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PangenomeTIGR4
serotype 4
D39
serotype 2
D39V
serotype 2
Hungary19A-6
serotype 19A
EF3030
serotype 19F
670-6B
serotype 6B
6A-10
serotype 6A
70585
serotype 5
A026
serotype 19F
A66
serotype 3
AP200
serotype 11A
ASP0581
serotype 12F
ATCC 49619
serotype 19F
ATCC 700669
serotype 23F
BM6001
serotype 19F
BVJ1JL
serotype 1
CGSP14
serotype 14
G54
serotype 19F
HU-OH
serotype 3
Hu15
serotype 19A
Hu17
serotype 19A
INV104
serotype 1
INV200
serotype 14
JJA
serotype 14
MDRSPN001
serotype 19F
NCTC7465
serotype 1
NCTC7466
serotype 2
NU83127
serotype 4
OXC141
serotype 3
P1031
serotype 1
R6
serotype 2
SP49
serotype 19A
SPN032672
serotype 1
SPN034156
serotype 3
SPN034183
serotype 3
SPN994038
serotype 3
SPN994039
serotype 3
SPNA45
serotype 3
ST556
serotype 19F
TCH8431/19A
serotype 19A
Taiwan19F-14
serotype 19F
Xen35
serotype 4
gamPNI0373
serotype 1

NCBI: 12-FEB-2025

⊟Summary[edit | edit source]

  • organism: Streptococcus pneumoniae HU-OH
  • locus tag: EL271_RS04400 [old locus tag: SPOH_0812 ]
  • pan locus tag?: PNEUPAN001933000
  • symbol: frr
  • pan gene symbol?: frr
  • synonym:
  • product: ribosome recycling factor

⊟Genome View[edit | edit source]

⊟Gene[edit | edit source]

⊟General[edit | edit source]

  • type: CDS
  • locus tag: EL271_RS04400 [old locus tag: SPOH_0812 ]
  • symbol: frr
  • product: ribosome recycling factor
  • replicon: chromosome
  • strand: +
  • coordinates: 820679..821236
  • length: 558
  • essential: unknown other strains

⊟Accession numbers[edit | edit source]

  • Location: NZ_AP018937 (820679..821236) NCBI
  • BioCyc: EL271_RS04400 BioCyc
  • MicrobesOnline:
  • PneumoBrowse for strain D39V: SPV_0835 PneumoBrowse

⊟Phenotype[edit | edit source]

Share your knowledge and add information here. [edit]

⊟DNA sequence[edit | edit source]

  • 1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    ATGGCTAACATAATTATTGAAAAAGCTAAAGAGAGAATGACCCAGTCTCACCAATCACTT
    GCTCGTGAATTTGGTGGTATCCGTGCTGGTCGTGCCAATGCAAGCTTGCTTGACCGTGTA
    CATGTAGAATACTATGGAGTCGAAACTCCTCTTAACCAAATCGCTTCAATTACGATTCCA
    GAAGCGCGTGTTTTGTTGGTAACACCATTTGACAAGTCTTCATTGAAAGACATCGAACGT
    GCCTTGAACGCTTCTGATCTTGGTATCACACCGGCTAATGACGGTTCTGTGATTCGCTTG
    GTTATCCCAGCTCTTACAGAAGAAACTCGTCGTGACCTTGCTAAAGAAGTGAAGAAGGTC
    GGCGAAAATGCTAAAGTGGCTGTCCGCAATATCCGTCGCGATGCTATGGACGAAGCTAAG
    AAACAAGAAAAAGCAAAAGAAATCACTGAAGACGAATTGAAGACTCTTGAAAAAGATATT
    CAAAAAGTAACAGACGATGCTGTTAAACACATCGACGACATGACTGCTAACAAAGAGAAA
    GAACTTTTGGAAGTCTAA
    60
    120
    180
    240
    300
    360
    420
    480
    540
    558

⊟Protein[edit | edit source]

⊟General[edit | edit source]

