000534
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_000229754 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MVELGISTFGEITELEGTGQTYSHAERIRQLVAEIELADKIGLDVYGIGEHHRADFAVSAPEIVLAAGAVNTKKIRLTSAVSILSSMDPIRLFQQYATIDALSNGRSEIMAGRGSFTESFPLFGYDLKDYDSLFDEKLDLLQLVNEKTKLDWQGRLTQTIAGKEVYPRPVQDKLPLWIATGGHVESTVKIAQAGLPIVYAIIGGNPRYFKKLIQAYREIGSEAGHADKDLKVGAHSWGWIAEDGEQAVKDYFHPTKQVVDAISKDRPHWQELRYEQYLEQVGPNGAMFVGNPDQVAEKLIRMIEDLGLDRFMLHLPLGSMPHDQVLRAIELFGTQVAPKVRAYFAMKEA

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You are kindly invited to share additional interesting facts.

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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