  • locus tag: EL271_RS04400 [old locus tag: SPOH_0812 ]
  • symbol: Frr
  • description: ribosome recycling factor
  • length: 185
  • theoretical pI: 5.83161
  • theoretical MW: 20670.5
  • GRAVY: -0.508108

⊟Function[edit | edit source]

  • TIGRFAM:
    Genetic information processing Protein synthesis Translation factors ribosome recycling factor (TIGR00496; HMM-score: 233.7)
    and 1 more
    Metabolism Energy metabolism Pyruvate dehydrogenase pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit (TIGR03182; EC 1.2.4.1; HMM-score: 8.9)
  • TheSEED: data available for D39, Hungary19A-6, TIGR4
  • PFAM:
    no clan defined RRF; Ribosome recycling factor (PF01765; HMM-score: 210.8)
    and 8 more
    TPR (CL0020) 14-3-3; 14-3-3 protein (PF00244; HMM-score: 20.2)
    no clan defined DUF6076; Family of unknown function (DUF6076) (PF19553; HMM-score: 15.4)
    EspB; Enterobacterial EspB protein (PF05802; HMM-score: 15.2)
    YtxH; YtxH-like protein (PF12732; HMM-score: 13)
    DUF2390; Protein of unknown function (DUF2390) (PF09523; HMM-score: 11.7)
    Enkurin; Calmodulin-binding (PF13864; HMM-score: 11.5)
    CSN5_C; Cop9 signalosome subunit 5 C-terminal domain (PF18323; HMM-score: 8.4)
    TMPIT; TMPIT-like protein (PF07851; HMM-score: 6.2)

⊟Structure, modifications & cofactors[edit | edit source]

  • domains:
  • modifications:
  • cofactors:
  • effectors:

⊟Localization[edit | edit source]

  • PSORTb: Cytoplasmic
    • Cytoplasmic Score: 9.97
    • Cytoplasmic Membrane Score: 0
    • Cellwall Score: 0.01
    • Extracellular Score: 0.02
    • Internal Helices: 0
  • DeepLocPro: Cytoplasmic
    • Cytoplasmic Score: 0.997
    • Cytoplasmic Membrane Score: 0.0002
    • Cell wall & surface Score: 0
    • Extracellular Score: 0.0027
  • SignalP: no predicted signal peptide
    • SP(Sec/SPI): 0.004594
    • TAT(Tat/SPI): 0.00404
    • LIPO(Sec/SPII): 0.000647
  • predicted transmembrane helices (TMHMM): 0

⊟Accession numbers[edit | edit source]

  • GI:
  • RefSeq: WP_001273879 NCBI
  • UniProt:

⊟Protein sequence[edit | edit source]

  • MANIIIEKAKERMTQSHQSLAREFGGIRAGRANASLLDRVHVEYYGVETPLNQIASITIPEARVLLVTPFDKSSLKDIERALNASDLGITPANDGSVIRLVIPALTEETRRDLAKEVKKVGENAKVAVRNIRRDAMDEAKKQEKAKEITEDELKTLEKDIQKVTDDAVKHIDDMTANKEKELLEV

⊟Experimental data[edit | edit source]

  • protein localization:
  • interaction partners:

⊟Expression & Regulation[edit | edit source]

⊟Operon[edit | edit source]

⊟Regulation[edit | edit source]

  • regulator:

⊟Transcription[edit | edit source]

  • transcription start site:

⊟Expression data[edit | edit source]

⊟Biological Material[edit | edit source]

⊟Mutants[edit | edit source]

⊟Expression vector[edit | edit source]

⊟lacZ fusion[edit | edit source]

⊟GFP fusion[edit | edit source]

⊟two-hybrid system[edit | edit source]

⊟FLAG-tag construct[edit | edit source]

⊟Antibody[edit | edit source]

⊟Other Information[edit | edit source]

You can add further information about the gene and protein here. [edit]

⊟Literature[edit | edit source]

⊟References[edit | edit source]

⊟Relevant publications[edit | edit source]

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